ID A0A094PCI9_9ACTN Unreviewed; 478 AA.
AC A0A094PCI9;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=Permease {ECO:0000313|EMBL:KGA09250.1};
GN ORFNames=GM45_2270 {ECO:0000313|EMBL:KGA09250.1};
OS actinobacterium acAMD-5.
OC Bacteria; Actinomycetota; Actinomycetes.
OX NCBI_TaxID=1504319 {ECO:0000313|EMBL:KGA09250.1, ECO:0000313|Proteomes:UP000029322};
RN [1] {ECO:0000313|EMBL:KGA09250.1, ECO:0000313|Proteomes:UP000029322}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Ghai R., Mizuno C.M., Picazo A., Camacho A., Rodriguez-Valera F.;
RT "Key roles for freshwater Actinobacteria revealed by deep metagenomic
RT sequencing.";
RL Submitted (MAY-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC
CC 2.A.40) family. Azg-like subfamily. {ECO:0000256|ARBA:ARBA00005697}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KGA09250.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; JNSF01000005; KGA09250.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A094PCI9; -.
DR STRING; 1504319.GM45_2270; -.
DR PATRIC; fig|1504319.4.peg.457; -.
DR eggNOG; COG2252; Bacteria.
DR Proteomes; UP000029322; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015205; F:nucleobase transmembrane transporter activity; IEA:InterPro.
DR GO; GO:1904823; P:purine nucleobase transmembrane transport; IEA:UniProt.
DR InterPro; IPR045018; Azg-like.
DR InterPro; IPR006043; NCS2.
DR PANTHER; PTHR43337; XANTHINE/URACIL PERMEASE C887.17-RELATED; 1.
DR PANTHER; PTHR43337:SF1; XANTHINE_URACIL PERMEASE C887.17-RELATED; 1.
DR Pfam; PF00860; Xan_ur_permease; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 21..39
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 59..76
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 83..101
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 107..129
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 141..164
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 184..202
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 207..223
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 269..290
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 357..374
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 380..399
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 411..442
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 454..472
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 478 AA; 49425 MW; 95B0BB7B46406DB6 CRC64;
MLDKMFKIKE RGSSVATEVR GGLVTFLTMA YIIVLNPLIL GFTPDINGKF LAGGDAPNLA
MIAAATALVA GILTILMGTA TNFPLALATG LGINSFVARI AADYMTWAEV MGLVVLEGLI
ITVLVLTGFR VAVFKAVPAQ LKIAISVGIG LFIALIGLVD AGFVRRTAAG PVPVELGSGG
TLDGWPVLVF VTGVLVMTIL YARKVKGAIL IGVLGATAIA VALEESLKIG PSFISADEFN
PKGWGLNVPS IPDSFVATPD FGLLGQFDLL GGFATAGIIT AALFVFTLLI TDFFDTMGTM
TAISAEAGLS DKDGNVPNAD RILLVDSLAA MAGGAGGISS NTSYIESASG VGEGAKTGLA
SVVTGIAFLF ATFLSPLVNL VPYEAATPAL IVVGFLMMTQ IKGIDWSDIT IALPAFLIII
LMPFTYSIAT GIGAGFVTYV ALKAFTGKAS KVHPMMWISA TAFLIYFATA PIKELFGV
//
