ID A0A094PQ65_9ACTN Unreviewed; 429 AA.
AC A0A094PQ65;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE SubName: Full=Membrane protein {ECO:0000313|EMBL:KGA04131.1};
GN ORFNames=GM47_2115 {ECO:0000313|EMBL:KGA04131.1};
OS actinobacterium acIB-AMD-6.
OC Bacteria; Actinomycetota; Actinomycetes.
OX NCBI_TaxID=1504321 {ECO:0000313|EMBL:KGA04131.1, ECO:0000313|Proteomes:UP000029266};
RN [1] {ECO:0000313|EMBL:KGA04131.1, ECO:0000313|Proteomes:UP000029266}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Ghai R., Mizuno C.M., Picazo A., Camacho A., Rodriguez-Valera F.;
RT "Key roles for freshwater Actinobacteria revealed by deep metagenomic
RT sequencing.";
RL Submitted (MAY-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KGA04131.1}.
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DR EMBL; JNSH01000021; KGA04131.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A094PQ65; -.
DR PATRIC; fig|1504321.4.peg.432; -.
DR Proteomes; UP000029266; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR CDD; cd04590; CBS_pair_CorC_HlyC_assoc; 1.
DR Gene3D; 3.30.465.10; -; 1.
DR Gene3D; 3.10.580.10; CBS-domain; 1.
DR InterPro; IPR000644; CBS_dom.
DR InterPro; IPR046342; CBS_dom_sf.
DR InterPro; IPR002550; CNNM.
DR InterPro; IPR036318; FAD-bd_PCMH-like_sf.
DR InterPro; IPR016169; FAD-bd_PCMH_sub2.
DR InterPro; IPR044751; Ion_transp-like_CBS.
DR InterPro; IPR005170; Transptr-assoc_dom.
DR PANTHER; PTHR43099; UPF0053 PROTEIN YRKA; 1.
DR PANTHER; PTHR43099:SF2; UPF0053 PROTEIN YRKA; 1.
DR Pfam; PF00571; CBS; 2.
DR Pfam; PF01595; CNNM; 1.
DR Pfam; PF03471; CorC_HlyC; 1.
DR SMART; SM01091; CorC_HlyC; 1.
DR SUPFAM; SSF54631; CBS-domain pair; 1.
DR SUPFAM; SSF56176; FAD-binding/transporter-associated domain-like; 1.
DR PROSITE; PS51371; CBS; 2.
DR PROSITE; PS51846; CNNM; 1.
PE 4: Predicted;
KW CBS domain {ECO:0000256|ARBA:ARBA00023122, ECO:0000256|PROSITE-
KW ProRule:PRU00703}; Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|PROSITE-
KW ProRule:PRU01193}; Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|PROSITE-
KW ProRule:PRU01193};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989, ECO:0000256|PROSITE-
KW ProRule:PRU01193}.
FT TRANSMEM 6..30
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 60..80
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 100..124
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 136..158
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 1..204
FT /note="CNNM transmembrane"
FT /evidence="ECO:0000259|PROSITE:PS51846"
FT DOMAIN 218..277
FT /note="CBS"
FT /evidence="ECO:0000259|PROSITE:PS51371"
FT DOMAIN 282..339
FT /note="CBS"
FT /evidence="ECO:0000259|PROSITE:PS51371"
SQ SEQUENCE 429 AA; 46715 MW; E320DD505FFE530E CRC64;
MADGALISIA IVLGLIALGG IFVAAEIALI SLRESQVKQL ASKGKRGVRV AKLTSNPNRF
LAAVQVGITL CGFLSAAFGA EQLGTYVIPA LERAGFSEQA SEILSIVGIT LVIVYISLVF
GELVPKRLAL FKTEKIALAT AAIIDRVAII FKPVIWLLSH STDLIVRIFG ITAQTQRSKI
SDVELMELVS GHTDLSTEER EIVEEVFNTS DRLIHEVMVP RTEVDFLDAS LSISEARKVA
AELAHSRYPV VRGSSDEIIG FLHVRDLLNP KLDDAQITIM EIIRNVIFLP GTKGVLPALT
EMRSKRQHIA IVLDEYGGTD GIITLENLVE CLIGEIHDEY DGHEGEPKPE QRTGDIEIDG
LISLEDLQDL AGITLPEGPY ETVSGFIMNY LGRIAQVGDV VRINGARFTI TSMTGKRAGQ
ILLSKEVRK
//
