ID   A0A094PQI7_9ACTN        Unreviewed;       570 AA.
AC   A0A094PQI7;
DT   26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT   26-NOV-2014, sequence version 1.
DT   27-MAR-2024, entry version 23.
DE   SubName: Full=Putative fatty-acid--CoA ligase {ECO:0000313|EMBL:KGA04271.1};
GN   ORFNames=GM46_13060 {ECO:0000313|EMBL:KGA04271.1};
OS   actinobacterium acAcidi.
OC   Bacteria; Actinomycetota; Actinomycetes.
OX   NCBI_TaxID=1504320 {ECO:0000313|EMBL:KGA04271.1, ECO:0000313|Proteomes:UP000029305};
RN   [1] {ECO:0000313|EMBL:KGA04271.1, ECO:0000313|Proteomes:UP000029305}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Ghai R., Mizuno C.M., Picazo A., Camacho A., Rodriguez-Valera F.;
RT   "Key roles for freshwater Actinobacteria revealed by deep metagenomic
RT   sequencing.";
RL   Submitted (MAY-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KGA04271.1}.
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DR   EMBL; JNSG01000124; KGA04271.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A094PQI7; -.
DR   PATRIC; fig|1504320.4.peg.2625; -.
DR   Proteomes; UP000029305; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.300.30; -; 1.
DR   Gene3D; 3.40.50.980; -; 2.
DR   InterPro; IPR025110; AMP-bd_C.
DR   InterPro; IPR045851; AMP-bd_C_sf.
DR   InterPro; IPR020845; AMP-binding_CS.
DR   InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR   PANTHER; PTHR43767; LONG-CHAIN-FATTY-ACID--COA LIGASE; 1.
DR   PANTHER; PTHR43767:SF1; NONRIBOSOMAL PEPTIDE SYNTHASE PES1 (EUROFUNG)-RELATED; 1.
DR   Pfam; PF00501; AMP-binding; 1.
DR   Pfam; PF13193; AMP-binding_C; 1.
DR   SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR   PROSITE; PS00455; AMP_BINDING; 1.
PE   4: Predicted;
KW   Ligase {ECO:0000313|EMBL:KGA04271.1}; Membrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        103..122
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          50..431
FT                   /note="AMP-dependent synthetase/ligase"
FT                   /evidence="ECO:0000259|Pfam:PF00501"
FT   DOMAIN          481..557
FT                   /note="AMP-binding enzyme C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF13193"
SQ   SEQUENCE   570 AA;  61821 MW;  878AF2D6963D545B CRC64;
     MINHYRAARA ELDAPGSPFA TTMSEVRGVT MKTFVSAPPT MRVIWENSIG HADKDYIVYE
     DERYTYGDIH AQVRKLAQYL VEHGVTPGTR VALAMRNYPE WVVGYWAILS VGAAVVGMNA
     WWTTPEMEYA LNDSAPVVLI ADDERLERFE QIEKAPAVHI LGVRTDRALP AGSGRWADVL
     AMADPGVLPT VEIDTDDDVT IFYTSGTTGF PKGAQLTHRG SVSNIFNMLT MTMAANSAEA
     KGIAAGDIPA PTTAPSAFPP AFMAPTPLFH VTACNCILHP ATVMGAKLVL TYKWEPGRAL
     ELIERERVTT LSGVPTMSRE LLLHPDWETR DTSSLQGMGG GGAPLQPDLV HKIAGALKGG
     QPSTGYGMTE TCGIITANSA RWLIAKPASC GPLVPTLEAK FVDEDGNDLP SGPDTVGVLC
     VKGAVIIKGY LNRPEANAET IQDGWLNTGD IARIDEDGFV FIVDRAKDMV LRGGENVYCS
     EVETAIYHHE SIAEAAVFGI PDERLGEEVA VVLVLRPGKT LGEDELRTFL GATLAKHKIP
     SKVWFRDEPI PRNASGKFLK RELRKELIGE
//