ID A0A094RYA7_9ACTN Unreviewed; 436 AA.
AC A0A094RYA7;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 24-JAN-2024, entry version 26.
DE RecName: Full=F420-0--gamma-glutamyl ligase {ECO:0008006|Google:ProtNLM};
GN ORFNames=GM44_4355 {ECO:0000313|EMBL:KGA10253.1};
OS actinobacterium acAMD-2.
OC Bacteria; Actinomycetota; Actinomycetes.
OX NCBI_TaxID=1504318 {ECO:0000313|EMBL:KGA10253.1, ECO:0000313|Proteomes:UP000029252};
RN [1] {ECO:0000313|EMBL:KGA10253.1, ECO:0000313|Proteomes:UP000029252}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Ghai R., Mizuno C.M., Picazo A., Camacho A., Rodriguez-Valera F.;
RT "Key roles for freshwater Actinobacteria revealed by deep metagenomic
RT sequencing.";
RL Submitted (MAY-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KGA10253.1}.
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DR EMBL; JNSE01000034; KGA10253.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A094RYA7; -.
DR STRING; 1504318.GM44_4355; -.
DR PATRIC; fig|1504318.4.peg.877; -.
DR Proteomes; UP000029252; Unassembled WGS sequence.
DR GO; GO:0043773; F:coenzyme F420-0 gamma-glutamyl ligase activity; IEA:InterPro.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR GO; GO:0008152; P:metabolic process; IEA:UniProtKB-KW.
DR CDD; cd20607; FbiB_C-like; 1.
DR Gene3D; 3.30.1330.100; CofE-like; 2.
DR Gene3D; 3.40.109.10; NADH Oxidase; 1.
DR InterPro; IPR008225; F420-0_g-glutamyl_ligase.
DR InterPro; IPR002847; F420-0_gamma-glut_ligase-dom.
DR InterPro; IPR019943; F420_FbiB_C.
DR InterPro; IPR029479; Nitroreductase.
DR InterPro; IPR000415; Nitroreductase-like.
DR NCBIfam; TIGR01916; F420_cofE; 1.
DR NCBIfam; TIGR03553; F420_FbiB_CTERM; 1.
DR PANTHER; PTHR47917; -; 1.
DR PANTHER; PTHR47917:SF1; COENZYME F420:L-GLUTAMATE LIGASE; 1.
DR Pfam; PF01996; F420_ligase; 1.
DR Pfam; PF00881; Nitroreductase; 1.
DR SUPFAM; SSF144010; CofE-like; 1.
DR SUPFAM; SSF55469; FMN-dependent nitroreductase-like; 1.
PE 4: Predicted;
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Ligase {ECO:0000256|ARBA:ARBA00022598};
KW Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW Manganese {ECO:0000256|ARBA:ARBA00023211};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Multifunctional enzyme {ECO:0000256|ARBA:ARBA00023268};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Potassium {ECO:0000256|ARBA:ARBA00022958}.
FT DOMAIN 13..205
FT /note="Coenzyme F420:L-glutamate ligase-like"
FT /evidence="ECO:0000259|Pfam:PF01996"
FT DOMAIN 248..416
FT /note="Nitroreductase"
FT /evidence="ECO:0000259|Pfam:PF00881"
SQ SEQUENCE 436 AA; 47013 MW; E0CFDF7208420DF4 CRC64;
MTNIEVFALE GIGEVAAGDD LISVIAQAYA NYQPQDGDVL VVTSKIVSKA EARTLPAEDR
AEAITAESFG EVATNGPTRI VRTRHGFVMA AAGVDASNTA ANTILLLPLD PDATARQLRA
GLQTRLGITL GVIISDTFGR PWREGLTDNA IGVAGVRVLH DHRGELDAQG RTLEQTVVAT
ADELASAADL VKGKNSNCPV AVIRGSQTVH GEDGPGARAL VRASHTDLFA LGTQQAKDLG
RKEAVQLRRT VRTWSDQLVA HELIGECVAA ALTAPAPHHT TPWRFVHVVE PATRKELLAR
MADRWEHDLA SDGLTPESVR KRVERGQLLE RCPELVIPVL VLEGQHDYPD ERRKTAERDM
FVLSMGAAVQ SFMVTAATLR LGTAWVSSTL FCPDDVRPVL DMPAQWHPMG AIAVGYPLGD
VTPRPSRDSS PFLIQK
//
