ID   A0A094ZGZ8_SCHHA        Unreviewed;      1150 AA.
AC   A0A094ZGZ8;
DT   26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT   26-NOV-2014, sequence version 1.
DT   27-MAR-2024, entry version 40.
DE   SubName: Full=C-Jun-amino-terminal kinase-interacting protein 3 {ECO:0000313|EMBL:KGB33735.1};
GN   ORFNames=MS3_01921 {ECO:0000313|EMBL:KGB33735.1};
OS   Schistosoma haematobium (Blood fluke).
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Trematoda;
OC   Digenea; Strigeidida; Schistosomatoidea; Schistosomatidae; Schistosoma.
OX   NCBI_TaxID=6185 {ECO:0000313|EMBL:KGB33735.1};
RN   [1] {ECO:0000313|EMBL:KGB33735.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=22246508; DOI=10.1038/ng.1065;
RA   Young N.D., Jex A.R., Li B., Liu S., Yang L., Xiong Z., Li Y.,
RA   Cantacessi C., Hall R.S., Xu X., Chen F., Wu X., Zerlotini A., Oliveira G.,
RA   Hofmann A., Zhang G., Fang X., Kang Y., Campbell B.E., Loukas A.,
RA   Ranganathan S., Rollinson D., Rinaldi G., Brindley P.J., Yang H., Wang J.,
RA   Wang J., Gasser R.B.;
RT   "Whole-genome sequence of Schistosoma haematobium.";
RL   Nat. Genet. 44:221-225(2012).
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DR   EMBL; KL250566; KGB33735.1; -; Genomic_DNA.
DR   RefSeq; XP_012793505.1; XM_012938051.1.
DR   AlphaFoldDB; A0A094ZGZ8; -.
DR   STRING; 6185.A0A094ZGZ8; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR   GO; GO:0005078; F:MAP-kinase scaffold activity; IEA:InterPro.
DR   GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR   Gene3D; 1.20.5.1000; arf6 gtpase in complex with a specific effector, jip4; 1.
DR   InterPro; IPR039911; JIP3/JIP4.
DR   InterPro; IPR032486; JIP_LZII.
DR   InterPro; IPR019143; JNK/Rab-associated_protein-1_N.
DR   InterPro; IPR034743; RH1.
DR   InterPro; IPR034744; RH2.
DR   PANTHER; PTHR13886:SF7; C-JUN-AMINO-TERMINAL KINASE-INTERACTING PROTEIN 4-LIKE ISOFORM X1; 1.
DR   PANTHER; PTHR13886; JNK/SAPK-ASSOCIATED PROTEIN; 1.
DR   Pfam; PF16471; JIP_LZII; 1.
DR   Pfam; PF09744; Jnk-SapK_ap_N; 1.
DR   Pfam; PF19056; WD40_2; 1.
DR   PROSITE; PS51776; RH1; 1.
DR   PROSITE; PS51777; RH2; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW   Kinase {ECO:0000313|EMBL:KGB33735.1};
KW   Transferase {ECO:0000313|EMBL:KGB33735.1}.
FT   DOMAIN          18..106
FT                   /note="RH1"
FT                   /evidence="ECO:0000259|PROSITE:PS51776"
FT   DOMAIN          316..389
FT                   /note="RH2"
FT                   /evidence="ECO:0000259|PROSITE:PS51777"
FT   REGION          1..32
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          159..197
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          100..138
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          214..290
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        181..195
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1150 AA;  129378 MW;  5AB5D0C1585FD480 CRC64;
     MDNYIQAGRR LQSSDDHEDA ISSTDDGSQP ISQSVQDLAN DIYKEFESLI KLYGNGFLHN
     LMPLVIRALE NLDSLHSENS DLHLKSLVLS DDHRLLSGEY EKEKKLRKAA ENRLFRLEDD
     LEEERRQHEE KTVSYDANVR ILENRVKSLN EQTKRLSEPC FDELSQGDLP EDEGHDIKSH
     DGSCTTPQPQ SSEPLGSEFA EPVELEVDGD LTDYAGVRRE IQNLIKENQE LIQTKNALKI
     VTNDLIGRID ELSCQNFQFS SELNALITNR ASMLLRIKDL EQENGQLRRE FENSDLYGSL
     PGDEISDSEH LPLSMRFRFS RVEMARVLLE RNQYKEQLLE LQEAVHSTHN LKVQQTSKLA
     NTIHGTKRGR IRAFFAKLFN SQQSSSKSFN LSTSMNTSQS TIQSMHNSIS RLSTPNEFTI
     SSSLSQINET NNPNTSMSIQ KTTSDSDLNQ HLTNWKISMK QTCIRDLNDS TESSQRRHQR
     CTSPIQWYSH RNEHTLDRRN LKVAYVYPLN DYPGSVELRC AAVTYPYHST SHSSASSPTM
     NNLLFTAYFR NQLESSKDDD YVNTTVLSTY SNSDQLEHPK SHEQQQSKVG IFKQSMYNHS
     IGNLSSDHDS LDFSAVIDDQ FSDVQSNIIW LSSFSLKHDL TAIKAPSSSS STSSSSSTAF
     TSSDYSGRIK SLITIVHVDY KSCQSVDSFA ICSSTVLCIC SVPEASVEDL TCLENTDHYW
     KMLPMDSFSG DLETGQSLTA DMLETKTKKY DVNAPCSLNE CTEFKFLDCD NTNNNTPQKI
     NKIVQESKYH RTSTPTSSSS SHFSSINALG IIGSVNDVDE VTMSYVATRR RFLIHHVDCD
     SCISNNGDCA VQPSKEMFSS HSSTTNDNLV TQYPCSSSTQ HSHYQYSSRK CYSRCSASPT
     SAQPTVWLGC QNGDLYVHSS VSDWRKCLHA IRLPDSVTQI CHLAGRVFVS LANGQIVVFR
     RHRFHRTNNG NSCLANINSS DCGNISKLKS SSLAITTLKS MNDRLWIGTS AGLIITIQFQ
     DSLFNRTFQQ TSCERQKDSA NLSKRICKAI LDCSSAQISA HQHTAPVRFF VTPTVIQQNE
     DNVNNQCAST CQTTGSMNKP KRRVEKPSFF MVTGGEGHLI DSHKDSASTN TLHQSDNRSS
     NCSHLIIWQL
//