ID A0A094ZIA4_SCHHA Unreviewed; 515 AA.
AC A0A094ZIA4;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 24-JAN-2024, entry version 42.
DE SubName: Full=ETS-related transcription factor Elf-1 {ECO:0000313|EMBL:KGB33677.1};
GN ORFNames=MS3_01856 {ECO:0000313|EMBL:KGB33677.1};
OS Schistosoma haematobium (Blood fluke).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Trematoda;
OC Digenea; Strigeidida; Schistosomatoidea; Schistosomatidae; Schistosoma.
OX NCBI_TaxID=6185 {ECO:0000313|EMBL:KGB33677.1};
RN [1] {ECO:0000313|EMBL:KGB33677.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=22246508; DOI=10.1038/ng.1065;
RA Young N.D., Jex A.R., Li B., Liu S., Yang L., Xiong Z., Li Y.,
RA Cantacessi C., Hall R.S., Xu X., Chen F., Wu X., Zerlotini A., Oliveira G.,
RA Hofmann A., Zhang G., Fang X., Kang Y., Campbell B.E., Loukas A.,
RA Ranganathan S., Rollinson D., Rinaldi G., Brindley P.J., Yang H., Wang J.,
RA Wang J., Gasser R.B.;
RT "Whole-genome sequence of Schistosoma haematobium.";
RL Nat. Genet. 44:221-225(2012).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|RuleBase:RU004019}.
CC -!- SIMILARITY: Belongs to the ETS family. {ECO:0000256|ARBA:ARBA00005562,
CC ECO:0000256|RuleBase:RU004019}.
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DR EMBL; KL250562; KGB33677.1; -; Genomic_DNA.
DR RefSeq; XP_012793442.1; XM_012937988.1.
DR AlphaFoldDB; A0A094ZIA4; -.
DR STRING; 6185.A0A094ZIA4; -.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IEA:InterPro.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR000418; Ets_dom.
DR InterPro; IPR046328; ETS_fam.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR11849:SF191; ECDYSONE-INDUCED PROTEIN 74EF ISOFORM B; 1.
DR PANTHER; PTHR11849; ETS; 1.
DR Pfam; PF00178; Ets; 1.
DR PRINTS; PR00454; ETSDOMAIN.
DR SMART; SM00413; ETS; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS00346; ETS_DOMAIN_2; 1.
DR PROSITE; PS50061; ETS_DOMAIN_3; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|RuleBase:RU004019};
KW Nucleus {ECO:0000256|RuleBase:RU004019}.
FT DOMAIN 397..449
FT /note="ETS"
FT /evidence="ECO:0000259|PROSITE:PS50061"
FT REGION 169..190
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 345..394
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 515 AA; 59373 MW; ADC1258F2A492A21 CRC64;
MDNSRNLLCE LFYKHLNDPN KHSLCNKLIM DELITTGKLL TQLHTEYNQI QQVTMFNYLY
QSLLSINFMD FNDHQMNSDL LNKFFNDLQM IQSSFHCYND KSCIQLLLLY YIHIIQLYQD
HINNNNMHKH NDDHYNLEQA EDLRVIVNKN HDISSIDLLG LSLSLPSSSS SSSSSTLSSS
LSSSSSPLSS LPIISSSKLD NDGDDNHDNN NSIHFTSIPS FISSDNYTMH YSIQPQQQQP
QQQQQPQQQL RNTPFTSIPI PIMNELSSFM TNSQHTFINN NKDNYNIHLL CNNQDVHYSM
NNQLNNSNEF NENRIKKLNC SNIQQLKSYT KKSLINMMRN KIGSNKCIRS SRRSSTDYKS
PLVPDQYQTN LSQDNNNNSD MLMSPDSPPT NKSQNMFKLV NSAAVAHLWG LHKHKPNMNY
ETMGRALRYY YAQNILRKVK GQRLVYQFLE DFHKTKHPIT TTTTISFTSS FMTTTITTTT
TSITKTIPTP VTITNRTIVT EFPENNSKPN IITLH
//
