ID   A0A094ZNN6_SCHHA        Unreviewed;        97 AA.
AC   A0A094ZNN6;
DT   26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT   26-NOV-2014, sequence version 1.
DT   28-JUN-2023, entry version 31.
DE   RecName: Full=26S proteasome non-ATPase regulatory subunit 13 {ECO:0000256|ARBA:ARBA00015732};
DE   AltName: Full=26S proteasome regulatory subunit RPN9 {ECO:0000256|ARBA:ARBA00029749};
DE   AltName: Full=26S proteasome regulatory subunit S11 {ECO:0000256|ARBA:ARBA00032323};
DE   AltName: Full=26S proteasome regulatory subunit p40.5 {ECO:0000256|ARBA:ARBA00031303};
GN   ORFNames=MS3_03990 {ECO:0000313|EMBL:KGB35722.1};
OS   Schistosoma haematobium (Blood fluke).
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Trematoda;
OC   Digenea; Strigeidida; Schistosomatoidea; Schistosomatidae; Schistosoma.
OX   NCBI_TaxID=6185 {ECO:0000313|EMBL:KGB35722.1};
RN   [1] {ECO:0000313|EMBL:KGB35722.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=22246508; DOI=10.1038/ng.1065;
RA   Young N.D., Jex A.R., Li B., Liu S., Yang L., Xiong Z., Li Y.,
RA   Cantacessi C., Hall R.S., Xu X., Chen F., Wu X., Zerlotini A., Oliveira G.,
RA   Hofmann A., Zhang G., Fang X., Kang Y., Campbell B.E., Loukas A.,
RA   Ranganathan S., Rollinson D., Rinaldi G., Brindley P.J., Yang H., Wang J.,
RA   Wang J., Gasser R.B.;
RT   "Whole-genome sequence of Schistosoma haematobium.";
RL   Nat. Genet. 44:221-225(2012).
CC   -!- FUNCTION: Component of the 26S proteasome, a multiprotein complex
CC       involved in the ATP-dependent degradation of ubiquitinated proteins.
CC       This complex plays a key role in the maintenance of protein homeostasis
CC       by removing misfolded or damaged proteins, which could impair cellular
CC       functions, and by removing proteins whose functions are no longer
CC       required. Therefore, the proteasome participates in numerous cellular
CC       processes, including cell cycle progression, apoptosis, or DNA damage
CC       repair. {ECO:0000256|ARBA:ARBA00002362}.
CC   -!- SUBUNIT: Component of the 19S proteasome regulatory particle complex.
CC       The 26S proteasome consists of a 20S core particle (CP) and two 19S
CC       regulatory subunits (RP). The regulatory particle is made of a lid
CC       composed of 9 subunits including PSMD13, a base containing 6 ATPases
CC       and few additional components. {ECO:0000256|ARBA:ARBA00011441}.
CC   -!- SIMILARITY: Belongs to the proteasome subunit S11 family.
CC       {ECO:0000256|ARBA:ARBA00006207}.
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DR   EMBL; KL250710; KGB35722.1; -; Genomic_DNA.
DR   RefSeq; XP_012795491.1; XM_012940037.1.
DR   AlphaFoldDB; A0A094ZNN6; -.
DR   STRING; 6185.A0A094ZNN6; -.
DR   GO; GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.
DR   InterPro; IPR000717; PCI_dom.
DR   InterPro; IPR035298; PSMD13.
DR   InterPro; IPR040798; Rpn9_C.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR10539; 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 13; 1.
DR   PANTHER; PTHR10539:SF0; 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 13; 1.
DR   Pfam; PF01399; PCI; 1.
DR   Pfam; PF18261; Rpn9_C; 1.
DR   SMART; SM00088; PINT; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR   PROSITE; PS50250; PCI; 1.
PE   3: Inferred from homology;
KW   Proteasome {ECO:0000313|EMBL:KGB35722.1}.
FT   DOMAIN          1..59
FT                   /note="PCI"
FT                   /evidence="ECO:0000259|PROSITE:PS50250"
SQ   SEQUENCE   97 AA;  11106 MW;  800A0E89264BCF2C CRC64;
     MVFRQPTNKR TLTFVEISST TRVPIDQVEH FLMKALSLKL IKGRIDEVNQ CVSLTWLQPR
     VLDKEQIGSM CARLKEWSST VEGMKNLVEV DTKSILA
//