ID A0A094ZR70_SCHHA Unreviewed; 777 AA.
AC A0A094ZR70;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 41.
DE SubName: Full=Potassium voltage-gated channel subfamily A member 2 {ECO:0000313|EMBL:KGB36657.1};
GN ORFNames=MS3_04971 {ECO:0000313|EMBL:KGB36657.1};
OS Schistosoma haematobium (Blood fluke).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Trematoda;
OC Digenea; Strigeidida; Schistosomatoidea; Schistosomatidae; Schistosoma.
OX NCBI_TaxID=6185 {ECO:0000313|EMBL:KGB36657.1};
RN [1] {ECO:0000313|EMBL:KGB36657.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=22246508; DOI=10.1038/ng.1065;
RA Young N.D., Jex A.R., Li B., Liu S., Yang L., Xiong Z., Li Y.,
RA Cantacessi C., Hall R.S., Xu X., Chen F., Wu X., Zerlotini A., Oliveira G.,
RA Hofmann A., Zhang G., Fang X., Kang Y., Campbell B.E., Loukas A.,
RA Ranganathan S., Rollinson D., Rinaldi G., Brindley P.J., Yang H., Wang J.,
RA Wang J., Gasser R.B.;
RT "Whole-genome sequence of Schistosoma haematobium.";
RL Nat. Genet. 44:221-225(2012).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; KL250798; KGB36657.1; -; Genomic_DNA.
DR RefSeq; XP_012796419.1; XM_012940965.1.
DR AlphaFoldDB; A0A094ZR70; -.
DR STRING; 6185.A0A094ZR70; -.
DR EnsemblMetazoa; XM_012940965.2; XP_012796419.2; MS3_0015413.
DR GeneID; 24592452; -.
DR KEGG; shx:MS3_00007540; -.
DR CTD; 24592452; -.
DR GO; GO:0008076; C:voltage-gated potassium channel complex; IEA:InterPro.
DR GO; GO:0022839; F:monoatomic ion-gated channel activity; IEA:UniProt.
DR GO; GO:0005249; F:voltage-gated potassium channel activity; IEA:InterPro.
DR GO; GO:0051260; P:protein homooligomerization; IEA:InterPro.
DR CDD; cd18377; BTB_POZ_Kv1_KCNA; 1.
DR Gene3D; 1.10.287.70; -; 1.
DR Gene3D; 1.20.120.350; Voltage-gated potassium channels. Chain C; 1.
DR InterPro; IPR000210; BTB/POZ_dom.
DR InterPro; IPR005821; Ion_trans_dom.
DR InterPro; IPR003968; K_chnl_volt-dep_Kv.
DR InterPro; IPR003972; K_chnl_volt-dep_Kv1.
DR InterPro; IPR011333; SKP1/BTB/POZ_sf.
DR InterPro; IPR003131; T1-type_BTB.
DR InterPro; IPR027359; Volt_channel_dom_sf.
DR PANTHER; PTHR11537:SF254; POTASSIUM VOLTAGE-GATED CHANNEL PROTEIN SHAKER; 1.
DR PANTHER; PTHR11537; VOLTAGE-GATED POTASSIUM CHANNEL; 1.
DR Pfam; PF02214; BTB_2; 1.
DR Pfam; PF00520; Ion_trans; 1.
DR PRINTS; PR00169; KCHANNEL.
DR PRINTS; PR01491; KVCHANNEL.
DR PRINTS; PR01496; SHAKERCHANEL.
DR SMART; SM00225; BTB; 1.
DR SUPFAM; SSF54695; POZ domain; 1.
DR SUPFAM; SSF81324; Voltage-gated potassium channels; 1.
PE 4: Predicted;
KW Ion channel {ECO:0000256|ARBA:ARBA00023303};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Potassium {ECO:0000256|ARBA:ARBA00022958};
KW Potassium channel {ECO:0000256|ARBA:ARBA00022826};
KW Potassium transport {ECO:0000256|ARBA:ARBA00022538};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448};
KW Voltage-gated channel {ECO:0000256|ARBA:ARBA00022882}.
FT TRANSMEM 533..558
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 578..598
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 610..631
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 679..700
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 741..761
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 407..507
FT /note="BTB"
FT /evidence="ECO:0000259|SMART:SM00225"
SQ SEQUENCE 777 AA; 89680 MW; 8CC3705346193EDD CRC64;
MLYTTSLMKV IPQTPKNIES DKFIFSSTPE ISHGTNRSRD FFGLIKRRPT NEKSIYSRHP
LYHHAPHCRH QQQHQRYHSH LRKQCPYRCI THKPSTSKSQ MAIHKSISKQ LSLPVEYTDE
QKSFYSSTGL LQTHSIMDDD IESGLNIHDD DLHSCVSIHK SNITIERPNS YHSGSSSTSL
TSCLRCLNSG QTVSSHTKAV DEINYDSEPQ CSRNSVTSNI SKLKYFDDTD TSNLFVNVQK
DTFKDRLLYF PTISNQLMLT NPTKRPFYSN HNNSDEIEKY DSTSAIDAKF SLPKKELKFA
VPEFLMPIID RRTSSQIFNV KQISASTLNI ENKLLKRRKT IKERFKQLHS DYDGSKFWNK
LNKNFKMNKV KNLSNTRSRS SMAISMDYTH HKDSVSRSSI TSCDDCRRIT INVSGLKFET
WLTVLERHPT TLLGDYNKRK PFYDEYRKEY FFDRHRPSFE AIFNYYQYGG RLKRPATVSD
DVFLTELEFF QIESEALDVY KKNEGYVPDI IVLPENLIKR KLWMLFEYPE TSILAFTFSM
ASFIFTVISI ILFCIETLPV YAQTHCEPGT RPNFRDPFFI IETLCTFWFT IEIFIRFISC
PSQKIFIKDI KNLIDLAAIV PYYITLFNVL ITFSCEGAKN SASLAFLRVI RLIRVFKLTK
HSSGLQVLVL TFKESIEGLS LFLVAFIVCI LVFSSTIYYV EIDRKGSQIE SIPDAFWWAV
ITMCTVGYGD KVPKGPLGKV VGSICAVAGV LTLAIPVPII TENFNKFYAH KTGRGRR
//
