ID A0A094ZRP0_SCHHA Unreviewed; 637 AA.
AC A0A094ZRP0;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE SubName: Full=Zinc finger CW-type PWWP domain protein 1 {ECO:0000313|EMBL:KGB37435.1};
GN ORFNames=MS3_0020629 {ECO:0000313|EMBL:KAF1337044.1}, MS3_05772
GN {ECO:0000313|EMBL:KGB37435.1};
OS Schistosoma haematobium (Blood fluke).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Trematoda;
OC Digenea; Strigeidida; Schistosomatoidea; Schistosomatidae; Schistosoma.
OX NCBI_TaxID=6185 {ECO:0000313|EMBL:KGB37435.1};
RN [1] {ECO:0000313|EMBL:KGB37435.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=22246508; DOI=10.1038/ng.1065;
RA Young N.D., Jex A.R., Li B., Liu S., Yang L., Xiong Z., Li Y.,
RA Cantacessi C., Hall R.S., Xu X., Chen F., Wu X., Zerlotini A., Oliveira G.,
RA Hofmann A., Zhang G., Fang X., Kang Y., Campbell B.E., Loukas A.,
RA Ranganathan S., Rollinson D., Rinaldi G., Brindley P.J., Yang H., Wang J.,
RA Wang J., Gasser R.B.;
RT "Whole-genome sequence of Schistosoma haematobium.";
RL Nat. Genet. 44:221-225(2012).
RN [2] {ECO:0000313|EMBL:KAF1337044.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=31494670;
RA Stroehlein A.J., Korhonen P.K., Chong T.M., Lim Y.L., Chan K.G.,
RA Webster B., Rollinson D., Brindley P.J., Gasser R.B., Young N.D.;
RT "High-quality Schistosoma haematobium genome achieved by single-molecule
RT and long-range sequencing.";
RL Gigascience 8:0-0(2019).
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AMPZ02000201; KAF1337044.1; -; Genomic_DNA.
DR EMBL; KL250884; KGB37435.1; -; Genomic_DNA.
DR RefSeq; XP_012797197.1; XM_012941743.1.
DR AlphaFoldDB; A0A094ZRP0; -.
DR EnsemblMetazoa; XM_012941743.1; XP_012797197.1; MS3_0020629.
DR OrthoDB; 5322065at2759; -.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR Gene3D; 2.30.30.140; -; 1.
DR Gene3D; 3.30.40.100; -; 1.
DR InterPro; IPR000313; PWWP_dom.
DR InterPro; IPR042778; ZCWPW1/ZCWPW2.
DR InterPro; IPR011124; Znf_CW.
DR PANTHER; PTHR15999; UNCHARACTERIZED; 1.
DR PANTHER; PTHR15999:SF2; ZINC FINGER CW-TYPE PWWP DOMAIN PROTEIN 1; 1.
DR Pfam; PF00855; PWWP; 1.
DR Pfam; PF07496; zf-CW; 1.
DR SMART; SM00293; PWWP; 1.
DR SUPFAM; SSF63748; Tudor/PWWP/MBT; 1.
DR PROSITE; PS50812; PWWP; 1.
DR PROSITE; PS51050; ZF_CW; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Signal {ECO:0000256|SAM:SignalP}; Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT SIGNAL 1..18
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 19..637
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5035986325"
FT DOMAIN 163..223
FT /note="CW-type"
FT /evidence="ECO:0000259|PROSITE:PS51050"
FT DOMAIN 242..307
FT /note="PWWP"
FT /evidence="ECO:0000259|PROSITE:PS50812"
FT REGION 108..133
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 108..126
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 637 AA; 73191 MW; FF351C0B34A9EFAF CRC64;
MLVGGNVLFL LSVIQLRGLN LMIICSRRLT MINVGDYFTS MLIILSEPPV ESLCEPNISN
FDKFLDETLD RISTVPLDIL YEKYFKYSRL EGNQSVTTDE IQYNETTSST FNFPSSSGNH
LKDISNGNNR KNNKKRSFKI SRSLVIGDAD STHCPRINII EKQDLPGTWV ECNFCSNWRY
LPKVYDPSQL NSSWSCTLNP KYFKRLTSNS TAKKCIHNPF EESEDLSAGK QGDQFIFEHF
SVGSVVWVKI QGYPDWPGMV CYNSQGRYAE FDASSREVTY YYVVFLNSKR LAMSKVPANR
IYKFITFNEV DLSKIPKRFW RRLQAAGQEA ENALLLSVKI FSQVKNSSGL YQEKSQTISN
EIKRKRVYKR KIPPIHSCSI NENSNRLTDY QLDTNSNHTS NMIPSSEEKL SNAIINGNTN
FHKVMPVSNH ISDNYNKESN NISLNNSSIE YQQLDLSLKS NLLVKSNNTT FDTQYNNTDI
NIDNDVLLND NTCQKMIKND KISSIDCYSP SFLKPIECDQ IMKEFICSID NCSNLNIETT
DIQMNNTIYL EQNNLSLNNY ENNKPKSNLI RNQNYFKLTY NDLLVYSNNV VANNNDIPMS
PVYSNKDTVE HLSLNSSKKI LYENVPFHYQ YFGSNEA
//
