ID A0A094ZVW5_SCHHA Unreviewed; 890 AA.
AC A0A094ZVW5;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 39.
DE RecName: Full=protein O-GlcNAc transferase {ECO:0000256|ARBA:ARBA00011970};
DE EC=2.4.1.255 {ECO:0000256|ARBA:ARBA00011970};
GN ORFNames=MS3_06840 {ECO:0000313|EMBL:KGB38452.1};
OS Schistosoma haematobium (Blood fluke).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Trematoda;
OC Digenea; Strigeidida; Schistosomatoidea; Schistosomatidae; Schistosoma.
OX NCBI_TaxID=6185 {ECO:0000313|EMBL:KGB38452.1};
RN [1] {ECO:0000313|EMBL:KGB38452.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=22246508; DOI=10.1038/ng.1065;
RA Young N.D., Jex A.R., Li B., Liu S., Yang L., Xiong Z., Li Y.,
RA Cantacessi C., Hall R.S., Xu X., Chen F., Wu X., Zerlotini A., Oliveira G.,
RA Hofmann A., Zhang G., Fang X., Kang Y., Campbell B.E., Loukas A.,
RA Ranganathan S., Rollinson D., Rinaldi G., Brindley P.J., Yang H., Wang J.,
RA Wang J., Gasser R.B.;
RT "Whole-genome sequence of Schistosoma haematobium.";
RL Nat. Genet. 44:221-225(2012).
CC -!- PATHWAY: Protein modification; protein glycosylation.
CC {ECO:0000256|ARBA:ARBA00004922}.
CC -!- SIMILARITY: Belongs to the glycosyltransferase 41 family. O-GlcNAc
CC transferase subfamily. {ECO:0000256|ARBA:ARBA00005386}.
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DR EMBL; KL251022; KGB38452.1; -; Genomic_DNA.
DR RefSeq; XP_012798213.1; XM_012942759.1.
DR AlphaFoldDB; A0A094ZVW5; -.
DR STRING; 6185.A0A094ZVW5; -.
DR UniPathway; UPA00378; -.
DR GO; GO:0097363; F:protein O-acetylglucosaminyltransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0006486; P:protein glycosylation; IEA:UniProtKB-UniPathway.
DR Gene3D; 3.30.720.150; -; 1.
DR Gene3D; 3.40.50.11380; -; 1.
DR Gene3D; 3.40.50.2000; Glycogen Phosphorylase B; 1.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 2.
DR InterPro; IPR029489; OGT/SEC/SPY_C.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR001440; TPR_1.
DR InterPro; IPR019734; TPR_repeat.
DR PANTHER; PTHR44366; UDP-N-ACETYLGLUCOSAMINE--PEPTIDE N-ACETYLGLUCOSAMINYLTRANSFERASE 110 KDA SUBUNIT; 1.
DR PANTHER; PTHR44366:SF1; UDP-N-ACETYLGLUCOSAMINE--PEPTIDE N-ACETYLGLUCOSAMINYLTRANSFERASE 110 KDA SUBUNIT; 1.
DR Pfam; PF13844; Glyco_transf_41; 1.
DR Pfam; PF00515; TPR_1; 2.
DR Pfam; PF13414; TPR_11; 3.
DR Pfam; PF13424; TPR_12; 1.
DR Pfam; PF13181; TPR_8; 1.
DR SMART; SM00028; TPR; 11.
DR SUPFAM; SSF48452; TPR-like; 2.
DR PROSITE; PS50005; TPR; 10.
DR PROSITE; PS50293; TPR_REGION; 4.
PE 3: Inferred from homology;
KW Glycosyltransferase {ECO:0000256|ARBA:ARBA00022676,
KW ECO:0000313|EMBL:KGB38452.1}; Repeat {ECO:0000256|ARBA:ARBA00022737};
KW TPR repeat {ECO:0000256|ARBA:ARBA00022803, ECO:0000256|PROSITE-
KW ProRule:PRU00339}; Transferase {ECO:0000313|EMBL:KGB38452.1}.
FT REPEAT 99..132
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 133..166
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 178..211
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 212..245
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 246..279
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 280..313
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 314..347
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 348..381
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 382..415
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 416..449
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT DOMAIN 463..870
FT /note="O-GlcNAc transferase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13844"
SQ SEQUENCE 890 AA; 99696 MW; C1ED1A7A46C1DDCF CRC64;
MATALNDILF RLSRSSSNMI ERRSILRLTD VSSLAELAHR EYQAGDYERA EQHCMQLWHQ
DPENTSTLLL LSSIHFQCRR MERSAYFSQL AIKQNPLMAE AYSNLGNVFK ERGQLKEAID
NYRHALRIKP DFIDGYINLA AALVAAGDME SAVNAYATAL QYNPSCYLKA IETCPTFAVA
WSNLGCVFNA QNEIWLAIHH FEKAVTLDPT FLDAYVNLGN VLKEARIFDR AVAAYLRALT
LSPNNAVVHG NLACVYYEQN LIDLAIDTYK RAIELQPNFP DAYCNLANAL KEKGKVSEAE
EYYNTALRLC PTHADSLNNL ANIKREQGKA EEAIRLYVRA LEIYPEFAVA HSNLASMLQL
QGKLQEALLH YREAIRISPT FADAYSNMGN TLKELQDVQG AMQCYQRAIQ INPAFADAHS
NLASILKDSG NLADAITSYK TALKLKPNFP DAFCNLAHCL QIVCDWSDYK HRMKKLVSMV
QDQLESNRLP SVHPHHSMLY PLTHDQRKKI AGKHASLCLE KVSLLHHQPF RFSKKLPAGQ
RLRIGYVSSD FCNHPTSHLM QSIPGLHDRT KVEVFCYSLA PDDGTNFRAK VANEAEHFVD
LSGIQCHGKA ADKIASDGIH ILLNMNGYTK GARNEIFALK PAPIQAMWLG YPGTSGSTFM
DYIITDMVTS PMHLSHQYSE KLAYMPKTFF IGDHQQMFPH LRNRVILESA EDATAGRRVT
DNSIVVSGLD IKPLLQVACV REVTYGGRLV EIHGSQRKEV SYFTKLTVLT IPSLQPIQNM
IRTNSPSCTI NGVTIHNGLV TQQTQSKASA GEEVPRDLIL TSRQHYGLPE DAVVFCNFNQ
LYKVDPSTMR MWVEILKGVP NSVLWLGRLP PPCGGRGRRA APAGESSNFI
//
