ID A0A095A0H1_SCHHA Unreviewed; 512 AA.
AC A0A095A0H1;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 41.
DE RecName: Full=NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial {ECO:0000256|ARBA:ARBA00015796};
DE AltName: Full=Vacuolar protein sorting-associated protein 72 homolog {ECO:0000256|ARBA:ARBA00020000};
GN ORFNames=MS3_07390 {ECO:0000313|EMBL:KGB38979.1};
OS Schistosoma haematobium (Blood fluke).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Trematoda;
OC Digenea; Strigeidida; Schistosomatoidea; Schistosomatidae; Schistosoma.
OX NCBI_TaxID=6185 {ECO:0000313|EMBL:KGB38979.1};
RN [1] {ECO:0000313|EMBL:KGB38979.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=22246508; DOI=10.1038/ng.1065;
RA Young N.D., Jex A.R., Li B., Liu S., Yang L., Xiong Z., Li Y.,
RA Cantacessi C., Hall R.S., Xu X., Chen F., Wu X., Zerlotini A., Oliveira G.,
RA Hofmann A., Zhang G., Fang X., Kang Y., Campbell B.E., Loukas A.,
RA Ranganathan S., Rollinson D., Rinaldi G., Brindley P.J., Yang H., Wang J.,
RA Wang J., Gasser R.B.;
RT "Whole-genome sequence of Schistosoma haematobium.";
RL Nat. Genet. 44:221-225(2012).
CC -!- SIMILARITY: Belongs to the VPS72/YL1 family.
CC {ECO:0000256|ARBA:ARBA00006832}.
CC -!- SIMILARITY: Belongs to the complex I NDUFS4 subunit family.
CC {ECO:0000256|ARBA:ARBA00005882}.
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DR EMBL; KL251111; KGB38979.1; -; Genomic_DNA.
DR RefSeq; XP_012798739.1; XM_012943285.1.
DR AlphaFoldDB; A0A095A0H1; -.
DR STRING; 6185.A0A095A0H1; -.
DR GO; GO:0005634; C:nucleus; IEA:InterPro.
DR GO; GO:0140849; F:ATP-dependent H2AZ histone chaperone activity; IEA:InterPro.
DR GO; GO:0022900; P:electron transport chain; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR Gene3D; 3.30.160.190; atu1810 like domain; 1.
DR InterPro; IPR006885; NADH_UbQ_FeS_4_mit-like.
DR InterPro; IPR038532; NDUFS4-like_sf.
DR InterPro; IPR008895; Vps72/YL1.
DR InterPro; IPR013272; Vps72/YL1_C.
DR InterPro; IPR046757; YL1_N.
DR PANTHER; PTHR13275:SF4; VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 72 HOMOLOG; 1.
DR PANTHER; PTHR13275; YL-1 PROTEIN TRANSCRIPTION FACTOR-LIKE 1; 1.
DR Pfam; PF04800; NDUS4; 1.
DR Pfam; PF05764; YL1; 1.
DR Pfam; PF08265; YL1_C; 1.
DR SMART; SM00993; YL1_C; 1.
PE 3: Inferred from homology;
KW Electron transport {ECO:0000256|ARBA:ARBA00022982};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Mitochondrion {ECO:0000256|ARBA:ARBA00023128};
KW Mitochondrion inner membrane {ECO:0000256|ARBA:ARBA00022792};
KW Respiratory chain {ECO:0000256|ARBA:ARBA00022660};
KW Transit peptide {ECO:0000256|ARBA:ARBA00022946};
KW Transport {ECO:0000256|ARBA:ARBA00022448};
KW Ubiquinone {ECO:0000313|EMBL:KGB38979.1}.
FT DOMAIN 458..487
FT /note="Vps72/YL1 C-terminal"
FT /evidence="ECO:0000259|SMART:SM00993"
FT REGION 220..258
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 220..243
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 244..258
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 512 AA; 58570 MW; 3C6C2C42B1F49548 CRC64;
MLLAKHIMKK SAEFSKDDVI TVPLEDDLTP INGVPKEHQS ERRVRIFIPA KPATQSGNHG
TRLWRIEFDN RERWENPLMG WASSGDPLST TVVEFETSEA AEEFCKRQGW PCYVESPNIL
KMNVKSYGSN FSWNKRTRQK VSFVLSISPL ILSKTLELTP KLSYPLNGMF WQLRLDSGPM
PISVDRERRE NAGARMARLL NEEEEDEFYS NIYGGFAEEP KRAKITRPQE NKLPDKKANS
DKSLTDSQSK STVQIKDKQQ QITITKKTSG QISTYERPEL RASTLQATAD QEAETTRRRI
ATAENTAVRR KALLAEIAQR KNLPEVRRLT QEELLAEAKI TEEINRRSLA RYQRLEIEKK
KARIQKTVNS TPMIRYHSFT VPIIEEQHNI YGVLASNDDE SSIRAGPIIT DHSAKCSRNL
ITFANDACFR DSMPETVTPL PEPGCPAPTP IRPERCLRIC PITGLPARYL DPLTLTPYAN
LAAFRVLRRL YSVHLETKKP PIELLREYRH GR
//
