ID A0A095A610_SCHHA Unreviewed; 250 AA.
AC A0A095A610;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 24-JAN-2024, entry version 35.
DE SubName: Full=Beta-1,4-galactosyltransferase 7 {ECO:0000313|EMBL:KGB42342.1};
DE SubName: Full=Putative beta-1, 4-galactosyltransferase {ECO:0000313|EMBL:KAF1337377.1};
GN ORFNames=MS3_0012808 {ECO:0000313|EMBL:KAF1337377.1}, MS3_11035
GN {ECO:0000313|EMBL:KGB42342.1};
OS Schistosoma haematobium (Blood fluke).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Trematoda;
OC Digenea; Strigeidida; Schistosomatoidea; Schistosomatidae; Schistosoma.
OX NCBI_TaxID=6185 {ECO:0000313|EMBL:KGB42342.1};
RN [1] {ECO:0000313|EMBL:KGB42342.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=22246508; DOI=10.1038/ng.1065;
RA Young N.D., Jex A.R., Li B., Liu S., Yang L., Xiong Z., Li Y.,
RA Cantacessi C., Hall R.S., Xu X., Chen F., Wu X., Zerlotini A., Oliveira G.,
RA Hofmann A., Zhang G., Fang X., Kang Y., Campbell B.E., Loukas A.,
RA Ranganathan S., Rollinson D., Rinaldi G., Brindley P.J., Yang H., Wang J.,
RA Wang J., Gasser R.B.;
RT "Whole-genome sequence of Schistosoma haematobium.";
RL Nat. Genet. 44:221-225(2012).
RN [2] {ECO:0000313|EMBL:KAF1337377.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=31494670;
RA Stroehlein A.J., Korhonen P.K., Chong T.M., Lim Y.L., Chan K.G.,
RA Webster B., Rollinson D., Brindley P.J., Gasser R.B., Young N.D.;
RT "High-quality Schistosoma haematobium genome achieved by single-molecule
RT and long-range sequencing.";
RL Gigascience 8:0-0(2019).
CC -!- PATHWAY: Protein modification; protein glycosylation.
CC {ECO:0000256|ARBA:ARBA00004922}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004606}; Single-
CC pass type II membrane protein {ECO:0000256|ARBA:ARBA00004606}.
CC -!- SIMILARITY: Belongs to the glycosyltransferase 7 family.
CC {ECO:0000256|ARBA:ARBA00005735}.
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DR EMBL; AMPZ02000145; KAF1337377.1; -; Genomic_DNA.
DR EMBL; KL252908; KGB42342.1; -; Genomic_DNA.
DR RefSeq; XP_012802262.1; XM_012946808.1.
DR AlphaFoldDB; A0A095A610; -.
DR STRING; 6185.A0A095A610; -.
DR EnsemblMetazoa; XM_012946808.1; XP_012802262.1; MS3_0012808.
DR OrthoDB; 306273at2759; -.
DR UniPathway; UPA00378; -.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016757; F:glycosyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR GO; GO:0006486; P:protein glycosylation; IEA:UniProtKB-UniPathway.
DR InterPro; IPR003859; Galactosyl_T.
DR InterPro; IPR027791; Galactosyl_T_C.
DR InterPro; IPR027995; Galactosyl_T_N.
DR InterPro; IPR029044; Nucleotide-diphossugar_trans.
DR PANTHER; PTHR19300; BETA-1,4-GALACTOSYLTRANSFERASE; 1.
DR PANTHER; PTHR19300:SF30; BETA-1,4-GALACTOSYLTRANSFERASE 7; 1.
DR Pfam; PF02709; Glyco_transf_7C; 1.
DR Pfam; PF13733; Glyco_transf_7N; 1.
DR PRINTS; PR02050; B14GALTRFASE.
DR SUPFAM; SSF53448; Nucleotide-diphospho-sugar transferases; 2.
PE 3: Inferred from homology;
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Glycosyltransferase {ECO:0000256|ARBA:ARBA00022676,
KW ECO:0000313|EMBL:KGB42342.1}; Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Signal {ECO:0000256|SAM:SignalP};
KW Signal-anchor {ECO:0000256|ARBA:ARBA00022968};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:KGB42342.1};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT SIGNAL 1..19
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 20..250
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5035986217"
FT DOMAIN 50..114
FT /note="Galactosyltransferase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF13733"
FT DOMAIN 182..235
FT /note="Galactosyltransferase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02709"
SQ SEQUENCE 250 AA; 29184 MW; 14C790CBD7D4DF76 CRC64;
MALCFFAAFL YFTKHYIVSD VIIRISDWKW GPADSQNCPV FDHSKEDLTI NRMAVLVPFR
DRFTELQEFI PHLNNFLNNQ NVRHTFFIIN QVDDLRFNRG ALLNVGALES LEAEVNGIIV
ESITQKNSLY QLSSQCLKLP FTKYLALHDV DLLPEDPALK YNMPSELGPI HLIPFYLHPR
YYYFKEYAGG VLIIKRTQYS LVGGMSNSFW GWGREDDEFQ IRLKSKGFKL MLVNSNWQIS
QQTLFSIVFY
//
