ID   A0A095AEK8_SCHHA        Unreviewed;      1022 AA.
AC   A0A095AEK8;
DT   26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT   26-NOV-2014, sequence version 1.
DT   27-MAR-2024, entry version 45.
DE   SubName: Full=Nuclear receptor subfamily 5 group A member 2 {ECO:0000313|EMBL:KGB32241.1};
DE   Flags: Fragment;
GN   ORFNames=MS3_00370 {ECO:0000313|EMBL:KGB32241.1};
OS   Schistosoma haematobium (Blood fluke).
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Trematoda;
OC   Digenea; Strigeidida; Schistosomatoidea; Schistosomatidae; Schistosoma.
OX   NCBI_TaxID=6185 {ECO:0000313|EMBL:KGB32241.1};
RN   [1] {ECO:0000313|EMBL:KGB32241.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=22246508; DOI=10.1038/ng.1065;
RA   Young N.D., Jex A.R., Li B., Liu S., Yang L., Xiong Z., Li Y.,
RA   Cantacessi C., Hall R.S., Xu X., Chen F., Wu X., Zerlotini A., Oliveira G.,
RA   Hofmann A., Zhang G., Fang X., Kang Y., Campbell B.E., Loukas A.,
RA   Ranganathan S., Rollinson D., Rinaldi G., Brindley P.J., Yang H., Wang J.,
RA   Wang J., Gasser R.B.;
RT   "Whole-genome sequence of Schistosoma haematobium.";
RL   Nat. Genet. 44:221-225(2012).
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR   EMBL; KL250496; KGB32241.1; -; Genomic_DNA.
DR   RefSeq; XP_012792019.1; XM_012936565.1.
DR   AlphaFoldDB; A0A095AEK8; -.
DR   STRING; 6185.A0A095AEK8; -.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0004879; F:nuclear receptor activity; IEA:InterPro.
DR   Gene3D; 1.10.565.10; Retinoid X Receptor; 1.
DR   InterPro; IPR035500; NHR-like_dom_sf.
DR   InterPro; IPR016355; NR5-like.
DR   InterPro; IPR000536; Nucl_hrmn_rcpt_lig-bd.
DR   InterPro; IPR001723; Nuclear_hrmn_rcpt.
DR   PANTHER; PTHR24086:SF15; NUCLEAR HORMONE RECEPTOR FTZ-F1; 1.
DR   PANTHER; PTHR24086; NUCLEAR RECEPTOR SUBFAMILY 5 GROUP A; 1.
DR   Pfam; PF00104; Hormone_recep; 1.
DR   PRINTS; PR00398; STRDHORMONER.
DR   SMART; SM00430; HOLI; 1.
DR   SUPFAM; SSF48508; Nuclear receptor ligand-binding domain; 1.
DR   PROSITE; PS51843; NR_LBD; 1.
PE   4: Predicted;
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW   Receptor {ECO:0000256|ARBA:ARBA00023170, ECO:0000313|EMBL:KGB32241.1};
KW   Transcription {ECO:0000256|ARBA:ARBA00023163};
KW   Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT   DOMAIN          489..806
FT                   /note="NR LBD"
FT                   /evidence="ECO:0000259|PROSITE:PS51843"
FT   REGION          113..162
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          191..282
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        124..162
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        191..247
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:KGB32241.1"
SQ   SEQUENCE   1022 AA;  113256 MW;  5123B6046C8FAE8B CRC64;
     KSTSNPSNSC LPFNFDKNNS SFLNDNGINN HLYSLTSSIH DSQYHQNIRQ QIKAPLIVPP
     SLLPSLPSLS NHPYPQLTNE HLMNTTTSHT QMMMNSTSIN QSNPTDFIET ESIKTERGES
     EGGGSSESEV SGDYGGVRTS DNLRSANNHN SNNNTYSTAS NTNNGSFELI NNELLTNKKY
     DCNIDEIPDD DYLTGDDTDG DDCTDSTVDD EEDTDYDEVD EYDDDDTEND IDDPDRDFDD
     EDREDDELSG GGCGVTSIGG AGGRDILEIS EGTGHSSFTC STSSYHKSEY ESESNHTGAT
     TSHLNTTISS TTTNTTNNNA NKVTNYGNDN EILFKNNPTT HANGFRFGQI FTTSVEHDYK
     VVEVVQKFIP KLKRSLFELC SFLKSENLEL TNSSTTTIPS SSSSTSLSRN EIINERINTE
     PVLMFRESSV GNFSNPILPL SPSSLVHESQ PHNNDIGSQV KSVSHFDSAE SSMPIFKNNK
     ANCFPTLGTS SPSTAQINEN STTIINLYLD DLLSSLCSLL ETCLFYLVDW MAQIESFKVL
     PVEDKMQLLN SSWSEIILLE FIHFYVTHLN NAKRTNTILT DSKRRCKNAM DPLNVCSSLF
     PINTNSINCN ENNPLTATTT TNITATAPTT SSSLLSHSSV SMEICDLIEN LLNNLLGGVD
     NCGGGQSDLK HKLNDLLTIF QKLQLDNKEF TCLKFIVLFN PLKHDTFLTS NLSYALKIQG
     KFCHFLLKRS RRFLRLINES SESQKLDHES PNELNTLLLP DRYGQILLEL AEVKFLAFQL
     ESFLLMRYRL GKIPNESLLS EMLLTKRSRV SLPVQPSYCN LMTSSMKSPP SITSSYVIPT
     CQFAYTNVNS KVIPIPSLST DADYRSNDEV IKHNQASSLC TNNLNNGTTM MVNATGSLST
     TPFTSPIPST FPLTSLHSPT SIPQFSNRNN NCNNNDASLL KNIDSQLSCT AFLNSYTNSP
     LYTPTTTNQL VYNHCFINND DHVITANNIN RFNEQLHESL STVTTMPATT TTTLVNHASI
     LS
//