ID A0A095AQ43_SCHHA Unreviewed; 795 AA.
AC A0A095AQ43;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 24-JAN-2024, entry version 33.
DE SubName: Full=E3 UFM1-protein ligase 1 {ECO:0000313|EMBL:KGB36426.1};
GN ORFNames=MS3_04720 {ECO:0000313|EMBL:KGB36426.1};
OS Schistosoma haematobium (Blood fluke).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Trematoda;
OC Digenea; Strigeidida; Schistosomatoidea; Schistosomatidae; Schistosoma.
OX NCBI_TaxID=6185 {ECO:0000313|EMBL:KGB36426.1};
RN [1] {ECO:0000313|EMBL:KGB36426.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=22246508; DOI=10.1038/ng.1065;
RA Young N.D., Jex A.R., Li B., Liu S., Yang L., Xiong Z., Li Y.,
RA Cantacessi C., Hall R.S., Xu X., Chen F., Wu X., Zerlotini A., Oliveira G.,
RA Hofmann A., Zhang G., Fang X., Kang Y., Campbell B.E., Loukas A.,
RA Ranganathan S., Rollinson D., Rinaldi G., Brindley P.J., Yang H., Wang J.,
RA Wang J., Gasser R.B.;
RT "Whole-genome sequence of Schistosoma haematobium.";
RL Nat. Genet. 44:221-225(2012).
CC -!- SIMILARITY: Belongs to the UFL1 family.
CC {ECO:0000256|ARBA:ARBA00010789}.
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DR EMBL; KL250774; KGB36426.1; -; Genomic_DNA.
DR RefSeq; XP_012796189.1; XM_012940735.1.
DR AlphaFoldDB; A0A095AQ43; -.
DR STRING; 6185.A0A095AQ43; -.
DR GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR GO; GO:0061666; F:UFM1 ligase activity; IEA:InterPro.
DR GO; GO:0071569; P:protein ufmylation; IEA:InterPro.
DR InterPro; IPR018611; Ufl1.
DR PANTHER; PTHR31057; E3 UFM1-PROTEIN LIGASE 1; 1.
DR PANTHER; PTHR31057:SF0; E3 UFM1-PROTEIN LIGASE 1; 1.
DR Pfam; PF09743; E3_UFM1_ligase; 1.
PE 3: Inferred from homology;
KW Ligase {ECO:0000313|EMBL:KGB36426.1};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT REGION 424..454
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 434..454
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 795 AA; 89252 MW; C16CA9B71FE0EECB CRC64;
MATWDEVRKL ANKLKETQNQ PNICKLSDRT WVDIIKHLMS VNRLKLVFST DGRSYLTRNE
LDKEIRDEVE AHSGRITLTE LASNLDVDFD IIESRVTELI TLDAQNKSPC RLISIPSEVV
NSSYVRRVAH EILDRLEEHG QTSIGELTVI FNLPTTFLSS IMQEYQSTLF HVHKYGEKYF
TDTFLNATKA KIRGYFTGVI RPVTLSSVAS KLQVPENLIN SIVSSLISTG RLYGNLIAGR
SGFVPKCYTY AEDTYINSFY SQNGYIEWNY LKRLNIPDPG SYLKTKLPNA MHLPGLTVNT
LIVDQLKSLI SGVIRDVSWI DLSHYIPNGL DSNERSALVN PLLKDAPVKL LDTYLIADKF
IESCEVFLDT YLKKKAQTAF HHEHHAILSS PTQQQSVEVN TPKQVVTSSK GGFGFGAREI
KTKNVKKKYN PSKRKTGNPS TTTDSENNFP SGIGDSQSLT KDLFARYVLM DDVRSILSSQ
LPNDVPSEMI DQVADMLEST LQQSFIKHIG SLISPNAGAN FDREKKLQTQ EVVNSMVLSL
QLLERGISSI NRDILRNQLL VHLLKNYESL SIESYHRLLE LLKHTSLPDA VSISSAIQQV
LDSFKVGQNN LTSLNAFYTS IKNLSVDVLG LTISVFHSSN SHNNKRERDE RLKANELAIQ
VEMQLKESVC DAKINNDLLK VATTATLAAT CLFAQIINGW PVTAPGKCVP ELIDWFCEAL
KFKTELESNS NEKSNSHITA LKTLQASNVL DDLSKLANYI SEKVRSGNVF EESDIQAHLK
HILDVGIQCR KQLYA
//
