ID A0A095B4B6_SCHHA Unreviewed; 504 AA.
AC A0A095B4B6;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE SubName: Full=Integrator complex subunit 11 {ECO:0000313|EMBL:KGB42056.1};
GN ORFNames=MS3_10639 {ECO:0000313|EMBL:KGB42056.1};
OS Schistosoma haematobium (Blood fluke).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Trematoda;
OC Digenea; Strigeidida; Schistosomatoidea; Schistosomatidae; Schistosoma.
OX NCBI_TaxID=6185 {ECO:0000313|EMBL:KGB42056.1};
RN [1] {ECO:0000313|EMBL:KGB42056.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=22246508; DOI=10.1038/ng.1065;
RA Young N.D., Jex A.R., Li B., Liu S., Yang L., Xiong Z., Li Y.,
RA Cantacessi C., Hall R.S., Xu X., Chen F., Wu X., Zerlotini A., Oliveira G.,
RA Hofmann A., Zhang G., Fang X., Kang Y., Campbell B.E., Loukas A.,
RA Ranganathan S., Rollinson D., Rinaldi G., Brindley P.J., Yang H., Wang J.,
RA Wang J., Gasser R.B.;
RT "Whole-genome sequence of Schistosoma haematobium.";
RL Nat. Genet. 44:221-225(2012).
CC -!- SIMILARITY: Belongs to the metallo-beta-lactamase superfamily. RNA-
CC metabolizing metallo-beta-lactamase-like family. INTS11 subfamily.
CC {ECO:0000256|ARBA:ARBA00007093}.
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DR EMBL; KL252372; KGB42056.1; -; Genomic_DNA.
DR RefSeq; XP_012801879.1; XM_012946425.1.
DR AlphaFoldDB; A0A095B4B6; -.
DR STRING; 6185.A0A095B4B6; -.
DR EnsemblMetazoa; XM_035733358.1; XP_035587283.1; MS3_0019031.
DR CDD; cd16291; INTS11-like_MBL-fold; 1.
DR Gene3D; 3.40.50.10890; -; 1.
DR Gene3D; 3.60.15.10; Ribonuclease Z/Hydroxyacylglutathione hydrolase-like; 1.
DR InterPro; IPR022712; Beta_Casp.
DR InterPro; IPR041897; INTS11-like_MBL-fold.
DR InterPro; IPR001279; Metallo-B-lactamas.
DR InterPro; IPR036866; RibonucZ/Hydroxyglut_hydro.
DR InterPro; IPR011108; RMMBL.
DR PANTHER; PTHR11203; CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR FAMILY MEMBER; 1.
DR PANTHER; PTHR11203:SF37; INTEGRATOR COMPLEX SUBUNIT 11; 1.
DR Pfam; PF10996; Beta-Casp; 1.
DR Pfam; PF16661; Lactamase_B_6; 1.
DR Pfam; PF07521; RMMBL; 1.
DR SMART; SM01027; Beta-Casp; 1.
DR SMART; SM00849; Lactamase_B; 1.
DR SUPFAM; SSF56281; Metallo-hydrolase/oxidoreductase; 1.
PE 3: Inferred from homology;
FT DOMAIN 16..246
FT /note="Metallo-beta-lactamase"
FT /evidence="ECO:0000259|SMART:SM00849"
FT DOMAIN 161..304
FT /note="Beta-Casp"
FT /evidence="ECO:0000259|SMART:SM01027"
SQ SEQUENCE 504 AA; 56620 MW; 5C1C4313565CE689 CRC64;
MSSIRVIPLG AGQDVGRSCI LVTLGGKNIM FDCGMHMGYN DDVSVHRNHV IDSFKRKFPD
FTYITDKGGL NDYLDCVIIS HFHLDHCGAL PYMTEVIGYD GPIYMTHPTK AICPILLEDY
RKINVERRGD QNFFTSDMIY RCMTKVRCVY IHQTVKVDDD LEIQAFYAGH VLGAAMFLVR
VGTNSVLYTG DYNMTPDRHL GAAWVSRCRP DLLITESTYA TTIRDSKRTR EREFLEKIHA
RVEAGGKPLG QGTVDNPGPM VVFATPGMLH AGQSLHIFRK WASDERNMVV IPGYCVAGTV
GYKILNGVRR LEFDKQVLEV KMSVEYLSFS AHADARGIMQ LISHCQPKHV MLVHGEAIKM
DFLKSKIEQE FGLPCSKPAN GEIVHVETEQ QFIVEASREF LNQSYYSDDP NEPLIKRPRS
IQGGIQIEPD ETPKLLDRAS VLASLSLKEH VMRFTSTYAF SSSSNLTTIL DKFIKLCSNP
RLEGDSYLIG LGLVNNFLAL VSLL
//
