ID A0A095BYE4_SCHHA Unreviewed; 454 AA.
AC A0A095BYE4;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 24-JAN-2024, entry version 40.
DE SubName: Full=Putative z-protein (S1r protein) {ECO:0000313|EMBL:KAF1330045.1};
DE SubName: Full=Regulator of G-protein signaling 6 {ECO:0000313|EMBL:KGB34148.1};
GN ORFNames=MS3_0013800 {ECO:0000313|EMBL:KAF1330045.1}, MS3_02351
GN {ECO:0000313|EMBL:KGB34148.1};
OS Schistosoma haematobium (Blood fluke).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Trematoda;
OC Digenea; Strigeidida; Schistosomatoidea; Schistosomatidae; Schistosoma.
OX NCBI_TaxID=6185 {ECO:0000313|EMBL:KGB34148.1};
RN [1] {ECO:0000313|EMBL:KGB34148.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=22246508; DOI=10.1038/ng.1065;
RA Young N.D., Jex A.R., Li B., Liu S., Yang L., Xiong Z., Li Y.,
RA Cantacessi C., Hall R.S., Xu X., Chen F., Wu X., Zerlotini A., Oliveira G.,
RA Hofmann A., Zhang G., Fang X., Kang Y., Campbell B.E., Loukas A.,
RA Ranganathan S., Rollinson D., Rinaldi G., Brindley P.J., Yang H., Wang J.,
RA Wang J., Gasser R.B.;
RT "Whole-genome sequence of Schistosoma haematobium.";
RL Nat. Genet. 44:221-225(2012).
RN [2] {ECO:0000313|EMBL:KAF1330045.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=31494670;
RA Stroehlein A.J., Korhonen P.K., Chong T.M., Lim Y.L., Chan K.G.,
RA Webster B., Rollinson D., Brindley P.J., Gasser R.B., Young N.D.;
RT "High-quality Schistosoma haematobium genome achieved by single-molecule
RT and long-range sequencing.";
RL Gigascience 8:0-0(2019).
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DR EMBL; AMPZ02000281; KAF1330045.1; -; Genomic_DNA.
DR EMBL; KL250591; KGB34148.1; -; Genomic_DNA.
DR RefSeq; XP_012793919.1; XM_012938465.1.
DR AlphaFoldDB; A0A095BYE4; -.
DR STRING; 6185.A0A095BYE4; -.
DR EnsemblMetazoa; XM_012938465.1; XP_012793919.1; MS3_0013800.
DR GeneID; 24590036; -.
DR KEGG; shx:MS3_00000113; -.
DR CTD; 24590036; -.
DR OrthoDB; 22856at2759; -.
DR GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR GO; GO:0009968; P:negative regulation of signal transduction; IEA:UniProtKB-KW.
DR GO; GO:0008277; P:regulation of G protein-coupled receptor signaling pathway; IEA:InterPro.
DR Gene3D; 1.10.1240.60; -; 1.
DR Gene3D; 1.10.167.10; Regulator of G-protein Signalling 4, domain 2; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR000591; DEP_dom.
DR InterPro; IPR016137; RGS.
DR InterPro; IPR047016; RGS6/7/9/11.
DR InterPro; IPR047017; RGS6/7/9/11_DHEX_sf.
DR InterPro; IPR040759; RGS_DHEX.
DR InterPro; IPR036305; RGS_sf.
DR InterPro; IPR044926; RGS_subdomain_2.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR45746; LP21163P; 1.
DR PANTHER; PTHR45746:SF5; REGULATOR OF G-PROTEIN SIGNALING 7-LIKE PROTEIN; 1.
DR Pfam; PF00610; DEP; 1.
DR Pfam; PF00615; RGS; 1.
DR Pfam; PF18148; RGS_DHEX; 1.
DR PRINTS; PR01301; RGSPROTEIN.
DR SMART; SM00049; DEP; 1.
DR SMART; SM00315; RGS; 1.
DR SUPFAM; SSF48097; Regulator of G-protein signaling, RGS; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50186; DEP; 1.
DR PROSITE; PS50132; RGS; 1.
PE 4: Predicted;
KW Signal transduction inhibitor {ECO:0000256|ARBA:ARBA00022700}.
FT DOMAIN 46..111
FT /note="DEP"
FT /evidence="ECO:0000259|PROSITE:PS50186"
FT DOMAIN 326..441
FT /note="RGS"
FT /evidence="ECO:0000259|PROSITE:PS50132"
SQ SEQUENCE 454 AA; 53687 MW; B0EDB7F023A21BC3 CRC64;
MSGMESLDLQ YRSLQTHKME QIIGQMNSKK TGITHEFQPD PYLHYAFQGG TIVSWLQENI
PTDNEQEALH MTELFLFYGY IFRITDSSQP YFKLNKTYWY RFQSPFYWLS KISKVDDIDY
SIYLMKKNLR KGGFQTTDPE NHIFTELSKS LNHKWKIIEL QAAEQLRLER KRDEVDRNIL
RLQEEAFWKV YRPMGKVKYR LTDALPRNFT LKQIQVRREQ MRNKMLEEKK QLEGQDVCSI
VPELQTDPLL SSHRGDKKSI ELIILYATNH VNYDNLINGD SMKNNWFASE KDTSVWEDDN
TVCSQTGVTG PAPYPTLKQV RLWGTSMNHL IRDENGQKWL EHFMQKEYSC ENFRFLQEVI
KYKFGPLSMI EKESKRIYAE YLAKTGASEI NIDNYIMTVT EELLKNPNPF CFDLAQEHIY
NLVRTDSYAR FLRSSDYLTL LNNAMKAAST HQTK
//
