ID A0A095C232_CRYGR Unreviewed; 432 AA.
AC A0A095C232;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 24-JAN-2024, entry version 33.
DE RecName: Full=W2 domain-containing protein {ECO:0000259|PROSITE:PS51363};
GN ORFNames=CNBG_0838 {ECO:0000313|EMBL:KGB75000.1};
OS Cryptococcus gattii serotype B (strain R265) (Filobasidiella gattii)
OS (Cryptococcus bacillisporus).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Tremellomycetes;
OC Tremellales; Cryptococcaceae; Cryptococcus;
OC Cryptococcus gattii species complex.
OX NCBI_TaxID=294750 {ECO:0000313|EMBL:KGB75000.1, ECO:0000313|Proteomes:UP000029445};
RN [1] {ECO:0000313|EMBL:KGB75000.1, ECO:0000313|Proteomes:UP000029445}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=R265 {ECO:0000313|EMBL:KGB75000.1};
RX PubMed=21304167; DOI=10.1128/mBio.00342-10;
RA D'Souza C.A., Kronstad J.W., Taylor G., Warren R., Yuen M., Hu G.,
RA Jung W.H., Sham A., Kidd S.E., Tangen K., Lee N., Zeilmaker T., Sawkins J.,
RA McVicker G., Shah S., Gnerre S., Griggs A., Zeng Q., Bartlett K., Li W.,
RA Wang X., Heitman J., Stajich J.E., Fraser J.A., Meyer W., Carter D.,
RA Schein J., Krzywinski M., Kwon-Chung K.J., Varma A., Wang J., Brunham R.,
RA Fyfe M., Ouellette B.F., Siddiqui A., Marra M., Jones S., Holt R.,
RA Birren B.W., Galagan J.E., Cuomo C.A.;
RT "Genome variation in Cryptococcus gattii, an emerging pathogen of
RT immunocompetent hosts.";
RL MBio 2:E342-E342(2011).
RN [2] {ECO:0000313|EMBL:KGB75000.1, ECO:0000313|Proteomes:UP000029445}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=R265 {ECO:0000313|EMBL:KGB75000.1};
RX PubMed=29507212;
RA Yadav V., Sun S., Billmyre R.B., Thimmappa B.C., Shea T., Lintner R.,
RA Bakkeren G., Cuomo C.A., Heitman J., Sanyal K.;
RT "RNAi is a critical determinant of centromere evolution in closely related
RT fungi.";
RL Proc. Natl. Acad. Sci. 115:3108-3113(2018).
CC -!- SIMILARITY: Belongs to the BZW family. {ECO:0000256|ARBA:ARBA00008151}.
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DR EMBL; CP025760; KGB75000.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A095C232; -.
DR STRING; 294750.A0A095C232; -.
DR VEuPathDB; FungiDB:CNBG_0838; -.
DR HOGENOM; CLU_032849_2_1_1; -.
DR OMA; ELIQCIW; -.
DR Proteomes; UP000029445; Chromosome 2.
DR CDD; cd11560; W2_eIF5C_like; 1.
DR Gene3D; 1.25.40.180; -; 1.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR043510; W2_BZW1/2.
DR InterPro; IPR003307; W2_domain.
DR PANTHER; PTHR14208; BASIC LEUCINE ZIPPER AND W2 DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR14208:SF2; PROTEIN KRASAVIETZ; 1.
DR Pfam; PF02020; W2; 1.
DR SMART; SM00515; eIF5C; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR PROSITE; PS51363; W2; 1.
PE 3: Inferred from homology;
FT DOMAIN 265..432
FT /note="W2"
FT /evidence="ECO:0000259|PROSITE:PS51363"
FT REGION 1..30
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 432 AA; 48807 MW; 5C3D770185D14056 CRC64;
MSHTPTSTAP GTAPTADKKP SLTGVRIKQR KGQAKATAKF EPEAFRDALL LHLALLPHPI
TKDALVAKLV QAGSTLEFLK YSEQLFELLF VGGLLQPGGS YLDDKRSPVY ILQPDDAPDA
FNDGVKGMIE VLKRVMQRYK YLQKPLEENF LPGVLSYLPK WDVRSREKLA EATALLTIEL
QISSRCLQSL AKEHVVKDNV ALNFLTAFIK TYLSRQSIDQ FGSTLRRSGL KSILAVFPLQ
IRDRKHLEAH FREENLQVVN DWYAKLALGE IKDETVQAVE RMINDDETSD QIIEALKLQQ
SERPVSEVDL SEWIWIALMG TVDWTARSDQ IDTFVISHIT RYASILETFC QSAKAQVNLI
NAVQVYCYTD TRIIKSFVQI LKVLYNADVV SDQAIIYWHQ KGAKPNGKGH FLKVAEPLVK
FLSEQESDSE EE
//
