ID A0A095C338_SCHHA Unreviewed; 2581 AA.
AC A0A095C338;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 24-JAN-2024, entry version 31.
DE SubName: Full=Bromodomain adjacent to zinc finger domain protein 2A {ECO:0000313|EMBL:KGB36118.1};
GN ORFNames=MS3_04400 {ECO:0000313|EMBL:KGB36118.1};
OS Schistosoma haematobium (Blood fluke).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Trematoda;
OC Digenea; Strigeidida; Schistosomatoidea; Schistosomatidae; Schistosoma.
OX NCBI_TaxID=6185 {ECO:0000313|EMBL:KGB36118.1};
RN [1] {ECO:0000313|EMBL:KGB36118.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=22246508; DOI=10.1038/ng.1065;
RA Young N.D., Jex A.R., Li B., Liu S., Yang L., Xiong Z., Li Y.,
RA Cantacessi C., Hall R.S., Xu X., Chen F., Wu X., Zerlotini A., Oliveira G.,
RA Hofmann A., Zhang G., Fang X., Kang Y., Campbell B.E., Loukas A.,
RA Ranganathan S., Rollinson D., Rinaldi G., Brindley P.J., Yang H., Wang J.,
RA Wang J., Gasser R.B.;
RT "Whole-genome sequence of Schistosoma haematobium.";
RL Nat. Genet. 44:221-225(2012).
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DR EMBL; KL250746; KGB36118.1; -; Genomic_DNA.
DR RefSeq; XP_012795883.1; XM_012940429.1.
DR STRING; 6185.A0A095C338; -.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR Gene3D; 1.20.920.10; Bromodomain-like; 1.
DR InterPro; IPR001487; Bromodomain.
DR InterPro; IPR036427; Bromodomain-like_sf.
DR InterPro; IPR018501; DDT_dom.
DR PANTHER; PTHR45915:SF2; IP14655P-RELATED; 1.
DR PANTHER; PTHR45915; TRANSCRIPTION INTERMEDIARY FACTOR; 1.
DR Pfam; PF00439; Bromodomain; 1.
DR Pfam; PF02791; DDT; 1.
DR PRINTS; PR00503; BROMODOMAIN.
DR SMART; SM00297; BROMO; 1.
DR SMART; SM00571; DDT; 1.
DR SUPFAM; SSF47370; Bromodomain; 1.
DR PROSITE; PS50014; BROMODOMAIN_2; 1.
DR PROSITE; PS50827; DDT; 1.
PE 4: Predicted;
KW Bromodomain {ECO:0000256|PROSITE-ProRule:PRU00035};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242}.
FT DOMAIN 940..1005
FT /note="DDT"
FT /evidence="ECO:0000259|PROSITE:PS50827"
FT DOMAIN 2436..2507
FT /note="Bromo"
FT /evidence="ECO:0000259|PROSITE:PS50014"
FT REGION 1..23
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 366..405
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 428..525
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2301..2362
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 1177..1211
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1748..1775
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 428..486
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 495..509
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2316..2344
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2581 AA; 292553 MW; 40470E3BD4067DB9 CRC64;
MSSISNTYTS SGRDADKTTS NDKNCSSFEL PFMSAQPSTL LNGNTPCVNP SLSYLNGLNY
WSQKSFPNTE VHSFPTNTNF LPYLDDQQKL QQLQMQLLLM EQSGKEPQSV TKEHRIFGNK
MEYLSGTNVN VPNHNILSGS QNMNFWNNLR MLPEMLAYTN PIIKETQNTS SGLSIQDIQQ
LAFLNQIYNQ LNTGQSNSFN VNSISQSNTL VTDIPGINIP GNYHPTTISS QDVTLTDLSS
KSNPSIHFTN NDNSILAGQI FNNFCNLQAE NQKQRQNNIY FSDNISDTLK YSNPIPLNST
TSTNELYCSS GSVNPMILNT SVPASNNITS LNDKTSISSA NSLAYAQALM MIMNAMYGSY
KTGQTSVQND QPNGLNLPQS GLFNYNTNQQ SINSPTVTST PLNTEPKESF NDVLTFLGQC
LNSSTSYNDK TLSHRQQNTS VKQSQQVTNL SCSKSTTTKK LSGRQRTTSR NHQSDQPTTS
TTTHRGRGRP PKLAGVQYQT QSKQQQHKRN QLTAHNDRQP QDNTEGNLAV VSDSISHCDQ
NCSQMKPEFI MSFSKPKGNA HGVTDMNDLN MFPGSMCFSE SKIKIEPDSQ EKKLLSTTTD
RNESSVEETI DDVLKSIADC KGDLATLASQ LAYSTLGITS NKQFCKDQTE VDNNDSYTNN
PSLISHGQSS SHVPIHSEWN LQDVTKNVRQ ISMLGGVMFL NALGHDLCNQ NNPQDKAPNT
TGNYFNQSEF TETNLNNCAS STKCNLNTVV DSKVCLPQIG SQTEMKSICD TSYSFCPSEE
KINSSIAPTY SSLTPTSSFM DPNQVKMFPY HVSQVHPKTD MCLNNTKNQE VPVQNQQLYQ
PTNEKTHHGL YNGTSENILK STSLSSSDDN YSHLSSNTTN SLYQQNSAEK EYLKNFFIEF
VKQQEQLQKE KDEFIKEEQK QLKEMPLPKL DSIPGNRMTR KMFGNCLMII EFLHAFSDVL
CIDPEIIPNM GELQSALIDR NPQCQRFLVH LVIGLLKLAV EDPGLPSPRL ITQLLGQKFN
EIELNEQTIS IILRVFIISR NGYEDDMSDW LHPPIQFIDL TGEQQASLLA FICDELICSS
RLISTEIDRT IEQQSLLKRE KWIIESKIRR LRLLIAQKLT ITGNLINNTI TEYDRKAIDM
EPTGYQKNMP LTTLPKLTSM PIVSNSCAIS STSLSDDEDS TCKISELEAK IESLTRKTEQ
KQREIDECSS RLSGLFLGQD RYYSNYYVLK HMGGIYIECE SPGNMSTKSD CCVESLTTES
GENPILPIDS TLSELPDSHL DHIVNQIKVR RELAQQRQLK LTVSIANSYP CHDIPFENKL
HSNFEKLQLD GNSHAAILNQ TEQCDINPET ILNDVQLKNS DHLNGKDVIE TVNENVCPRS
PNCVHISHPD NEKIVENSDD PSCIKDSSGI YSNYDVKNIS EDINCESLAQ IPDNNPSELS
TKKYPVIIVP KYPTESHSTQ DDNISFQSLG SCIDDTNGPV GFVYNHISHK DDAEESTNQS
KNDFEIKSNV SHDGICDSSM NPIPLNKVDG VECKEELKVK ISTPLINHDN ITKDTMINRD
NVKLEDNNRQ TNGQDCHDRL VNEISPYKLE SFTYKTYTLG QPLDLSNKPL HSEPFSNENL
NHETLPTEFK SDLDDLTLTK SVMLFMNHAG INLPTVDNQL YSDSWISIMN YCKFLLSSAI
SDEMVYSKSS NSDNVSLLNL PLKESIVKLR EMMLNQFKTE PLNETQMINE QNNNHYQLDI
DITECVNNEL ENRRIQTMKE NLSCLKLKND NIQSNWYELV DINKLKDLLD ALNCRGVREK
QLAKCIRRSK DFIELSMHVA LKRNSDYDVV KSLPTTKLNS RLMQIRTHRR RGRRSGRGHG
TTKMSSGFYY TGGGSWNCLS GKTSNGFISS SSWEGNNSSE SKEIERLHSS TSNISRSDIL
CSSDDGSSDT NSGLTVTSLA GSKRTLVDMC RGYHNLSLTS TVNPIEIISS KYKIFDNKGL
KWEDNSTEYE NFMSECQLLY DVEALEDKII YASLQTKEWK IPNKTSEDEI ISLIPRTEVK
KSRFEHWPLE LARDRLLDIE RHIERRYLLP PFNSEVHLNI IPEVETTDVP FLPEVRSNTE
STDTGIETEG ECNDIKYDRC EFNTEIVEDD INVSGQNHVP QIRHVTNKQS NSNDPVDTSN
ACDYQLDSNR PDGLNGPIHD QTSNNIPQDL MDWRTNLNQA SDINTIRSCM NQLVLAIAWD
KSIMKVKSRR KRKVYEDTDV NNNQMLKRSK MCSALKLEHP SMNSYDALSI VDSKFINPNR
KYQGWWRKVH KYRKRTENID SGTIPITKSK IRKYKPRSHT DLENKRRRPN ASEEFNEFPL
RKKPGRKPTY HLNTLPTKPK RHYHRRSILL VSKNISGSRG RPRRRCRTLH QEITNGNDDK
SSTIDSTESI QPLCQTYQSM KSNELEWCRR ATEDLLNHEA SWAFRKPVNL KQVPIYRKII
KHPMDLSTIW RKVQDPAAYT TFSNWVHDVR LIFSNCEFFN EDDSEVGRAG HAMRAYFESR
WSKFDEKVNL NGHEVDDESK SQKELIATNS VPERLIAICE DTTETKHLNT MSVQSTSGTE
N
//
