ID   A0A095C3F0_CRYGR        Unreviewed;       275 AA.
AC   A0A095C3F0;
DT   26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT   26-NOV-2014, sequence version 1.
DT   24-JAN-2024, entry version 29.
DE   SubName: Full=Carboxymethylenebutenolidase {ECO:0000313|EMBL:KGB75430.1};
GN   ORFNames=CNBG_1268 {ECO:0000313|EMBL:KGB75430.1};
OS   Cryptococcus gattii serotype B (strain R265) (Filobasidiella gattii)
OS   (Cryptococcus bacillisporus).
OC   Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Tremellomycetes;
OC   Tremellales; Cryptococcaceae; Cryptococcus;
OC   Cryptococcus gattii species complex.
OX   NCBI_TaxID=294750 {ECO:0000313|EMBL:KGB75430.1, ECO:0000313|Proteomes:UP000029445};
RN   [1] {ECO:0000313|EMBL:KGB75430.1, ECO:0000313|Proteomes:UP000029445}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=R265 {ECO:0000313|EMBL:KGB75430.1};
RX   PubMed=21304167; DOI=10.1128/mBio.00342-10;
RA   D'Souza C.A., Kronstad J.W., Taylor G., Warren R., Yuen M., Hu G.,
RA   Jung W.H., Sham A., Kidd S.E., Tangen K., Lee N., Zeilmaker T., Sawkins J.,
RA   McVicker G., Shah S., Gnerre S., Griggs A., Zeng Q., Bartlett K., Li W.,
RA   Wang X., Heitman J., Stajich J.E., Fraser J.A., Meyer W., Carter D.,
RA   Schein J., Krzywinski M., Kwon-Chung K.J., Varma A., Wang J., Brunham R.,
RA   Fyfe M., Ouellette B.F., Siddiqui A., Marra M., Jones S., Holt R.,
RA   Birren B.W., Galagan J.E., Cuomo C.A.;
RT   "Genome variation in Cryptococcus gattii, an emerging pathogen of
RT   immunocompetent hosts.";
RL   MBio 2:E342-E342(2011).
RN   [2] {ECO:0000313|EMBL:KGB75430.1, ECO:0000313|Proteomes:UP000029445}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=R265 {ECO:0000313|EMBL:KGB75430.1};
RX   PubMed=29507212;
RA   Yadav V., Sun S., Billmyre R.B., Thimmappa B.C., Shea T., Lintner R.,
RA   Bakkeren G., Cuomo C.A., Heitman J., Sanyal K.;
RT   "RNAi is a critical determinant of centromere evolution in closely related
RT   fungi.";
RL   Proc. Natl. Acad. Sci. 115:3108-3113(2018).
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DR   EMBL; CP025761; KGB75430.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A095C3F0; -.
DR   STRING; 294750.A0A095C3F0; -.
DR   VEuPathDB; FungiDB:CNBG_1268; -.
DR   HOGENOM; CLU_054590_1_0_1; -.
DR   OMA; CATCFFP; -.
DR   Proteomes; UP000029445; Chromosome 3.
DR   GO; GO:0016787; F:hydrolase activity; IEA:InterPro.
DR   Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR   InterPro; IPR029058; AB_hydrolase.
DR   InterPro; IPR002925; Dienelactn_hydro.
DR   PANTHER; PTHR47562; -; 1.
DR   PANTHER; PTHR47562:SF2; CARBOXYMETHYLENEBUTENOLIDASE-RELATED; 1.
DR   Pfam; PF01738; DLH; 1.
DR   SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
PE   4: Predicted;
FT   DOMAIN          35..255
FT                   /note="Dienelactone hydrolase"
FT                   /evidence="ECO:0000259|Pfam:PF01738"
SQ   SEQUENCE   275 AA;  30124 MW;  7A37168A63C0401F CRC64;
     MLIKTSYRDV PTTANGKSGT IRIYLVEPSL PGYPKARFPG CVVFSEIYQV TGPVERFASN
     IASEGYIVAL PSSFHEFEGP EPIPYDSEGT DRGNCYKVEK TVEAYDEDAT LSIDLLVSLP
     NCTGRIASTG MCLGGHLALR CAFDPRVQAT FCYFATDVHS ATLGKGKSDD TLVKIRKGDL
     TGKGEVAMVF GKQDTHVDRD GRSLIRDTLD AANVTFTFLE VQAQHAFIRD ESSKGRWDAA
     LSRSLFGMMM ELFNRRVARD LGEPTGDGAK IEHVC
//