ID A0A095C579_SCHHA Unreviewed; 201 AA.
AC A0A095C579;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE SubName: Full=Zinc transporter 6-A {ECO:0000313|EMBL:KGB37043.1};
DE Flags: Fragment;
GN ORFNames=MS3_05373 {ECO:0000313|EMBL:KGB37043.1};
OS Schistosoma haematobium (Blood fluke).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Trematoda;
OC Digenea; Strigeidida; Schistosomatoidea; Schistosomatidae; Schistosoma.
OX NCBI_TaxID=6185 {ECO:0000313|EMBL:KGB37043.1};
RN [1] {ECO:0000313|EMBL:KGB37043.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=22246508; DOI=10.1038/ng.1065;
RA Young N.D., Jex A.R., Li B., Liu S., Yang L., Xiong Z., Li Y.,
RA Cantacessi C., Hall R.S., Xu X., Chen F., Wu X., Zerlotini A., Oliveira G.,
RA Hofmann A., Zhang G., Fang X., Kang Y., Campbell B.E., Loukas A.,
RA Ranganathan S., Rollinson D., Rinaldi G., Brindley P.J., Yang H., Wang J.,
RA Wang J., Gasser R.B.;
RT "Whole-genome sequence of Schistosoma haematobium.";
RL Nat. Genet. 44:221-225(2012).
CC -!- SUBUNIT: Heterodimer with SLC30A5; form a functional zinc ion
CC transmembrane transporter. {ECO:0000256|ARBA:ARBA00038600}.
CC -!- SUBCELLULAR LOCATION: Golgi apparatus, trans-Golgi network membrane
CC {ECO:0000256|ARBA:ARBA00004166}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004166}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; KL250839; KGB37043.1; -; Genomic_DNA.
DR RefSeq; XP_012796805.1; XM_012941351.1.
DR AlphaFoldDB; A0A095C579; -.
DR STRING; 6185.A0A095C579; -.
DR GO; GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008324; F:monoatomic cation transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0006829; P:zinc ion transport; IEA:UniProtKB-KW.
DR Gene3D; 1.20.1510.10; Cation efflux protein transmembrane domain; 1.
DR InterPro; IPR002524; Cation_efflux.
DR InterPro; IPR027469; Cation_efflux_TMD_sf.
DR PANTHER; PTHR46531; ZINC TRANSPORTER 6; 1.
DR PANTHER; PTHR46531:SF1; ZINC TRANSPORTER 6; 1.
DR Pfam; PF01545; Cation_efflux; 1.
DR SUPFAM; SSF161111; Cation efflux protein transmembrane domain-like; 1.
PE 4: Predicted;
KW Ion transport {ECO:0000256|ARBA:ARBA00022906};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448};
KW Zinc {ECO:0000256|ARBA:ARBA00022906};
KW Zinc transport {ECO:0000256|ARBA:ARBA00022906}.
FT TRANSMEM 6..23
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 43..59
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 79..97
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 143..161
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 181..200
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KGB37043.1"
SQ SEQUENCE 201 AA; 22424 MW; FCF26C0A49C6B13D CRC64;
LTAFTHLLIF DLLSVIVALI SFWTNRKKAS IESYSLGYER FEVVAVFAST ILAILLSFFE
IKEAVERIFE PAEISSNHML TPCLIAFGVH LLSVYGIDNM AFAHVIQACG SSWLQEHTTD
ISRTICRIIP GLSRVLLPRV NPISLIGVST TTTVCIVYLI LINMSKKSQH INFPDPLPDT
LGGIIISLML FGTMMPMMLY R
//
