ID A0A095CBT2_CRYGR Unreviewed; 465 AA.
AC A0A095CBT2;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 44.
DE SubName: Full=Solute carrier family 35 (UDP-xylose/UDP-N-acetylglucosamine transporter) member B4 {ECO:0000313|EMBL:KGB77980.1};
GN ORFNames=CNBG_4067 {ECO:0000313|EMBL:KGB77980.1};
OS Cryptococcus gattii serotype B (strain R265) (Filobasidiella gattii)
OS (Cryptococcus bacillisporus).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Tremellomycetes;
OC Tremellales; Cryptococcaceae; Cryptococcus;
OC Cryptococcus gattii species complex.
OX NCBI_TaxID=294750 {ECO:0000313|EMBL:KGB77980.1, ECO:0000313|Proteomes:UP000029445};
RN [1] {ECO:0000313|EMBL:KGB77980.1, ECO:0000313|Proteomes:UP000029445}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=R265 {ECO:0000313|EMBL:KGB77980.1};
RX PubMed=21304167; DOI=10.1128/mBio.00342-10;
RA D'Souza C.A., Kronstad J.W., Taylor G., Warren R., Yuen M., Hu G.,
RA Jung W.H., Sham A., Kidd S.E., Tangen K., Lee N., Zeilmaker T., Sawkins J.,
RA McVicker G., Shah S., Gnerre S., Griggs A., Zeng Q., Bartlett K., Li W.,
RA Wang X., Heitman J., Stajich J.E., Fraser J.A., Meyer W., Carter D.,
RA Schein J., Krzywinski M., Kwon-Chung K.J., Varma A., Wang J., Brunham R.,
RA Fyfe M., Ouellette B.F., Siddiqui A., Marra M., Jones S., Holt R.,
RA Birren B.W., Galagan J.E., Cuomo C.A.;
RT "Genome variation in Cryptococcus gattii, an emerging pathogen of
RT immunocompetent hosts.";
RL MBio 2:E342-E342(2011).
RN [2] {ECO:0000313|EMBL:KGB77980.1, ECO:0000313|Proteomes:UP000029445}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=R265 {ECO:0000313|EMBL:KGB77980.1};
RX PubMed=29507212;
RA Yadav V., Sun S., Billmyre R.B., Thimmappa B.C., Shea T., Lintner R.,
RA Bakkeren G., Cuomo C.A., Heitman J., Sanyal K.;
RT "RNAi is a critical determinant of centromere evolution in closely related
RT fungi.";
RL Proc. Natl. Acad. Sci. 115:3108-3113(2018).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; CP025764; KGB77980.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A095CBT2; -.
DR STRING; 294750.A0A095CBT2; -.
DR VEuPathDB; FungiDB:CNBG_4067; -.
DR HOGENOM; CLU_033007_0_0_1; -.
DR OMA; NPFTGWH; -.
DR Proteomes; UP000029445; Chromosome 6.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008643; P:carbohydrate transport; IEA:UniProtKB-KW.
DR GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
DR InterPro; IPR013657; SCL35B1-4/HUT1.
DR NCBIfam; TIGR00803; nst; 1.
DR PANTHER; PTHR10778; SOLUTE CARRIER FAMILY 35 MEMBER B; 1.
DR PANTHER; PTHR10778:SF4; UDP-XYLOSE AND UDP-N-ACETYLGLUCOSAMINE TRANSPORTER; 1.
DR Pfam; PF08449; UAA; 1.
DR SUPFAM; SSF103481; Multidrug resistance efflux transporter EmrE; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Sugar transport {ECO:0000256|ARBA:ARBA00022597};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius};
KW Transport {ECO:0000256|ARBA:ARBA00022597}.
FT TRANSMEM 18..36
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 91..109
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 115..136
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 143..163
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 195..215
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 227..246
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 297..318
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 382..465
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 406..426
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 465 AA; 50987 MW; F15C40EC309417EE CRC64;
MTDPGLISSF LQTTAGEWFM ILSLVFGGCC SNVWALEGVL KDHPKSGTFL TFSQFVFVAL
QNLSSQVELA RSRSGVIYPK LKTRNVPLKR WIIQVILFFA VSLMNNYAFG LKIPVTLHII
FRSGGLCVSM IVGRVIGKRR YSIAQMLAGL LITIGIIIAT LSAPHRQSSR SSDTVSTMDE
STGQPTSWMA HERDYIAGIA LLAGALFLSA LLGLYQEHTY RLYGKQWKEA LFYGHFLSLP
LFTPFYSDLI QTYSAYTSSP SLALLSIPRP SASLFPALFT ETPTSFSSTK YFDWHELLIP
SAMFALALNL ITQGLCVRGV NRLTTRVNSV TVNMVLTVRK AVSLVISVWY YGSGVTWSLV
IGGGMVLLGT ILYSLAPGPK GLGPSPSDKD KPIPTPKTET SSRPRPILVE QKKGDAIGDQ
WEDAEITRAG NDSNLQSDPL VSAGLRYRQS PMEGSAMEKN ATKSR
//
