ID A0A095DGB2_CRYGR Unreviewed; 449 AA.
AC A0A095DGB2;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE RecName: Full=SET domain-containing protein 5 {ECO:0000256|ARBA:ARBA00042380};
GN ORFNames=CNBG_5574 {ECO:0000313|EMBL:KGB79736.1};
OS Cryptococcus gattii serotype B (strain R265) (Filobasidiella gattii)
OS (Cryptococcus bacillisporus).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Tremellomycetes;
OC Tremellales; Cryptococcaceae; Cryptococcus;
OC Cryptococcus gattii species complex.
OX NCBI_TaxID=294750 {ECO:0000313|EMBL:KGB79736.1, ECO:0000313|Proteomes:UP000029445};
RN [1] {ECO:0000313|EMBL:KGB79736.1, ECO:0000313|Proteomes:UP000029445}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=R265 {ECO:0000313|EMBL:KGB79736.1};
RX PubMed=21304167; DOI=10.1128/mBio.00342-10;
RA D'Souza C.A., Kronstad J.W., Taylor G., Warren R., Yuen M., Hu G.,
RA Jung W.H., Sham A., Kidd S.E., Tangen K., Lee N., Zeilmaker T., Sawkins J.,
RA McVicker G., Shah S., Gnerre S., Griggs A., Zeng Q., Bartlett K., Li W.,
RA Wang X., Heitman J., Stajich J.E., Fraser J.A., Meyer W., Carter D.,
RA Schein J., Krzywinski M., Kwon-Chung K.J., Varma A., Wang J., Brunham R.,
RA Fyfe M., Ouellette B.F., Siddiqui A., Marra M., Jones S., Holt R.,
RA Birren B.W., Galagan J.E., Cuomo C.A.;
RT "Genome variation in Cryptococcus gattii, an emerging pathogen of
RT immunocompetent hosts.";
RL MBio 2:E342-E342(2011).
RN [2] {ECO:0000313|EMBL:KGB79736.1, ECO:0000313|Proteomes:UP000029445}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=R265 {ECO:0000313|EMBL:KGB79736.1};
RX PubMed=29507212;
RA Yadav V., Sun S., Billmyre R.B., Thimmappa B.C., Shea T., Lintner R.,
RA Bakkeren G., Cuomo C.A., Heitman J., Sanyal K.;
RT "RNAi is a critical determinant of centromere evolution in closely related
RT fungi.";
RL Proc. Natl. Acad. Sci. 115:3108-3113(2018).
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DR EMBL; CP025761; KGB79736.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A095DGB2; -.
DR STRING; 294750.A0A095DGB2; -.
DR VEuPathDB; FungiDB:CNBG_5574; -.
DR HOGENOM; CLU_031650_0_0_1; -.
DR OMA; CEPNVRY; -.
DR Proteomes; UP000029445; Chromosome 3.
DR GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR CDD; cd20071; SET_SMYD; 1.
DR Gene3D; 1.10.220.160; -; 1.
DR Gene3D; 6.10.140.2220; -; 1.
DR Gene3D; 2.170.270.10; SET domain; 1.
DR InterPro; IPR001214; SET_dom.
DR InterPro; IPR046341; SET_dom_sf.
DR PANTHER; PTHR46402:SF2; HISTONE-LYSINE N-TRIMETHYLTRANSFERASE SMYD5; 1.
DR PANTHER; PTHR46402; SET AND MYND DOMAIN-CONTAINING PROTEIN 5; 1.
DR Pfam; PF00856; SET; 1.
DR SUPFAM; SSF82199; SET domain; 1.
DR PROSITE; PS50280; SET; 1.
PE 4: Predicted;
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 93..410
FT /note="SET"
FT /evidence="ECO:0000259|PROSITE:PS50280"
SQ SEQUENCE 449 AA; 50763 MW; B8319E54FF617034 CRC64;
MTDLTAEAAI SPSDDILLPA LASLRENHPD KGILKLLAQL KVDHPEWAVS EKRFRKALQL
APSPGDGEAD PSEKALVADT GLDPSIDVKS IAPKVEVKMF AGGKGKGLVA KEGLKQGEML
WQEEPWIVTS DPGHYSLLTQ SMMCSQCFSL FARPSPPLSV PCPHCITAHF CNRLCYTKSL
SSSHLPLLCP GLNPDASSLM DFIRKRGERS VEGVAKILAR WRGEREWGAK GKAEEMEKRI
WKGMARVSQK RKEMERREWS YISKARMEEW HLIHIMLINV LNPSPTHENY KSFQRLLISQ
HPRRFRPVPL TEKEVKRWFS FESFLELLGL VGLNQEDSGG LYALHAHLNH SCEPNIQVRN
LPKSYTPPTQ ETLPVDLPPP IQAGDKVSNK LTILARHGIQ PGEELTISYV NMKMPRDERR
QALREGYGFW CACDRCVREK ERPNGEKNE
//
