ID A0A095S8N5_9GAMM Unreviewed; 370 AA.
AC A0A095S8N5;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE RecName: Full=3-hydroxyisobutyryl-CoA hydrolase {ECO:0000256|ARBA:ARBA00011915};
DE EC=3.1.2.4 {ECO:0000256|ARBA:ARBA00011915};
GN ORFNames=T9A_01866 {ECO:0000313|EMBL:KGD61006.1};
OS Alcanivorax jadensis T9.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Oceanospirillales;
OC Alcanivoracaceae; Alcanivorax.
OX NCBI_TaxID=1177181 {ECO:0000313|EMBL:KGD61006.1, ECO:0000313|Proteomes:UP000029443};
RN [1] {ECO:0000313|EMBL:KGD61006.1, ECO:0000313|Proteomes:UP000029443}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=T9 {ECO:0000313|EMBL:KGD61006.1,
RC ECO:0000313|Proteomes:UP000029443};
RA Lai Q., Shao Z.;
RT "Genome Sequence of alkane-degrading Bacterium Alcanivorax jadensis T9.";
RL Submitted (SEP-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=3-hydroxy-2-methylpropanoyl-CoA + H2O = 3-hydroxy-2-
CC methylpropanoate + CoA + H(+); Xref=Rhea:RHEA:20888,
CC ChEBI:CHEBI:11805, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:57287, ChEBI:CHEBI:57340; EC=3.1.2.4;
CC Evidence={ECO:0000256|ARBA:ARBA00001709};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KGD61006.1}.
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DR EMBL; ARXU01000006; KGD61006.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A095S8N5; -.
DR STRING; 1177181.T9A_01866; -.
DR PATRIC; fig|1177181.3.peg.1861; -.
DR eggNOG; COG1024; Bacteria.
DR Proteomes; UP000029443; Unassembled WGS sequence.
DR GO; GO:0003860; F:3-hydroxyisobutyryl-CoA hydrolase activity; IEA:InterPro.
DR CDD; cd06558; crotonase-like; 1.
DR InterPro; IPR029045; ClpP/crotonase-like_dom_sf.
DR InterPro; IPR045004; ECH_dom.
DR InterPro; IPR032259; HIBYL-CoA-H.
DR PANTHER; PTHR43176:SF3; 3-HYDROXYISOBUTYRYL-COA HYDROLASE, MITOCHONDRIAL; 1.
DR PANTHER; PTHR43176; 3-HYDROXYISOBUTYRYL-COA HYDROLASE-RELATED; 1.
DR Pfam; PF16113; ECH_2; 1.
DR SUPFAM; SSF52096; ClpP/crotonase; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801}.
FT DOMAIN 19..356
FT /note="Enoyl-CoA hydratase/isomerase"
FT /evidence="ECO:0000259|Pfam:PF16113"
SQ SEQUENCE 370 AA; 40960 MW; 2EBEA7C742B4956C CRC64;
MSDCVLFSEI ETRCGRVIAR ATLNAPKALN ALSLDMIQVL SKQMDEWEQR DDVVAIWLEG
AGGKAFCAGG DIVQMHKSMV KHAGQGRNPF TEQYFAEEYA LDYRIHTSRI PVVVFGDGIV
MGGGMGLLQG ADFRLVTPRS RMAMPEITIG LFPDVGGSWF LNRLPGRVGL FLGLTGVHIN
GREAVEIGMA DRMVDGDADN LLAALAEQDF ADDATDNRAV LYRLFKQQAA DMSELNQPLI
DHLPQINRLC DGESLPVVVE QLLSAKDRDA WLDKALGNLE RGCPQTAHLV WEQLARSTYL
SLADIFRMEW CLAVQCSLHG DFREGVRALL IDKDGSPGFR HRSVNDVPRE YIDGFFECPA
PKHPLEAIDS
//
