ID A0A095SIZ6_9GAMM Unreviewed; 302 AA.
AC A0A095SIZ6;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE RecName: Full=6-carboxy-5,6,7,8-tetrahydropterin synthase {ECO:0000256|ARBA:ARBA00018141};
DE EC=4.1.2.50 {ECO:0000256|ARBA:ARBA00012982};
DE AltName: Full=Queuosine biosynthesis protein QueD {ECO:0000256|ARBA:ARBA00031449};
GN ORFNames=Y5S_02307 {ECO:0000313|EMBL:KGD64552.1};
OS Alcanivorax nanhaiticus.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Oceanospirillales;
OC Alcanivoracaceae; Alcanivorax.
OX NCBI_TaxID=1177154 {ECO:0000313|EMBL:KGD64552.1, ECO:0000313|Proteomes:UP000029444};
RN [1] {ECO:0000313|EMBL:KGD64552.1, ECO:0000313|Proteomes:UP000029444}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=19-m-6 {ECO:0000313|EMBL:KGD64552.1,
RC ECO:0000313|Proteomes:UP000029444};
RA Lai Q., Shao Z.;
RT "Genome Sequence of alkane-degrading Bacterium Alcanivorax sp. 19-m-6.";
RL Submitted (SEP-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=7,8-dihydroneopterin 3'-triphosphate + H2O = 6-
CC carboxy-5,6,7,8-tetrahydropterin + acetaldehyde + 2 H(+) +
CC triphosphate; Xref=Rhea:RHEA:27966, ChEBI:CHEBI:15343,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:18036,
CC ChEBI:CHEBI:58462, ChEBI:CHEBI:61032; EC=4.1.2.50;
CC Evidence={ECO:0000256|ARBA:ARBA00001293};
CC -!- PATHWAY: Purine metabolism; 7-cyano-7-deazaguanine biosynthesis.
CC {ECO:0000256|ARBA:ARBA00005061}.
CC -!- SIMILARITY: Belongs to the PTPS family. QueD subfamily.
CC {ECO:0000256|ARBA:ARBA00008900}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KGD64552.1}.
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DR EMBL; ARXV01000008; KGD64552.1; -; Genomic_DNA.
DR RefSeq; WP_035233135.1; NZ_ARXV01000008.1.
DR AlphaFoldDB; A0A095SIZ6; -.
DR STRING; 1177154.Y5S_02307; -.
DR PATRIC; fig|1177154.3.peg.2347; -.
DR eggNOG; COG0720; Bacteria.
DR OrthoDB; 5820615at2; -.
DR UniPathway; UPA00391; -.
DR Proteomes; UP000029444; Unassembled WGS sequence.
DR GO; GO:0070497; F:6-carboxy-5,6,7,8-tetrahydropterin synthase activity; IEA:UniProtKB-EC.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR Gene3D; 3.30.479.10; 6-pyruvoyl tetrahydropterin synthase/QueD; 2.
DR InterPro; IPR007115; 6-PTP_synth/QueD.
DR InterPro; IPR038418; 6-PTP_synth/QueD_sf.
DR Pfam; PF01242; PTPS; 2.
DR SUPFAM; SSF55620; Tetrahydrobiopterin biosynthesis enzymes-like; 2.
PE 3: Inferred from homology;
SQ SEQUENCE 302 AA; 34372 MW; 0AF7999964893F36 CRC64;
MATLFVENLT VADFSFLHSK RGMVGESWLV DLELTGDLDH QGMVFDFGHI KKRIKQAIDE
RVDHRLLVPV DCDQASVVER DNDTSLEWQY RGGTIRMVVP SESLLLMPGT EVSKASLTLH
LMELVQSVVP ENVHEVRIIL REEDTGTAPY YHYSHGLKKH DGNCQRIAHG HRSNIHIFEN
GRRSRYWEKL WADRWEDIYL GTREDLEGTY YIDEIPHHRF RYDAPQGHFE LVIPEDHCYL
IDTDSTVEQL AAHIAEQLAE EAPGKHFRVR AFEGVGKGAI AEAGENLPGK AHSGWLSGAA
VI
//
