ID A0A095ST78_9FLAO Unreviewed; 996 AA.
AC A0A095ST78;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 24-JAN-2024, entry version 30.
DE RecName: Full=beta-N-acetylhexosaminidase {ECO:0000256|ARBA:ARBA00012663};
DE EC=3.2.1.52 {ECO:0000256|ARBA:ARBA00012663};
GN ORFNames=LG45_12155 {ECO:0000313|EMBL:KGD67861.1};
OS Flavobacterium aquatile LMG 4008 = ATCC 11947.
OC Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales;
OC Flavobacteriaceae; Flavobacterium.
OX NCBI_TaxID=1453498 {ECO:0000313|EMBL:KGD67861.1, ECO:0000313|Proteomes:UP000029554};
RN [1] {ECO:0000313|EMBL:KGD67861.1, ECO:0000313|Proteomes:UP000029554}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LMG 4008 {ECO:0000313|EMBL:KGD67861.1,
RC ECO:0000313|Proteomes:UP000029554};
RA Gale A.N., Pipes S.E., Newman J.D.;
RT "Whole Genome Shotgun of Flavobacterium aquatile LMG 4008.";
RL Submitted (SEP-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Hydrolysis of terminal non-reducing N-acetyl-D-hexosamine
CC residues in N-acetyl-beta-D-hexosaminides.; EC=3.2.1.52;
CC Evidence={ECO:0000256|ARBA:ARBA00001231};
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 3 family.
CC {ECO:0000256|ARBA:ARBA00005336, ECO:0000256|RuleBase:RU361161}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KGD67861.1}.
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DR EMBL; JRHH01000004; KGD67861.1; -; Genomic_DNA.
DR RefSeq; WP_035127443.1; NZ_MUGQ01000007.1.
DR AlphaFoldDB; A0A095ST78; -.
DR STRING; 1453498.LG45_12155; -.
DR eggNOG; COG1472; Bacteria.
DR eggNOG; COG1680; Bacteria.
DR OrthoDB; 9805821at2; -.
DR Proteomes; UP000029554; Unassembled WGS sequence.
DR GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR Gene3D; 3.40.50.1700; Glycoside hydrolase family 3 C-terminal domain; 1.
DR Gene3D; 3.20.20.300; Glycoside hydrolase, family 3, N-terminal domain; 1.
DR InterPro; IPR001466; Beta-lactam-related.
DR InterPro; IPR012338; Beta-lactam/transpept-like.
DR InterPro; IPR019800; Glyco_hydro_3_AS.
DR InterPro; IPR002772; Glyco_hydro_3_C.
DR InterPro; IPR036881; Glyco_hydro_3_C_sf.
DR InterPro; IPR001764; Glyco_hydro_3_N.
DR InterPro; IPR036962; Glyco_hydro_3_N_sf.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR PANTHER; PTHR30480:SF13; BETA-HEXOSAMINIDASE; 1.
DR PANTHER; PTHR30480; BETA-HEXOSAMINIDASE-RELATED; 1.
DR Pfam; PF00144; Beta-lactamase; 1.
DR Pfam; PF00933; Glyco_hydro_3; 1.
DR Pfam; PF01915; Glyco_hydro_3_C; 1.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF52279; Beta-D-glucan exohydrolase, C-terminal domain; 1.
DR SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
DR PROSITE; PS00775; GLYCOSYL_HYDROL_F3; 1.
PE 3: Inferred from homology;
KW Glycosidase {ECO:0000256|RuleBase:RU361161};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU361161};
KW Reference proteome {ECO:0000313|Proteomes:UP000029554};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..21
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 22..996
FT /note="beta-N-acetylhexosaminidase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5001917963"
FT DOMAIN 74..387
FT /note="Glycoside hydrolase family 3 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00933"
FT DOMAIN 427..580
FT /note="Glycoside hydrolase family 3 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF01915"
FT DOMAIN 619..972
FT /note="Beta-lactamase-related"
FT /evidence="ECO:0000259|Pfam:PF00144"
SQ SEQUENCE 996 AA; 112298 MW; 9A81268B00736DFE CRC64;
MKNLIKLFSF LLLITFLTNC SSSKDKTSKK LKKPNSVVED IYVPHLKSDR KTFFKGSLAE
DKWVDSVYNQ MPFNEKVGQL FMVAAYSNKD SVHVNGLDKL ISDYKIGGLI FFQGGPVRQA
KLTNRFQSKS KLPLFIGIDA EWGLSMRLDS TYKFPWNSTL GAIRDLKLIE KMGEQLGKES
KRMGIHFNFA PVLDINTNPK NPIIGHRSFG EDKVNVTDRA IALMTGVQNQ GVFATGKHFP
GHGDTATDSH YALPLVNFSR ERLENVELYP YKRMFDEGLE SVMVAHLNVP SLEARPKVPT
SLSYNVVTDL LKKEMAFDGL IFTDALNMKA ASNFKKPGDI DLEALLAGND ILLFAENVPV
AVEKITAAYN EGLVTDERLA YSVKKILHYK YKIGLNKYKP IDETNLMSDI NPSSNTALQY
ELFENAITLL KNDNAILPIK ELDKKIAYVK LGDDTNAKFL STLKKYTDVT EVTSDNIDSL
NVQLKNFDIV IVGFHKSDKA WKKHDFTETE LLWLQEIAKN NKVILDIFAK AYSLLPITTF
DDIESVIVSY QNGDIPQEVS AELIFGAVDA KGKLPVSIND FFRVNDGLSS EKINRIGFTA
PENVGMSSSK LATIETIAQK AIDEKMAPGM QILVARKGKV IYQKSFGYHT YENLTKVQNS
DIYDVASITK MVSTLPNVMQ LYDQGKVTLD TKLGEMLPIF QGSDKQDITF KELLSHYARL
QAWLPFYKET LDADNCPADR FYSLTYKDGY TKQVAENLFI NDNYKDVILK KIVDSKLSDK
KEYKYSDFTF IILKEYLEKI TGKSLDILSA HNFYNMLGMS NTMYNPLRKF DMRIIPPTDN
DTYFRHTTIQ GYVHDMEAAM EGGIAGHAGI FSNAMDVAKM MQMYLNKGNY GGIQYFSNAT
FDVFNTCHFC TEGNRRGLGF DKPQLGKEGP TCGCVSMSSF GHTGFTGTMA WADPETEIIY
VFLSNRTFPD SNASNKLSKE NIREDIQKII QEAIIK
//
