ID A0A095XGE5_9FIRM Unreviewed; 271 AA.
AC A0A095XGE5;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 24-JAN-2024, entry version 28.
DE RecName: Full=Pur operon repressor {ECO:0000256|ARBA:ARBA00018449};
GN ORFNames=HMPREF1635_06125 {ECO:0000313|EMBL:KGF08766.1};
OS Clostridiales bacterium S5-A14a.
OC Bacteria; Bacillota; Clostridia; Eubacteriales;
OC Eubacteriales Family XIII. Incertae Sedis.
OX NCBI_TaxID=1230734 {ECO:0000313|EMBL:KGF08766.1, ECO:0000313|Proteomes:UP000029601};
RN [1] {ECO:0000313|EMBL:KGF08766.1, ECO:0000313|Proteomes:UP000029601}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=S5-A14a {ECO:0000313|EMBL:KGF08766.1,
RC ECO:0000313|Proteomes:UP000029601};
RA McCorrison J., Sanka R., Torralba M., Gillis M., Haft D.H., Methe B.,
RA Sutton G., Nelson K.E.;
RL Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the purine/pyrimidine phosphoribosyltransferase
CC family. {ECO:0000256|ARBA:ARBA00008391}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KGF08766.1}.
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DR EMBL; JRNA01000017; KGF08766.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A095XGE5; -.
DR STRING; 1230734.HMPREF1635_06125; -.
DR Proteomes; UP000029601; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0045892; P:negative regulation of DNA-templated transcription; IEA:InterPro.
DR GO; GO:0045982; P:negative regulation of purine nucleobase metabolic process; IEA:InterPro.
DR CDD; cd06223; PRTases_typeI; 1.
DR Gene3D; 3.40.50.2020; -; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR000836; PRibTrfase_dom.
DR InterPro; IPR029057; PRTase-like.
DR InterPro; IPR015265; PuR_N.
DR InterPro; IPR010078; PurR_Bsub.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR NCBIfam; TIGR01743; purR_Bsub; 1.
DR PANTHER; PTHR43864; HYPOXANTHINE/GUANINE PHOSPHORIBOSYLTRANSFERASE; 1.
DR PANTHER; PTHR43864:SF2; PUR OPERON REPRESSOR; 1.
DR Pfam; PF00156; Pribosyltran; 1.
DR Pfam; PF09182; PuR_N; 1.
DR SUPFAM; SSF53271; PRTase-like; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Reference proteome {ECO:0000313|Proteomes:UP000029601};
KW Repressor {ECO:0000256|ARBA:ARBA00022491}.
FT DOMAIN 4..73
FT /note="Bacterial purine repressor N-terminal"
FT /evidence="ECO:0000259|Pfam:PF09182"
FT DOMAIN 115..264
FT /note="Phosphoribosyltransferase"
FT /evidence="ECO:0000259|Pfam:PF00156"
SQ SEQUENCE 271 AA; 30090 MW; 86BDA26919129D01 CRC64;
MSVKRSMRIS SMLQEMTSRP SNIFNFKYFC DRYDIAKSTV SEDVSIANEA LEISGQGELV
TIPGSLGGVK YIPTINKKMS KIVQDEFCSR LTDSSRILGG GFLYTSDIMY DVSFVKNLGR
IFITKFKDIE ADYIVTVETK GIPLASTIAY MLNLPLVIIR REPKFSEGST VSINYFSGPD
QRVQKMSIAK RAVKPGSKAI VIDDFMRGGG SIKGIREILN EFEVETVATG IAIISSKPQN
KKVDSFVHLV TLEEVDDFEK TISVSPNVSI F
//
