ID   A0A095Y6T5_9BACT        Unreviewed;       969 AA.
AC   A0A095Y6T5;
DT   26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT   26-NOV-2014, sequence version 1.
DT   27-MAR-2024, entry version 29.
DE   SubName: Full=Peptidase M16 {ECO:0000313|EMBL:KGF17983.1};
GN   ORFNames=HMPREF1640_05515 {ECO:0000313|EMBL:KGF17983.1};
OS   Prevotella sp. S7-1-8.
OC   Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Prevotellaceae;
OC   Prevotella.
OX   NCBI_TaxID=1284775 {ECO:0000313|EMBL:KGF17983.1, ECO:0000313|Proteomes:UP000029597};
RN   [1] {ECO:0000313|EMBL:KGF17983.1, ECO:0000313|Proteomes:UP000029597}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=S7-1-8 {ECO:0000313|EMBL:KGF17983.1,
RC   ECO:0000313|Proteomes:UP000029597};
RA   McCorrison J., Sanka R., Torralba M., Gillis M., Haft D.H., Methe B.,
RA   Sutton G., Nelson K.E.;
RL   Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the peptidase M16 family.
CC       {ECO:0000256|ARBA:ARBA00007261, ECO:0000256|RuleBase:RU004447}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KGF17983.1}.
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DR   EMBL; JRNC01000031; KGF17983.1; -; Genomic_DNA.
DR   RefSeq; WP_036892880.1; NZ_JRNC01000031.1.
DR   AlphaFoldDB; A0A095Y6T5; -.
DR   eggNOG; COG0612; Bacteria.
DR   OrthoDB; 9811314at2; -.
DR   Proteomes; UP000029597; Unassembled WGS sequence.
DR   GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR   GO; GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
DR   GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.830.10; Metalloenzyme, LuxS/M16 peptidase-like; 4.
DR   InterPro; IPR011249; Metalloenz_LuxS/M16.
DR   InterPro; IPR011765; Pept_M16_N.
DR   InterPro; IPR001431; Pept_M16_Zn_BS.
DR   InterPro; IPR007863; Peptidase_M16_C.
DR   PANTHER; PTHR43690; NARDILYSIN; 1.
DR   PANTHER; PTHR43690:SF17; PROTEIN YHJJ; 1.
DR   Pfam; PF00675; Peptidase_M16; 1.
DR   Pfam; PF05193; Peptidase_M16_C; 2.
DR   SUPFAM; SSF63411; LuxS/MPP-like metallohydrolase; 4.
DR   PROSITE; PS00143; INSULINASE; 1.
PE   3: Inferred from homology;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Metalloprotease {ECO:0000256|ARBA:ARBA00023049};
KW   Protease {ECO:0000256|ARBA:ARBA00022670};
KW   Reference proteome {ECO:0000313|Proteomes:UP000029597};
KW   Signal {ECO:0000256|SAM:SignalP}; Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT   SIGNAL          1..20
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           21..969
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5001913353"
FT   DOMAIN          49..99
FT                   /note="Peptidase M16 N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF00675"
FT   DOMAIN          251..424
FT                   /note="Peptidase M16 C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF05193"
FT   DOMAIN          713..877
FT                   /note="Peptidase M16 C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF05193"
SQ   SEQUENCE   969 AA;  110268 MW;  7D2A5FF3449295DE CRC64;
     MKFKLITASL ATFLALTISA KDYHYKSVAG DPMQTRIYTL DNGLKVYLSV NKEKPRLQTY
     IAVRTGSRND PAETTGLAHY LEHLMFKGTK LYGTSDALAE APLLDEIEQR YEDYRRLKDP
     VSRKNAYHEI DSVSQIAAKY NIPNEYDKIM RSIGAEGTNA YTSNDVTCYV NDIPANEIES
     WAKVESDRFR NMVIRGFHTE LEAVYEEFNI GLANDSRKMW EAMFKKLFPT HPYGTQSTIG
     TQEHLKNPSI TNIKNYFNRY YVPNNIAICM AGDIDPDKVM AIIDKYFGDW QRSSTLSRPE
     YAPVADLVAP TDTTVIGQEA EHLMIGWKTP NAASYDTDTL RVIADILSNG KAGLFDVDLN
     QPMRVQSASA FSEGLHDYGM FVLYAVPTQG QSLEEAKGLV LAEMEKLRKG QFDEKLLRAV
     VNNLKLDYYK SLQSNSDRAD KFVKAFINEC KWEDEVRALD RISNMTKRQI VDYANRHLRD
     NYVVAYKKKG VDNSVKKIDK PAITPIPTNN DMQSDFLKDI VNAKVAPIEP RFVDFSKDLS
     KRDVDAKTVL LYKKNDSDGL FNLEFDIPVG RENDSRLHMA SALLDYAGTA KMSANDIKKA
     FYDLACNFNV SVRPNHTRLS LSGLNENMPA ALKLFTNLLE HATISKADYD KVVGLVLKSR
     QDSKQSQGGT YMALISYGVY GKTSPYLNSM TEEQLKASDG NELLLALRNA RHLNPMTIMY
     YGPTDEKTLL SLVKKDYPRR HVKATQPLNT VRYTAQPTPK NEVLLAHYDA KNIYMVQYNN
     ANRVWNMDNA PLVSMFNEYF SGGMNAIVFQ ELREARGLAY SASARYNAPY RLGDKEYFNT
     FIITQSDKMM DCIGEFNNLL NQIPQNQAGF ELAKQSLLKS LATNRHTRFN TLNYYMTMRE
     LGLNYDIDQK IYDKIPSITL DDIVNFAKER IANKPYKYLI VGDEKNLDTK SLEKIAPIRR
     VSEKEIFGF
//