ID A0A095YF96_9ACTO Unreviewed; 475 AA.
AC A0A095YF96;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Amino acid permease {ECO:0000313|EMBL:KGF05222.1};
GN ORFNames=HMPREF1627_01740 {ECO:0000313|EMBL:KGF05222.1};
OS Actinomyces sp. S6-Spd3.
OC Bacteria; Actinomycetota; Actinomycetes; Actinomycetales; Actinomycetaceae;
OC Actinomyces.
OX NCBI_TaxID=1284680 {ECO:0000313|EMBL:KGF05222.1, ECO:0000313|Proteomes:UP000029604};
RN [1] {ECO:0000313|EMBL:KGF05222.1, ECO:0000313|Proteomes:UP000029604}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=S6-Spd3 {ECO:0000313|EMBL:KGF05222.1,
RC ECO:0000313|Proteomes:UP000029604};
RA McCorrison J., Sanka R., Torralba M., Gillis M., Haft D.H., Methe B.,
RA Sutton G., Nelson K.E.;
RL Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the amino acid-polyamine-organocation (APC)
CC superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family.
CC {ECO:0000256|ARBA:ARBA00008583}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KGF05222.1}.
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DR EMBL; JRMV01000196; KGF05222.1; -; Genomic_DNA.
DR RefSeq; WP_034500480.1; NZ_JRMV01000196.1.
DR AlphaFoldDB; A0A095YF96; -.
DR PATRIC; fig|1284680.3.peg.175; -.
DR eggNOG; COG1113; Bacteria.
DR Proteomes; UP000029604; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
DR Gene3D; 1.20.1740.10; Amino acid/polyamine transporter I; 1.
DR InterPro; IPR004841; AA-permease/SLC12A_dom.
DR PANTHER; PTHR43495:SF2; D-SERINE_D-ALANINE_GLYCINE TRANSPORTER; 1.
DR PANTHER; PTHR43495; GABA PERMEASE; 1.
DR Pfam; PF00324; AA_permease; 1.
DR PIRSF; PIRSF006060; AA_transporter; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000029604};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 27..43
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 49..70
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 108..130
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 136..157
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 169..187
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 207..231
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 252..271
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 283..304
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 347..365
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 371..397
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 409..434
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 440..459
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 27..436
FT /note="Amino acid permease/ SLC12A"
FT /evidence="ECO:0000259|Pfam:PF00324"
SQ SEQUENCE 475 AA; 51300 MW; A5FFC0D1F5B14FE8 CRC64;
MSTSGHAEEN SGEASGRQLQ RNLTNRHIQL IAIGGAIGTG LFMGSGKTIA TAGPSILLVY
LIIGSALFLF MRAMGEILLS DRQYGTFADI IRHFLGPSMG FVMGWTYWLC WVVTGIADVV
AITGYVHFWW PDLPSWIPVV ATALLLFALN AMTVKAFGET EFWFAMIKIV AIIALIVVGV
IMVAIGMQDS NGTTAAVSNL WSHGGLFPTG FTGFLGGFQI AIFAFVGIEL VGTTVAETAD
PDTTLPKAIN SIPVRVVLFY ICSLAVIMMV TPWDQIDKTQ SPFVTMFSLT GLGMAASLVN
LVVLTSAASS ANSGIYSTSR MLFSLSLQGD AAPFFSRLSK RHVPQNALFL SCVFLLSAAI
LLVFGDSILS VFTVVTAMSA TLFMVVWVLV VIAYLFYVRK YPDKHQDSAF KLPGGVFSAW
LFIIFIALMV VVLALESESL KGLLMSAAWM VIITVVGVVR RHRALDRRGR APISA
//
