ID A0A095YFT5_9MICC Unreviewed; 639 AA.
AC A0A095YFT5;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE SubName: Full=Propionyl-CoA synthetase {ECO:0000313|EMBL:KGF20991.1};
DE EC=6.2.1.17 {ECO:0000313|EMBL:KGF20991.1};
GN Name=prpE {ECO:0000313|EMBL:KGF20991.1};
GN ORFNames=HMPREF2128_02955 {ECO:0000313|EMBL:KGF20991.1};
OS Pseudoglutamicibacter albus DNF00011.
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Micrococcaceae;
OC Pseudoglutamicibacter.
OX NCBI_TaxID=1401063 {ECO:0000313|EMBL:KGF20991.1, ECO:0000313|Proteomes:UP000053528};
RN [1] {ECO:0000313|EMBL:KGF20991.1, ECO:0000313|Proteomes:UP000053528}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DNF00011 {ECO:0000313|EMBL:KGF20991.1,
RC ECO:0000313|Proteomes:UP000053528};
RA McCorrison J., Sanka R., Torralba M., Gillis M., Haft D.H., Methe B.,
RA Sutton G., Nelson K.E.;
RL Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the ATP-dependent AMP-binding enzyme family.
CC {ECO:0000256|ARBA:ARBA00006432}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KGF20991.1}.
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DR EMBL; JRNH01000009; KGF20991.1; -; Genomic_DNA.
DR RefSeq; WP_035754883.1; NZ_JRNH01000009.1.
DR AlphaFoldDB; A0A095YFT5; -.
DR Proteomes; UP000053528; Unassembled WGS sequence.
DR GO; GO:0050218; F:propionate-CoA ligase activity; IEA:UniProtKB-EC.
DR CDD; cd05967; PrpE; 1.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR InterPro; IPR032387; ACAS_N.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR PANTHER; PTHR43347; ACYL-COA SYNTHETASE; 1.
DR PANTHER; PTHR43347:SF3; ACYL-COA SYNTHETASE SHORT-CHAIN FAMILY MEMBER 3, MITOCHONDRIAL; 1.
DR Pfam; PF16177; ACAS_N; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF13193; AMP-binding_C; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR PROSITE; PS00455; AMP_BINDING; 1.
PE 3: Inferred from homology;
KW Ligase {ECO:0000313|EMBL:KGF20991.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000053528}.
FT DOMAIN 6..60
FT /note="Acetyl-coenzyme A synthetase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF16177"
FT DOMAIN 67..459
FT /note="AMP-dependent synthetase/ligase"
FT /evidence="ECO:0000259|Pfam:PF00501"
FT DOMAIN 523..601
FT /note="AMP-binding enzyme C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13193"
SQ SEQUENCE 639 AA; 69624 MW; C6923FBC2A601B02 CRC64;
MTGENYREVY ERSINDPEGF WLEAASGIDW VSPPNKALDD SNPPFYKWFP DAELNTCYNA
VDRHVENGRG DQAAIIYDSA VLGKQETITY QELLERVSVF AGALRDQGVG KGDRVMIYMP
MVPEALIAML ATARLGAVHI GVFGGFAARE LASRIDDGTP KVVVTTSGGI EPSRRIEYIP
IIEEGMSIAE HKPTSVIVYE RDGFHTTVAE ARERAAESRG AAWISWDDAV AAAQPADPVT
VKATDPLYIL YTSGTTGKPK GVVRDNGGYA VAGVWSMKNV YNINPGDVSW TASDVGWVVG
HTYIVYAPLL AGATTIVYEG KPVGTPDAGA FWRVVSEHKA KILFTAPTAL RAIRKMDPDG
ELSKKYDLSS METLFAAGER LDPETYTWAS ELLNVPVIDN WWQTETGWPI CANLRGLDPM
PVKAGSPTVP VPGYNVQVLD PIGEPMPAGQ EGNLVIKLPM PPGTLQTLWG NDERFRSAYL
DAFPGFYATG DSGMVDEDGY VFVMGRTDDV INVSGHRLST GQMEQVVAEH PAVAECAVIG
VADPLKGQRP SGYVILKHGV EIDEQQLRDE VVALVRKEIG PVADFKHVAV VEALPKTRSG
KILRKTMRQM ADGEDYVVPS TIEDDSILEA LHEVLTRKG
//
