ID A0A095Z8L8_9CORY Unreviewed; 394 AA.
AC A0A095Z8L8;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 24-JAN-2024, entry version 27.
DE SubName: Full=Thiamine pyrophosphokinase {ECO:0000313|EMBL:KGF15107.1};
GN ORFNames=HMPREF1650_12085 {ECO:0000313|EMBL:KGF15107.1};
OS Corynebacterium freneyi DNF00450.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales;
OC Corynebacteriaceae; Corynebacterium.
OX NCBI_TaxID=1287475 {ECO:0000313|EMBL:KGF15107.1, ECO:0000313|Proteomes:UP000029548};
RN [1] {ECO:0000313|EMBL:KGF15107.1, ECO:0000313|Proteomes:UP000029548}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DNF00450 {ECO:0000313|EMBL:KGF15107.1,
RC ECO:0000313|Proteomes:UP000029548};
RA McCorrison J., Sanka R., Torralba M., Gillis M., Haft D.H., Methe B.,
RA Sutton G., Nelson K.E.;
RL Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KGF15107.1}.
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DR EMBL; JRNE01000082; KGF15107.1; -; Genomic_DNA.
DR RefSeq; WP_035123650.1; NZ_JRNE01000082.1.
DR AlphaFoldDB; A0A095Z8L8; -.
DR eggNOG; COG4825; Bacteria.
DR Proteomes; UP000029548; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0004788; F:thiamine diphosphokinase activity; IEA:InterPro.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR GO; GO:0009229; P:thiamine diphosphate biosynthetic process; IEA:InterPro.
DR Gene3D; 3.40.50.10240; Thiamin pyrophosphokinase, catalytic domain; 1.
DR InterPro; IPR047795; Put_SteA-like.
DR InterPro; IPR022215; SteA-like_C.
DR InterPro; IPR036759; TPK_catalytic_sf.
DR NCBIfam; NF040608; division_SteA; 1.
DR Pfam; PF12555; SteA-like_C; 1.
DR SUPFAM; SSF63999; Thiamin pyrophosphokinase, catalytic domain; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:KGF15107.1};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000029548};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 348..369
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 335..386
FT /note="SteA-like C-terminal"
FT /evidence="ECO:0000259|Pfam:PF12555"
SQ SEQUENCE 394 AA; 41527 MW; 5AF17ACF4298D913 CRC64;
MSLFSKKTAD EPGITGTVRD CLRSDRALNK LADGDIIVID APDITRVLAQ RIIDSKAKAV
LNTGAFTTGA VPNFGPQMLL DADVVLVENV ELTESSKLRD GKPHRLYEGK LYLGDRRVAA
GDEVTMDKIS ADFDEARTGM ADRLEAFSGN FVEFAATEAP LYVDGLGIPE VETKLDGRKV
LIVSGGEGHE RTLKNLKGFI GEFDPVLIGV DAGADTLVAQ GYEPDLIIGD PAGIEADTLR
SGARVILPAD PDGHAHGLEH IQDLGIGAMT FPALSDSATD LALVLADHHG ASMIVTAGSS
LDQGDVYAGA DQQSLPSALL SRLKAGDKLV NGDVVADLYR VEGGGLRIMW ALLAIIVALA
VIIAIAGTAG DGSVSENLID TWNSIALWFQ GLFK
//
