ID A0A095ZNJ5_9FIRM Unreviewed; 514 AA.
AC A0A095ZNJ5;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 24-JAN-2024, entry version 38.
DE RecName: Full=Ribonuclease Y {ECO:0000256|HAMAP-Rule:MF_00335};
DE Short=RNase Y {ECO:0000256|HAMAP-Rule:MF_00335};
DE EC=3.1.-.- {ECO:0000256|HAMAP-Rule:MF_00335};
GN Name=rny {ECO:0000256|HAMAP-Rule:MF_00335};
GN ORFNames=HMPREF1635_00645 {ECO:0000313|EMBL:KGF10129.1};
OS Clostridiales bacterium S5-A14a.
OC Bacteria; Bacillota; Clostridia; Eubacteriales;
OC Eubacteriales Family XIII. Incertae Sedis.
OX NCBI_TaxID=1230734 {ECO:0000313|EMBL:KGF10129.1, ECO:0000313|Proteomes:UP000029601};
RN [1] {ECO:0000313|EMBL:KGF10129.1, ECO:0000313|Proteomes:UP000029601}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=S5-A14a {ECO:0000313|EMBL:KGF10129.1,
RC ECO:0000313|Proteomes:UP000029601};
RA McCorrison J., Sanka R., Torralba M., Gillis M., Haft D.H., Methe B.,
RA Sutton G., Nelson K.E.;
RL Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Endoribonuclease that initiates mRNA decay.
CC {ECO:0000256|HAMAP-Rule:MF_00335}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|HAMAP-Rule:MF_00335};
CC Single-pass membrane protein {ECO:0000256|HAMAP-Rule:MF_00335}.
CC -!- SIMILARITY: Belongs to the RNase Y family. {ECO:0000256|HAMAP-
CC Rule:MF_00335}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KGF10129.1}.
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DR EMBL; JRNA01000003; KGF10129.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A095ZNJ5; -.
DR STRING; 1230734.HMPREF1635_00645; -.
DR OrthoDB; 9803205at2; -.
DR Proteomes; UP000029601; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0004521; F:RNA endonuclease activity; IEA:UniProtKB-UniRule.
DR GO; GO:0006402; P:mRNA catabolic process; IEA:UniProtKB-UniRule.
DR CDD; cd00077; HDc; 1.
DR CDD; cd22431; KH-I_RNaseY; 1.
DR Gene3D; 1.10.3210.10; Hypothetical protein af1432; 1.
DR Gene3D; 3.30.1370.10; K Homology domain, type 1; 1.
DR HAMAP; MF_00335; RNase_Y; 1.
DR InterPro; IPR003607; HD/PDEase_dom.
DR InterPro; IPR006674; HD_domain.
DR InterPro; IPR006675; HDIG_dom.
DR InterPro; IPR004087; KH_dom.
DR InterPro; IPR004088; KH_dom_type_1.
DR InterPro; IPR036612; KH_dom_type_1_sf.
DR InterPro; IPR017705; Ribonuclease_Y.
DR InterPro; IPR022711; RNase_Y_N.
DR NCBIfam; TIGR00277; HDIG; 1.
DR NCBIfam; TIGR03319; RNase_Y; 1.
DR PANTHER; PTHR12826; RIBONUCLEASE Y; 1.
DR PANTHER; PTHR12826:SF15; RIBONUCLEASE Y; 1.
DR Pfam; PF01966; HD; 1.
DR Pfam; PF00013; KH_1; 1.
DR Pfam; PF12072; RNase_Y_N; 1.
DR SMART; SM00471; HDc; 1.
DR SMART; SM00322; KH; 1.
DR SUPFAM; SSF54791; Eukaryotic type KH-domain (KH-domain type I); 1.
DR SUPFAM; SSF109604; HD-domain/PDEase-like; 1.
DR PROSITE; PS51831; HD; 1.
DR PROSITE; PS50084; KH_TYPE_1; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|HAMAP-Rule:MF_00335};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Endonuclease {ECO:0000256|ARBA:ARBA00022759, ECO:0000256|HAMAP-
KW Rule:MF_00335};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|HAMAP-Rule:MF_00335};
KW Membrane {ECO:0000256|HAMAP-Rule:MF_00335};
KW Nuclease {ECO:0000256|ARBA:ARBA00022722, ECO:0000256|HAMAP-Rule:MF_00335};
KW Reference proteome {ECO:0000313|Proteomes:UP000029601};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|HAMAP-
KW Rule:MF_00335}; Transmembrane {ECO:0000256|HAMAP-Rule:MF_00335};
KW Transmembrane helix {ECO:0000256|HAMAP-Rule:MF_00335}.
FT TRANSMEM 6..25
FT /note="Helical"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_00335"
FT DOMAIN 330..423
FT /note="HD"
FT /evidence="ECO:0000259|PROSITE:PS51831"
FT COILED 38..126
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 514 AA; 57754 MW; D3618E6C5841D9D0 CRC64;
MSPVFIVILV GLIALILGLL IGYIYRKNVG ERAIGSAEQK AKNLILDAEK KSESIKKEIV
LEAKEDASRI RSSLDREIRD RRNELSRSER RLLQKEESLD RKIENIEKKE ANITKKQETL
EKKNKEVDGF IEKQIQELEK ISGYTREEAK EILLSELEKD VRHDAALMIR NIESEAKEEA
DKKAKYIITG AIQRCAADHV AESTVSVVSL PNDDMKGRII GREGRNIIAL ENLTGVDLII
DDTPEAVIIS GFDPVRREIA RVALEKLILD GRIHPSKIEE MVEKATKEVN QIMKEEGEEA
TFEVGIHNLH PELVRLLGRL KYRTSYGQNV LKHSIEVSHL AGLMAGELGL DVKLAKRAGL
LHDIGKALDH EYEGTHVDIG IDILKKYKEN QAVINGMAAH HGDYEPQSME AVLIAAADAL
SAARPGARRE TLEVYIKRLQ QLEDIAATTH GVEKAFAIQA GREIRIIAKP EQVRDDEVAL
LAREISKKIE SELEYPGQIK VNVLRETRAI EYAK
//
