ID A0A096AK39_9FIRM Unreviewed; 343 AA.
AC A0A096AK39;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 24-JAN-2024, entry version 27.
DE RecName: Full=Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase {ECO:0000256|ARBA:ARBA00015486};
DE EC=2.4.2.21 {ECO:0000256|ARBA:ARBA00011991};
DE AltName: Full=N(1)-alpha-phosphoribosyltransferase {ECO:0000256|ARBA:ARBA00030686};
GN ORFNames=HMPREF0872_06425 {ECO:0000313|EMBL:KGF46996.1};
OS Veillonella montpellierensis DNF00314.
OC Bacteria; Bacillota; Negativicutes; Veillonellales; Veillonellaceae;
OC Veillonella.
OX NCBI_TaxID=1401067 {ECO:0000313|EMBL:KGF46996.1, ECO:0000313|Proteomes:UP000029628};
RN [1] {ECO:0000313|EMBL:KGF46996.1, ECO:0000313|Proteomes:UP000029628}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DNF00314 {ECO:0000313|EMBL:KGF46996.1,
RC ECO:0000313|Proteomes:UP000029628};
RA McCorrison J., Sanka R., Torralba M., Gillis M., Haft D.H., Methe B.,
RA Sutton G., Nelson K.E.;
RL Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=5,6-dimethylbenzimidazole + nicotinate beta-D-ribonucleotide =
CC alpha-ribazole 5'-phosphate + H(+) + nicotinate;
CC Xref=Rhea:RHEA:11196, ChEBI:CHEBI:15378, ChEBI:CHEBI:15890,
CC ChEBI:CHEBI:32544, ChEBI:CHEBI:57502, ChEBI:CHEBI:57918; EC=2.4.2.21;
CC Evidence={ECO:0000256|ARBA:ARBA00001058};
CC -!- PATHWAY: Nucleoside biosynthesis; alpha-ribazole biosynthesis; alpha-
CC ribazole from 5,6-dimethylbenzimidazole: step 1/2.
CC {ECO:0000256|ARBA:ARBA00005049}.
CC -!- SIMILARITY: Belongs to the CobT family.
CC {ECO:0000256|ARBA:ARBA00007110}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KGF46996.1}.
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DR EMBL; JRNT01000022; KGF46996.1; -; Genomic_DNA.
DR RefSeq; WP_038152833.1; NZ_JRNT01000022.1.
DR AlphaFoldDB; A0A096AK39; -.
DR eggNOG; COG2038; Bacteria.
DR UniPathway; UPA00061; UER00516.
DR Proteomes; UP000029628; Unassembled WGS sequence.
DR GO; GO:0008939; F:nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-KW.
DR CDD; cd02439; DMB-PRT_CobT; 1.
DR Gene3D; 1.10.1610.10; -; 1.
DR Gene3D; 3.40.50.10210; -; 1.
DR InterPro; IPR003200; Nict_dMeBzImd_PRibTrfase.
DR InterPro; IPR023195; Nict_dMeBzImd_PRibTrfase_N.
DR InterPro; IPR036087; Nict_dMeBzImd_PRibTrfase_sf.
DR PANTHER; PTHR43463; NICOTINATE-NUCLEOTIDE--DIMETHYLBENZIMIDAZOLE PHOSPHORIBOSYLTRANSFERASE; 1.
DR PANTHER; PTHR43463:SF1; NICOTINATE-NUCLEOTIDE--DIMETHYLBENZIMIDAZOLE PHOSPHORIBOSYLTRANSFERASE; 1.
DR Pfam; PF02277; DBI_PRT; 1.
DR SUPFAM; SSF52733; Nicotinate mononucleotide:5,6-dimethylbenzimidazole phosphoribosyltransferase (CobT); 1.
PE 3: Inferred from homology;
KW Cobalamin biosynthesis {ECO:0000256|ARBA:ARBA00022573};
KW Glycosyltransferase {ECO:0000256|ARBA:ARBA00022676,
KW ECO:0000313|EMBL:KGF46996.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000029628};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:KGF46996.1}.
SQ SEQUENCE 343 AA; 36330 MW; AC107848D8F52528 CRC64;
MSTFKETCAA ITARNRDIET AIKEEWQQRD CVEAYGKLVP MVAQYGAATE QVSPMPPKRC
MIIASADHGI AKLGVSAYPI ETTVGMTQNY LIPKGAGANA LANYCEADME VIDMGVAADM
SWVPGLRSCK LGMGTRNFLE GPAMTKEQAI KGIEAGIQLV EEKHGEGYNV FLVGEMGIAN
TTSSALMTAK FAGLTADEAT GRGSNISDER LKLKQRVVHD TLVKYKDIPS TDGLGILAAV
GGFEFACIVG VILGAAAHKC MVIIDGFNTT ACAMVAHSLA PMSMDYVMAS HLSAEKAHKN
ALAKMGLAAY VDLGLCLGEA SGGSIQMGML DLAVHMYRTM KGV
//
