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Database: UniProt
Entry: A0A096CU74_9CLOT
LinkDB: A0A096CU74_9CLOT
Original site: A0A096CU74_9CLOT 
ID   A0A096CU74_9CLOT        Unreviewed;       444 AA.
AC   A0A096CU74;
DT   26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT   26-NOV-2014, sequence version 1.
DT   16-JAN-2019, entry version 34.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|HAMAP-Rule:MF_00377, ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS01081161};
GN   Name=dnaA {ECO:0000256|HAMAP-Rule:MF_00377};
GN   ORFNames=Y919_08290 {ECO:0000313|EMBL:KGG80074.1};
OS   Caloranaerobacter azorensis H53214.
OC   Bacteria; Firmicutes; Clostridia; Clostridiales; Clostridiaceae;
OC   Caloranaerobacter.
OX   NCBI_TaxID=1156417 {ECO:0000313|EMBL:KGG80074.1, ECO:0000313|Proteomes:UP000029622};
RN   [1] {ECO:0000313|EMBL:KGG80074.1, ECO:0000313|Proteomes:UP000029622}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=H53214 {ECO:0000313|EMBL:KGG80074.1,
RC   ECO:0000313|Proteomes:UP000029622};
RA   Jiang L.J., Shao Z.Z., Long M.N.;
RT   "Draft genome sequence of Caloranaerobacter sp. H53214.";
RL   Submitted (DEC-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00756121}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|SAAS:SAAS01082709}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00377, ECO:0000256|RuleBase:RU004227,
CC       ECO:0000256|SAAS:SAAS00555179}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:KGG80074.1}.
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DR   EMBL; AZTB01000041; KGG80074.1; -; Genomic_DNA.
DR   RefSeq; WP_035163915.1; NZ_AZTB01000041.1.
DR   EnsemblBacteria; KGG80074; KGG80074; Y919_08290.
DR   OrthoDB; 219876at2; -.
DR   Proteomes; UP000029622; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-UniRule.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-UniRule.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   Gene3D; 3.30.300.180; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR024633; DnaA_N_dom.
DR   InterPro; IPR038454; DnaA_N_sf.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF2; PTHR30050:SF2; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   Pfam; PF11638; DnaA_N; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00756129};
KW   Complete proteome {ECO:0000313|Proteomes:UP000029622};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|SAAS:SAAS01082702};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00756116};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS01082706};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00756117};
KW   Reference proteome {ECO:0000313|Proteomes:UP000029622}.
FT   DOMAIN      139    267       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      351    420       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
FT   NP_BIND     147    154       ATP. {ECO:0000256|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   444 AA;  50732 MW;  E1AA31B6EC022C53 CRC64;
     MNLNLDDIWN DTLKLIKTEL TEVSFNTWFK TIEPLTINDN QILLGVPNEF TKGILVARYL
     ILIKNAIKQI TNKDFDIKFI IPGEEITDIG QTIQNEINDN STSRAQLNPK YTFDTFVIGN
     SNRFAHAASL AVAEAPAKAY NPLFIYGGVG LGKTHLMHAI GHYILNQNPK AKVVYVSSEK
     FTNELINSIR DDRNVEFRNK YRNVDVLLID DIQFIAGKER TQEEFFHTFN ALHEANKQII
     ISSDRPPKEI PTLEDRLRSR FEWGLIADIQ PPDLETRIAI LRKKAKVENI HVPNDVMLYI
     ATKIQSNIRE LEGALIRIVA YSSLTNREVT VDLATEALKD IISNTKPREI NVKLIKEIVA
     QNFNVKVEDF DSKKRTRSIA YPRQIAMYLC RELTDLSLPK IGDEFGGRDH TTVIHAYDKI
     SSDIKNNSEL KLKIENIINE IKGK
//
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