ID A0A096LQY8_POEFO Unreviewed; 2367 AA.
AC A0A096LQY8;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 53.
DE RecName: Full=RNA helicase {ECO:0000256|ARBA:ARBA00012552};
DE EC=3.6.4.13 {ECO:0000256|ARBA:ARBA00012552};
OS Poecilia formosa (Amazon molly) (Limia formosa).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC Poecilia.
OX NCBI_TaxID=48698 {ECO:0000313|Ensembl:ENSPFOP00000021579.1, ECO:0000313|Proteomes:UP000028760};
RN [1] {ECO:0000313|Proteomes:UP000028760}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=female {ECO:0000313|Proteomes:UP000028760};
RA Schartl M., Warren W.;
RL Submitted (OCT-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSPFOP00000021579.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR EMBL; AYCK01025874; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR Ensembl; ENSPFOT00000031486.1; ENSPFOP00000021579.1; ENSPFOG00000001606.2.
DR GeneTree; ENSGT00940000166655; -.
DR OMA; DLYIREH; -.
DR Proteomes; UP000028760; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0004540; F:RNA nuclease activity; IEA:InterPro.
DR CDD; cd18808; SF1_C_Upf1; 2.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 4.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR041679; DNA2/NAM7-like_C.
DR InterPro; IPR041677; DNA2/NAM7_AAA_11.
DR InterPro; IPR012340; NA-bd_OB-fold.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR001900; RNase_II/R.
DR InterPro; IPR047187; SF1_C_Upf1.
DR PANTHER; PTHR43788; DNA2/NAM7 HELICASE FAMILY MEMBER; 1.
DR PANTHER; PTHR43788:SF9; HELICASE WITH ZINC FINGER DOMAIN 2; 1.
DR Pfam; PF13086; AAA_11; 3.
DR Pfam; PF13087; AAA_12; 2.
DR Pfam; PF00773; RNB; 1.
DR SMART; SM00382; AAA; 2.
DR SMART; SM00955; RNB; 1.
DR SUPFAM; SSF50249; Nucleic acid-binding proteins; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000028760}.
FT DOMAIN 350..539
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
FT DOMAIN 1039..1394
FT /note="Ribonuclease II/R"
FT /evidence="ECO:0000259|SMART:SM00955"
FT DOMAIN 1890..2086
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
SQ SEQUENCE 2367 AA; 270594 MW; 90E71FBB6209A495 CRC64;
FCVFLQRKLL HVALLKQEPG ASFSLTDNSS EPCIYSAGER FLSNNMTYAI TVSFTSTHPG
LYEQWLVLDF GIRPVLLKKL KVRVGQQSVD DTKEQVFNNG VILQSAERWN RGNRVIIPCS
YRTEKQEELM KAYKPPQLTL LYKPSCYSQA ALTAENYKTK MHEFLYNEER AEDQVVSRLN
VCGQITTITR LNDPKFGMEF ARQGELFCSV SIPHKLTMDS AEGLVLKRNV QSALIAPVDS
LHPKSKVYEA KVLNLRTNEN QIHLQLSKQC CSDLSLKDNQ SYQMEVQFQL DRLSFCTMHK
AVDLLPDTTR VLPDLKHCGV PVSDVTYENL NSKQQSALGF ITGNHDGGKF TAPLLIYGPF
GTGKTFTIAT AAIELCRHPQ NKILICTHTN SSADLYIREH FHPAISKNNK LRPIRIKAKS
EKALFATDEI TLKYCFLSED RKSFLPPNKD VLEDHNVVVT TTTMAGLFHD LKLAEGLFTH
ILIDEASQML ECEALLALSL AGPNTRVILA GDHMQMGPQL FSVDDHRRSD CTLLTRLFHY
YQGQKCDAAQ SSRIIFSQNY RSTKEIVEFV STHFYVGKGD VIEASGDVPA PPNDHALRFH
HVRGECVLDI VTMSWYNKQE SFKVTEVVED IVNNWPTNWG PKDLKSICVL SEGSQVRQIR
SILLRKGFSE VNVETLANVQ GKQFRAVILT AVQTRDSLKE SNPSGLPLFN DARVLNTAMT
RAQSQVTVVG DAAALCCFGK CSRFWQSFII HCFSNNSVEP KHYTEGFFEQ DVGETVRFQK
LEDIDEKTMS DSILQELRDE YEQMKTEYSS DEESLESEDF THQKFGKSFK VSSEQELIEL
CEKQPELFKK GKFVKESYNR GHVVTFHKPT WRIHVQGRSN MGRAFTGDEV VVQTARGGQP
ARVLGIVKEK ESAREFVCFL DNKFVKRVMM PVNKNAPKIT ILLLEQRRNF LPVWEEISGY
WTIIRSHHIR EVRDKAFVVQ VIGWKERCLY PLGKVTDVLP TSGPLNDRLW LLKEEFEVKD
TNLDTYEGLP NKDKDSEKRQ DETETITFTV DPLGAKDLDD AISIRDTGDH YELGVHIADV
ASYVSPGDEL DKHAEERGST HYPGGEPIHM FPGNLSTGQF SLLPHQDRRA VSLMLKVEKE
THKIFEDPKF QLSMIRSKRQ FTYEEAEEII TQRYRHPPAF STEEDGVTVA YHFAKVQRKL
RLGREWAYYQ GDDDSSPGKR KAHQMIEEIS LLFNNYTAKY LCESKARYHT PLRCQSSPDP
EKLETFKEKC GALIQLSFSV NHDEMTVPNS EPSTERFPIL ETVWNDIQSA LRENDTDKLV
DLVGADDFYP LLQPVIYELQ RCRSKAYLIR SKSSEAAEVG HHSLKLNPYT QASSPIRRYM
DLILQRLLHS FICNDALQYT RTKITDLCHQ FDPNSKKVRQ FEQKAQQVFY AVSTQQQSAP
KLAFVVSADP DEESFKVLFP FNRNIFRLPL SVMFSELQLE DQPTYDSDKK YIMLKWKRRI
YAADERVIHQ ELIKMSGRGP CIEIPLTVWT AVIEAVQTEN LDQAKSLLMD TRPYTRPLEP
ETEDSPSVFQ HYSDIDLHLQ PGGTMQVQMT SEGSRGCHMP VIQLVHIKPM FEICVQHVHN
PISCYTQSAQ EPAKPFYKDT KQYMEIWKPI CEMESAVNAV EESDSIIIEN LEVKFTQWLE
DTMTGKFFLH QKWITDWVIE CDLGKCLLCI RKRGLKLPLP REHSAPVDPK EFTWVAHGFT
TKVDSRKTGS EVDFHVSHLP MKRVPECVFK RNTLFTAEII PKLLPDIRKE AAVLNLETAC
DLVKRIALGH KIPKKDSYWR GRVDSGQVSN LWPGRWTEQS IFNTDVICIV HQTPIMPSSV
LKHQIARKKL PAKLPELNDS QLQAVAAALN NRFTLIQGPP GTGKTVVGVN IVYWFFEMNS
KNPRISEDRR DKDKKEVILY CGPSNKSVDV VAEYLMRFKN SLRILRVYGQ QVENVEYPYP
NSDLQFSQRS LRQDKSNPEL RSITLHHRIR EPQNHFSEKI KQFDERIRLK EVLTLEEVKE
YRRILKEART LELKRHDIIL CTCTQSSTPI LSSTVSARQI LIDESAMATE PQTLIPLVSF
NNIPKVVLIG DHKQLQPIVK NQSVKKLGMT TSLFERYYTR LHKNTAVMLD TQYRMHQGIC
EFPSKQFYES KLKTGEEQPS SLLRVNGKTM PIVFGHVEGK TIRLVVKTAK GNNKSKVNHS
EKEKVTQIAE MLVKAGVDER SIVVLSPYNA QVAEIREELT KMKLGGITVT TITKSQGSEW
RYVILSTVCS VPSREIEKEP DGAWMSKHVG FVGDPHQINV AITRAKEGLC IIGKGNQKLL
QLSPSWRHLL DYYCLHSALT DAEKISV
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