ID A0A096LQZ0_POEFO Unreviewed; 199 AA.
AC A0A096LQZ0;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 24-JAN-2024, entry version 29.
DE RecName: Full=TNFR-Cys domain-containing protein {ECO:0000259|PROSITE:PS50050};
OS Poecilia formosa (Amazon molly) (Limia formosa).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC Poecilia.
OX NCBI_TaxID=48698 {ECO:0000313|Ensembl:ENSPFOP00000021581.1, ECO:0000313|Proteomes:UP000028760};
RN [1] {ECO:0000313|Proteomes:UP000028760}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=female {ECO:0000313|Proteomes:UP000028760};
RA Schartl M., Warren W.;
RL Submitted (OCT-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSPFOP00000021581.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00206}.
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DR EMBL; AYCK01013143; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; A0A096LQZ0; -.
DR Ensembl; ENSPFOT00000025578.1; ENSPFOP00000021581.1; ENSPFOG00000023779.1.
DR GeneTree; ENSGT00950000183126; -.
DR Proteomes; UP000028760; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0004888; F:transmembrane signaling receptor activity; IEA:InterPro.
DR GO; GO:0006915; P:apoptotic process; IEA:InterPro.
DR GO; GO:0006955; P:immune response; IEA:InterPro.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd00185; TNFRSF; 1.
DR CDD; cd13405; TNFRSF14_teleost; 1.
DR Gene3D; 2.10.50.10; Tumor Necrosis Factor Receptor, subunit A, domain 2; 3.
DR InterPro; IPR008063; Fas_rcpt.
DR InterPro; IPR001368; TNFR/NGFR_Cys_rich_reg.
DR PANTHER; PTHR46838; TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 14; 1.
DR PANTHER; PTHR46838:SF1; TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 14; 1.
DR Pfam; PF00020; TNFR_c6; 1.
DR PRINTS; PR01680; TNFACTORR6.
DR SMART; SM00208; TNFR; 3.
DR SUPFAM; SSF57586; TNF receptor-like; 2.
DR PROSITE; PS00652; TNFR_NGFR_1; 1.
DR PROSITE; PS50050; TNFR_NGFR_2; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|PROSITE-ProRule:PRU00206};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000028760};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 161..181
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REPEAT 25..67
FT /note="TNFR-Cys"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00206"
FT DOMAIN 25..67
FT /note="TNFR-Cys"
FT /evidence="ECO:0000259|PROSITE:PS50050"
FT DISULFID 26..41
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00206"
SQ SEQUENCE 199 AA; 21524 MW; 1E664B810A2C15BD CRC64;
CCPMCRPGTR VKTDCIEFKS ISCQKCPETT YMDLPNGLKR CYPCSTCDSG AGLKEKLGCE
RTANTVCEPI EGFFCTDLKS GGCAAAQKHR SCEPGQFISK MGTASTDTEC SECSSGSFSD
GTMLSCQLHT QCEKENLQLI KAGTASTDAE CGEKSSNTTG IVIGVLVFFL VAATIGGVFL
WKYHKNTKPS EMNKYKLKY
//
