ID A0A096LWV1_POEFO Unreviewed; 1227 AA.
AC A0A096LWV1;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 24-JAN-2024, entry version 40.
DE RecName: Full=Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 3 {ECO:0000256|ARBA:ARBA00016171};
DE AltName: Full=Membrane-associated guanylate kinase inverted 3 {ECO:0000256|ARBA:ARBA00033438};
OS Poecilia formosa (Amazon molly) (Limia formosa).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC Poecilia.
OX NCBI_TaxID=48698 {ECO:0000313|Ensembl:ENSPFOP00000023642.1, ECO:0000313|Proteomes:UP000028760};
RN [1] {ECO:0000313|Proteomes:UP000028760}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=female {ECO:0000313|Proteomes:UP000028760};
RA Schartl M., Warren W.;
RL Submitted (OCT-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSPFOP00000023642.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the MAGUK family.
CC {ECO:0000256|ARBA:ARBA00007014}.
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DR EMBL; AYCK01005417; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AYCK01005418; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; A0A096LWV1; -.
DR STRING; 48698.ENSPFOP00000023642; -.
DR Ensembl; ENSPFOT00000028360.1; ENSPFOP00000023642.1; ENSPFOG00000013628.2.
DR eggNOG; KOG3209; Eukaryota.
DR GeneTree; ENSGT00940000156496; -.
DR Proteomes; UP000028760; Unassembled WGS sequence.
DR CDD; cd00992; PDZ_signaling; 5.
DR CDD; cd00201; WW; 2.
DR Gene3D; 2.20.70.10; -; 2.
DR Gene3D; 2.30.42.10; -; 5.
DR InterPro; IPR001478; PDZ.
DR InterPro; IPR036034; PDZ_sf.
DR InterPro; IPR001202; WW_dom.
DR InterPro; IPR036020; WW_dom_sf.
DR PANTHER; PTHR10316; MEMBRANE ASSOCIATED GUANYLATE KINASE-RELATED; 1.
DR PANTHER; PTHR10316:SF10; MEMBRANE-ASSOCIATED GUANYLATE KINASE, WW AND PDZ DOMAIN-CONTAINING PROTEIN 3; 1.
DR Pfam; PF00595; PDZ; 4.
DR Pfam; PF00397; WW; 2.
DR SMART; SM00228; PDZ; 5.
DR SMART; SM00456; WW; 2.
DR SUPFAM; SSF50156; PDZ domain-like; 5.
DR SUPFAM; SSF51045; WW domain; 2.
DR PROSITE; PS50106; PDZ; 5.
DR PROSITE; PS01159; WW_DOMAIN_1; 2.
DR PROSITE; PS50020; WW_DOMAIN_2; 2.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000028760}.
FT DOMAIN 60..93
FT /note="WW"
FT /evidence="ECO:0000259|PROSITE:PS50020"
FT DOMAIN 106..139
FT /note="WW"
FT /evidence="ECO:0000259|PROSITE:PS50020"
FT DOMAIN 185..254
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 359..422
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 544..627
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 679..766
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 827..909
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT REGION 1..36
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 143..176
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 274..349
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 440..477
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 630..653
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 765..802
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 928..1227
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 18..35
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 275..304
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 451..465
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 639..653
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 768..797
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 928..955
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 980..994
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1032..1074
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1088..1167
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1178..1202
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1210..1227
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1227 AA; 133602 MW; 4D5CD6E75B37EEC9 CRC64;
MDRMDSTAPE EEEEEERPPM VNGVGEHKDK ADWRKTVPSY NQSAGAMDMR VWNTLDESQE
PLPKNWEMAY TETGMVYFID HNTKTTTWLD PRLAKKAKPP EKCIEGELPY GWEKIEDPQF
GTYYVDHINQ KTQFENPVME AKRKLSDDTP TAVQPPAAAP SEEEPARGLR GFTRDPSQLQ
GSILQTSLKK SPLGFGFTII GGDRPDEFLQ VKNVLPDGPA AHDNKIAPGD VIVDINGACV
LGKTHADVVQ MFQSIPINQY VDLVLCRGYP LPEDSNSSED ASASLNASKE ASPTPSSSNP
QEPHFTVPDG GHLSRQAAAV PALSNGGRHH HHPQQHQHLP LTHNQEAPDP TLLQPELVSV
PLVKGPGGFG FAIADCPLGQ KVKMILDAQW CRGLLKGDVI KEINRQNVQT LSHAQVVDIL
KDLPVGSEVN VLVLRGGQTS PVKSLKPERA SMPHATSQHS LQHPPHAVSH QLPHPASQPV
VQLQQRQEMA NSTETLSQPE VLSNALPVST NTLRSSSPKP DPSELYLKSK AMLDSKPPNT
KDLDVFIKRN QESGFGFRVL GGEGPDQPVY IGAIVPLGAA EKDGRLRAGD ELLCIDGVPV
KGKSHKQVLE LMTNAARNGQ VMLTVRRKLT HTEGGEEEES GQQPQQVASA LVNSSPKVPR
VEAPNAVQPA QLPRPESFDV TLQRKDNEGF GFVILTSKNK PPPGVIPHKI GRIIEGSPTD
RIGRMKVGDR ISAVNGQSIM ELSHNDIVQL IKDAGNTVTL TVVPEEDSAP PSGTNSVKHS
PSIQHRAMGQ QPSSHLDRAA ESEMRNSLQP NEMGAIATSG PKQGCFVVEL ERSQRGFGFS
LRGGKEYNMG LYILRLAEEG PALKDGRIHV GDQIVEINGE ATQGITHTRA IELIQAGGNK
VHLLLRPGQG LVPDHSTKDK VAIPTTSFPR LSASDDQSSP ASPSTGWSPS SSKVFAPDEP
SAGDYRVPGF PGAGQEHGRQ ANRSRGQQIP THNHRRSTSP RKTGQSDYKS GSPRKMAEGQ
MDNVEHSQNP QKTMEDVSKE RKTSGQKDQR SSSPRKGSKR ELDPVLHSKN PEDPQSPRRP
AGQQPAGEVR DWRHKGEDAT HPQERGAAES GDKSWGADDH HKKGKRAQKE AAAQKSHRER
AGSDADPATT GQRGRRERAE KEYPEAKYQG PAEQANRRDP RGSSSSIQDP NCNGTSTSKK
APITPGPWKV PSSTKIQSHV DSTYADI
//
