ID A0A096LXL5_POEFO Unreviewed; 496 AA.
AC A0A096LXL5;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 24-JAN-2024, entry version 38.
DE SubName: Full=Rap guanine nucleotide exchange factor (GEF)-like 1 {ECO:0000313|Ensembl:ENSPFOP00000023906.1};
GN Name=RAPGEFL1 {ECO:0000313|Ensembl:ENSPFOP00000023906.1};
OS Poecilia formosa (Amazon molly) (Limia formosa).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC Poecilia.
OX NCBI_TaxID=48698 {ECO:0000313|Ensembl:ENSPFOP00000023906.1, ECO:0000313|Proteomes:UP000028760};
RN [1] {ECO:0000313|Proteomes:UP000028760}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=female {ECO:0000313|Proteomes:UP000028760};
RA Schartl M., Warren W.;
RL Submitted (OCT-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSPFOP00000023906.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR EMBL; AYCK01010463; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; A0A096LXL5; -.
DR STRING; 48698.ENSPFOP00000023906; -.
DR Ensembl; ENSPFOT00000032001.1; ENSPFOP00000023906.1; ENSPFOG00000023586.1.
DR eggNOG; KOG2378; Eukaryota.
DR GeneTree; ENSGT00940000160144; -.
DR OMA; LQPNEDC; -.
DR Proteomes; UP000028760; Unassembled WGS sequence.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.
DR GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
DR CDD; cd00155; RasGEF; 1.
DR Gene3D; 1.10.840.10; Ras guanine-nucleotide exchange factors catalytic domain; 1.
DR Gene3D; 1.20.870.10; Son of sevenless (SoS) protein Chain: S domain 1; 1.
DR InterPro; IPR008937; Ras-like_GEF.
DR InterPro; IPR019804; Ras_G-nucl-exch_fac_CS.
DR InterPro; IPR023578; Ras_GEF_dom_sf.
DR InterPro; IPR001895; RASGEF_cat_dom.
DR InterPro; IPR036964; RASGEF_cat_dom_sf.
DR InterPro; IPR029071; Ubiquitin-like_domsf.
DR PANTHER; PTHR23113; GUANINE NUCLEOTIDE EXCHANGE FACTOR; 1.
DR PANTHER; PTHR23113:SF230; RAP GUANINE NUCLEOTIDE EXCHANGE FACTOR-LIKE 1; 1.
DR Pfam; PF00617; RasGEF; 1.
DR SMART; SM00147; RasGEF; 1.
DR SUPFAM; SSF48366; Ras GEF; 1.
DR SUPFAM; SSF54236; Ubiquitin-like; 1.
DR PROSITE; PS00720; RASGEF; 1.
DR PROSITE; PS50009; RASGEF_CAT; 1.
PE 4: Predicted;
KW Guanine-nucleotide releasing factor {ECO:0000256|ARBA:ARBA00022658,
KW ECO:0000256|PROSITE-ProRule:PRU00168};
KW Reference proteome {ECO:0000313|Proteomes:UP000028760}.
FT DOMAIN 258..494
FT /note="Ras-GEF"
FT /evidence="ECO:0000259|PROSITE:PS50009"
SQ SEQUENCE 496 AA; 57418 MW; BC87FB9FE4F95962 CRC64;
AETLLDDFML THPIFLTADR LQFSLEAQVG GGERRDGEAE ASMSAAERKQ AVLNMAFRYL
DTYRELLQEE GERSNSFPKE LYMCAVQELT RYPELVEDVL KLQRWSEILH CPSDEEKESR
KKQVRPLFRH FRRIDACLQP REAFRGSDEI FCRVYTPDHS YVTIRSRLSC RVGEILALVK
EKLQYSEDQP VLPGNLILVA VTSAGEKAVF RPSDEAVFTT LGVNTHLFAC EPSELDSLLP
LPEEIHWTPG DSKLHDMSAE EVANQLVVFD WELFSCVHEV EFICYVFHGE QSRWRPLNLE
LVLQRCSEVQ HWVATEILQC QSLPKRIQLL RKFIKIAALC KQQQDLLSFL AVVLGLDNPA
VSRLRLTWEG LPGKFRKQFQ QFESIADPSR NHKSYRDLIT SLRPPLIPFT PLLLKDLTFL
HESCKTFHGE FVNFEKMHKV AEMVRTIRRY RSSQLAIDTE TSPSHLQTKA YVRQLQVIDN
QNLLFDMSCK LEPKDT
//
