ID A0A096LY15_POEFO Unreviewed; 612 AA.
AC A0A096LY15;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 44.
DE SubName: Full=Cytoplasmic dynein 1 intermediate chain 2-like {ECO:0000313|Ensembl:ENSPFOP00000024056.1};
GN Name=DYNC1I2 {ECO:0000313|Ensembl:ENSPFOP00000024056.1};
OS Poecilia formosa (Amazon molly) (Limia formosa).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC Poecilia.
OX NCBI_TaxID=48698 {ECO:0000313|Ensembl:ENSPFOP00000024056.1, ECO:0000313|Proteomes:UP000028760};
RN [1] {ECO:0000313|Proteomes:UP000028760}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=female {ECO:0000313|Proteomes:UP000028760};
RA Schartl M., Warren W.;
RL Submitted (OCT-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSPFOP00000024056.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the dynein intermediate chain family.
CC {ECO:0000256|ARBA:ARBA00011059}.
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DR EMBL; AYCK01010605; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; A0A096LY15; -.
DR Ensembl; ENSPFOT00000025123.1; ENSPFOP00000024056.1; ENSPFOG00000009232.2.
DR GeneTree; ENSGT00940000155442; -.
DR Proteomes; UP000028760; Unassembled WGS sequence.
DR GO; GO:0005868; C:cytoplasmic dynein complex; IEA:InterPro.
DR GO; GO:0007018; P:microtubule-based movement; IEA:InterPro.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 2.
DR InterPro; IPR025956; DYNC1I1/DYNC1I2.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR12442:SF44; CYTOPLASMIC DYNEIN 1 INTERMEDIATE CHAIN 2 ISOFORM X1; 1.
DR PANTHER; PTHR12442; DYNEIN INTERMEDIATE CHAIN; 1.
DR Pfam; PF11540; Dynein_IC2; 1.
DR Pfam; PF00400; WD40; 2.
DR SMART; SM00320; WD40; 7.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS50082; WD_REPEATS_2; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000028760};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW ProRule:PRU00221}.
FT REPEAT 446..493
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REGION 1..43
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 83..113
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 131..187
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..22
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 86..100
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 145..159
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 160..187
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 612 AA; 67598 MW; 22C203F23D4A5DFE CRC64;
MSDKSELKAE LERKKQRIAQ IGESKRGAEA GPAGGEDSDL ERKRREAEAL LQSVGITPDV
PHAQPLRVVT EDTCLFHYLV PAPMSPSNKS VGSDAGSQDS GDGNAGPRRG TVRLGMSKLI
QVDFVPKEMV SYSKETQTPT EASAHTDEEE DEEISAPPLT EDAQDEKNEQ SEQQEEDAPK
ELTEEEKLQV LHSDEFLSFF ERGSRIVERA LAEQVDVCFD YSGRDLEDKE GDLQAGAKLV
QNRQFADERW TKNRVVTCLD WSPQYPELLV ASYNNNEDAP YEPDGVALVW NMKYKKATPE
YIFHCQSEVM SAGFAKFHPN LVVGGTYSGQ IVLWDNRSNK RTPVQRTPLS ASAHTHPVYC
VNVVGTQNAH NLISISTDGK MCSWSLDMLS QPQDSLELVF KQSKAVAVTS MAFPLGDVNN
FVVGSEDGSV YTACRHGSKA GITEVFEGHH GPVTGLSCHS AAGPVDFSHL FISSSFDWTV
KLWSTKSTRP LYSFEDSSDY VYDSMWSPAH PALFACVDLS GRLDLWNLNN DTEVPTASVC
VEGSSALNRV RWSHSGKEIA TGDSDGQVQV YDVGEQICVP KADEWTRFVR TLAEINENRD
EAEELANPEL GP
//
