GenomeNet

Database: UniProt
Entry: A0A096LY31_POEFO
LinkDB: A0A096LY31_POEFO
Original site: A0A096LY31_POEFO 
ID   A0A096LY31_POEFO        Unreviewed;      3123 AA.
AC   A0A096LY31;
DT   26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT   26-NOV-2014, sequence version 1.
DT   05-JUN-2019, entry version 34.
DE   SubName: Full=Laminin subunit alpha 2 {ECO:0000313|Ensembl:ENSPFOP00000024072};
GN   Name=LAMA2 {ECO:0000313|Ensembl:ENSPFOP00000024072};
OS   Poecilia formosa (Amazon molly) (Limia formosa).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae;
OC   Poeciliinae; Poecilia.
OX   NCBI_TaxID=48698 {ECO:0000313|Ensembl:ENSPFOP00000024072, ECO:0000313|Proteomes:UP000028760};
RN   [1] {ECO:0000313|Ensembl:ENSPFOP00000024072, ECO:0000313|Proteomes:UP000028760}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=female {ECO:0000313|Ensembl:ENSPFOP00000024072};
RA   Schartl M., Warren W.;
RL   Submitted (OCT-2013) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSPFOP00000024072}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (OCT-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: Lacks conserved residue(s) required for the propagation
CC       of feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00122}.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   -----------------------------------------------------------------------
DR   EMBL; AYCK01000230; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   Ensembl; ENSPFOT00000029085; ENSPFOP00000024072; ENSPFOG00000017974.
DR   GeneTree; ENSGT00940000155362; -.
DR   Proteomes; UP000028760; Unassembled WGS sequence.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005102; F:signaling receptor binding; IEA:InterPro.
DR   GO; GO:0007155; P:cell adhesion; IEA:InterPro.
DR   GO; GO:0030155; P:regulation of cell adhesion; IEA:InterPro.
DR   GO; GO:0030334; P:regulation of cell migration; IEA:InterPro.
DR   GO; GO:0045995; P:regulation of embryonic development; IEA:InterPro.
DR   Gene3D; 2.60.120.1490; -; 1.
DR   InterPro; IPR013320; ConA-like_dom_sf.
DR   InterPro; IPR000742; EGF-like_dom.
DR   InterPro; IPR009254; Laminin_aI.
DR   InterPro; IPR010307; Laminin_dom_II.
DR   InterPro; IPR002049; Laminin_EGF.
DR   InterPro; IPR001791; Laminin_G.
DR   InterPro; IPR000034; Laminin_IV.
DR   InterPro; IPR008211; Laminin_N.
DR   InterPro; IPR038684; Laminin_N_sf.
DR   Pfam; PF00052; Laminin_B; 2.
DR   Pfam; PF00053; Laminin_EGF; 17.
DR   Pfam; PF00054; Laminin_G_1; 4.
DR   Pfam; PF02210; Laminin_G_2; 1.
DR   Pfam; PF06008; Laminin_I; 1.
DR   Pfam; PF06009; Laminin_II; 1.
DR   Pfam; PF00055; Laminin_N; 1.
DR   SMART; SM00181; EGF; 9.
DR   SMART; SM00180; EGF_Lam; 16.
DR   SMART; SM00281; LamB; 2.
DR   SMART; SM00282; LamG; 5.
DR   SMART; SM00136; LamNT; 1.
DR   SUPFAM; SSF49899; SSF49899; 5.
DR   PROSITE; PS01248; EGF_LAM_1; 5.
DR   PROSITE; PS50027; EGF_LAM_2; 15.
DR   PROSITE; PS50025; LAM_G_DOMAIN; 5.
DR   PROSITE; PS51115; LAMININ_IVA; 2.
DR   PROSITE; PS51117; LAMININ_NTER; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000028760};
KW   Disulfide bond {ECO:0000256|PROSITE-ProRule:PRU00122,
KW   ECO:0000256|SAAS:SAAS00814887};
KW   Laminin EGF-like domain {ECO:0000256|PROSITE-ProRule:PRU00460,
KW   ECO:0000256|SAAS:SAAS00580772}; Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000028760};
KW   Repeat {ECO:0000256|SAAS:SAAS00814929};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM      7     32       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN       23    274       Laminin N-terminal. {ECO:0000259|PROSITE:
FT                                PS51117}.
FT   DOMAIN      275    331       Laminin EGF-like. {ECO:0000259|PROSITE:
FT                                PS50027}.
FT   DOMAIN      332    401       Laminin EGF-like. {ECO:0000259|PROSITE:
FT                                PS50027}.
FT   DOMAIN      402    458       Laminin EGF-like. {ECO:0000259|PROSITE:
FT                                PS50027}.
FT   DOMAIN      459    507       Laminin EGF-like. {ECO:0000259|PROSITE:
FT                                PS50027}.
FT   DOMAIN      528    710       Laminin IV type A. {ECO:0000259|PROSITE:
FT                                PS51115}.
FT   DOMAIN      744    793       Laminin EGF-like. {ECO:0000259|PROSITE:
FT                                PS50027}.
FT   DOMAIN      794    851       Laminin EGF-like. {ECO:0000259|PROSITE:
FT                                PS50027}.
FT   DOMAIN      852    904       Laminin EGF-like. {ECO:0000259|PROSITE:
FT                                PS50027}.
FT   DOMAIN      905    953       Laminin EGF-like. {ECO:0000259|PROSITE:
FT                                PS50027}.
FT   DOMAIN      954   1000       Laminin EGF-like. {ECO:0000259|PROSITE:
FT                                PS50027}.
FT   DOMAIN     1001   1046       Laminin EGF-like. {ECO:0000259|PROSITE:
FT                                PS50027}.
FT   DOMAIN     1048   1093       Laminin EGF-like. {ECO:0000259|PROSITE:
FT                                PS50027}.
FT   DOMAIN     1094   1153       Laminin EGF-like. {ECO:0000259|PROSITE:
FT                                PS50027}.
FT   DOMAIN     1168   1360       Laminin IV type A. {ECO:0000259|PROSITE:
FT                                PS51115}.
FT   DOMAIN     1407   1455       Laminin EGF-like. {ECO:0000259|PROSITE:
FT                                PS50027}.
FT   DOMAIN     1456   1514       Laminin EGF-like. {ECO:0000259|PROSITE:
FT                                PS50027}.
FT   DOMAIN     1515   1564       Laminin EGF-like. {ECO:0000259|PROSITE:
FT                                PS50027}.
FT   DOMAIN     2136   2319       LAM_G_DOMAIN. {ECO:0000259|PROSITE:
FT                                PS50025}.
FT   DOMAIN     2329   2510       LAM_G_DOMAIN. {ECO:0000259|PROSITE:
FT                                PS50025}.
FT   DOMAIN     2515   2694       LAM_G_DOMAIN. {ECO:0000259|PROSITE:
FT                                PS50025}.
FT   DOMAIN     2755   2927       LAM_G_DOMAIN. {ECO:0000259|PROSITE:
FT                                PS50025}.
FT   DOMAIN     2932   3110       LAM_G_DOMAIN. {ECO:0000259|PROSITE:
FT                                PS50025}.
FT   REGION     2691   2745       Disordered. {ECO:0000256|MobiDB-lite:
FT                                A0A096LY31}.
FT   COILED     1730   1750       {ECO:0000256|SAM:Coils}.
FT   COILED     1762   1789       {ECO:0000256|SAM:Coils}.
FT   COILED     1832   1855       {ECO:0000256|SAM:Coils}.
FT   COILED     1921   1948       {ECO:0000256|SAM:Coils}.
FT   COILED     1957   2008       {ECO:0000256|SAM:Coils}.
FT   COILED     2083   2131       {ECO:0000256|SAM:Coils}.
FT   DISULFID    297    306       {ECO:0000256|PROSITE-ProRule:PRU00460}.
FT   DISULFID    369    378       {ECO:0000256|PROSITE-ProRule:PRU00460}.
FT   DISULFID    402    414       {ECO:0000256|PROSITE-ProRule:PRU00460}.
FT   DISULFID    434    443       {ECO:0000256|PROSITE-ProRule:PRU00460}.
FT   DISULFID    478    487       {ECO:0000256|PROSITE-ProRule:PRU00460}.
FT   DISULFID    763    772       {ECO:0000256|PROSITE-ProRule:PRU00460}.
FT   DISULFID    822    831       {ECO:0000256|PROSITE-ProRule:PRU00460}.
FT   DISULFID    876    885       {ECO:0000256|PROSITE-ProRule:PRU00460}.
FT   DISULFID    888    902       {ECO:0000256|PROSITE-ProRule:PRU00460}.
FT   DISULFID    905    917       {ECO:0000256|PROSITE-ProRule:PRU00460}.
FT   DISULFID    907    924       {ECO:0000256|PROSITE-ProRule:PRU00460}.
FT   DISULFID    926    935       {ECO:0000256|PROSITE-ProRule:PRU00460}.
FT   DISULFID    954    966       {ECO:0000256|PROSITE-ProRule:PRU00460}.
FT   DISULFID    974    983       {ECO:0000256|PROSITE-ProRule:PRU00460}.
FT   DISULFID   1019   1028       {ECO:0000256|PROSITE-ProRule:PRU00460}.
FT   DISULFID   1048   1060       {ECO:0000256|PROSITE-ProRule:PRU00460}.
FT   DISULFID   1050   1067       {ECO:0000256|PROSITE-ProRule:PRU00460}.
FT   DISULFID   1069   1078       {ECO:0000256|PROSITE-ProRule:PRU00460}.
FT   DISULFID   1094   1106       {ECO:0000256|PROSITE-ProRule:PRU00460}.
FT   DISULFID   1124   1133       {ECO:0000256|PROSITE-ProRule:PRU00460}.
FT   DISULFID   1426   1435       {ECO:0000256|PROSITE-ProRule:PRU00460}.
FT   DISULFID   1485   1494       {ECO:0000256|PROSITE-ProRule:PRU00460}.
FT   DISULFID   1515   1527       {ECO:0000256|PROSITE-ProRule:PRU00460}.
FT   DISULFID   1517   1534       {ECO:0000256|PROSITE-ProRule:PRU00460}.
FT   DISULFID   1536   1545       {ECO:0000256|PROSITE-ProRule:PRU00460}.
FT   DISULFID   1548   1562       {ECO:0000256|PROSITE-ProRule:PRU00460}.
FT   DISULFID   2667   2694       {ECO:0000256|PROSITE-ProRule:PRU00122}.
SQ   SEQUENCE   3123 AA;  342262 MW;  933631EEF2D25CBD CRC64;
     AHSFSFVLLR LLVLVTSYVL LFCFSGLFPA VLNLATMADI TTNATCGTNG PEMFCKLVEH
     VPGQPVRNPQ CRICNQRSTN SFEHHPIEYA IDGTNRWWQS PSIMNGMEYH YVTVTLDLKQ
     VFQVAYVIIK AANSPRPGNW ILERSIDGVT FEPWQYYAIT DTECLTRFNI NPRTGPPSYT
     RDDEVICTSF YSKVHPLENG EIHTSLINGR PSADDPSPTL LNFTSARYIR LVFQRIRTLN
     ADLMTLTLSD PKDIDHIVTR RYYYSIKDIS VGGMCICYGH AKACPLNPAT KKFSCECEHN
     TCGESCDHCC PGYHQQPWMA GTFLTRHVCE KCNCNNKAEE CYFNQTVADL SLSLDTHGQY
     RGGGVCIGCR ENTAGINCQS CVPGYYRPTE VGADEEDPCF PCSCDPHGSI SQTCVADESQ
     ASPEAGQPAG SCWCKEGFGG LQCDRCAVGY KDYPTCERCN CRVEGSVNTD PCVTPCICKE
     NVEGENCDRC KLGFYNLQQD NRRGCEKCFC MGIASQCSSS TWNFENVSTL AGWHPVGETG
     GRVWSVHRET PSYLTIRHSD VVNDLGSAYY WNAPEIYLGN KVAAYGGDVT FTVSYKTNQQ
     EQVAIRVTSE PDLIIEGGGM KLIDNRFGQP VYPSSTSTKH VVLLPENFLV SETGQTISRR
     DFLLVLANVT SLMVRASYST ETSAVYRLHS FSMQVANPLA TGKRASAVEK CACPPGYGGL
     SCETCRPGFR RVHGKLYNGM CEPCRCHRHS SDCHEFTGHC LDCTHHTTGH HCDTCLPGYY
     GNATHGTPQD CQPCACPLNL PSNNFSPTCH LGDKGELLCD RCRPGYTGPR CDSCSNGYYG
     QPTVPGGSCQ PCSCNGNLDL SIPNSCDAIT GQCLRCRQGY DGVTCDSCAE GYYGDAMTLK
     NCQPCQCHTN GSVSEVCNKE NGQCQCREHV IGRQCDKCMP QTHGVTTGGV CIPCHCNSFG
     SKSFDCDETG QCRCQPGVTG PKCDRCSRGF FNFQEGGCTP CQCSHVGNNC DANTGQCICP
     PNTIGERCDR CAPNHWGHDI TTGCKKECGC NVIGSLTQQC NANTGCCSCR DSFRGEKCDE
     CKIGYRDFPQ CIQCECSVAG SDSQTCDMER GVCGCADRTG KCNCKQNVEG HNCDRCKTDM
     FGLSVKNPLG CSKCYCYGLT HSCMEAQGLI RMWLTLRPEQ TVLPLVDKSN TVEKRAGVSF
     QHPEILAHAE VVTTTLSEPY YWKLPEQFTG SMITAYGGQL KYAVYYEARD ETGPSSYEPQ
     VIIKGGPNHN IIITRHIPGL QIGQLTRHEI DMTEHEWRYA DGRSVSREDF MDVLFYVDYI
     LIKASHGNLM RHSRISEISL TVAEEGTPAE QNEKAHQIEK CDCPTGYSGL SCEECAAGFY
     RLRAGSPVSV PASRLPTAAG MGSCVQCQCS GHSSTCDPET SICQNCQDNT EGDHCERCAP
     GFYGVVRGSP DDCKRCACPL SNPEKSSFSP TCVAEGFSDH RCTSCAEGYE GKYCERCATG
     YHGNPRMPGG RCEECKCSSW GSLPGPCHPV TGQCRCRVGT SGILCDRCMD RHVCGPSGII
     SCDDECSGLL ISDMDRLYRI ITDVTLTTPL PPPYKALYRF ENMTEELKVK LILNKSKDHR
     HAAGSEIHPL QLNSEKVDKR MIVVQLIIDC STEDKVTHTQ AHTQASALMH KILINVRQVE
     LHSNLQSKAA ELNKTLSRKD GAPDKSLSEM KEEIQAMLAE MRKRQLGGMK SIAEEEKDLA
     EELYQKVKRL FGDPHQATED LKAEIKEKLS DHEGKLQEAQ DLLNSAQGKA RQAGSLAEQN
     KANLTALQRK RDAVNAVKQD AQKVLGEGSD LLDDANQLSD NIIKELEELE EMDRELGPLR
     AQLDDEVQGL SDGLSDGRLA EQVREAEGHA KQLNESAAIL DGILAEAKNL SFNATAAVHA
     YSNIKTNVDA AEKEAKAAKQ MANEALALAL GPEVPVKEAA QNALQKSQIL LNKAKQLQND
     VKENADDVAG LKSRVKAARD KAKDLQTAVN GTLATLRAIP NDTSAKLAAT KAVAADANAT
     AVDVLERLAD LNLHLGGLQL NSSKLEDDVN AANGMIQDPE KNIHAAGAKV KDLEDEADRL
     LEKLQPIKEL QDNLRRNISQ IKELINQARK QANSIKVSVS SGGDCLRSYR PDIRKGRYNT
     IILHVKTTTP ENLLFYLGSA KYVDFLALEM RKGKVNFLWD VGSGVGRVEY PHHTINDGNW
     HRIEASRNGL NGTISVYPLE GPMAGMMPTP ASANSPKAFT ILDVDQNAYL FVGGILGTAK
     KAEAVRASTF IGCMGETFLD GKPIGLWNYR EREGDCKGCV VSPQRTDGEG TVQLDGEGYA
     AVGRPTRWNP NVSTITFKFR TFSSDALLMY LSTEDMKDFM SLELSEGKVK VNFDLGSGVG
     RALSAKRHND GRWKALTVSR NKKQGTSTVI VVDIDDGAEE KIVALSQGSA TGLNLKENQK
     IYFGGLPTIG NYRSEVNLKR YAGCLRDIEV SRTPYNLLSS TDYTGVTKGC NVENLHTVSF
     SKPGYMELGG LTLEVGTEIS LSFSTLSDSG IILLAVGGAS PVSPSQPYLS VMLNKGSLEV
     LINTGSHNQR HVVRRPDQGN LSDGREHSLR IERLPGRSFA VQVDEEPKRE APLPNDQPIR
     LQRIFLGGIP AHVEQTSNRV NVPFQGCIWN LMVNSVLSDF SRPVSFENAE IGQCPNLAPP
     PPPPPVPEKE ETTEKKVDSK PVRPPVTPAP PKPRPGRPDE DSCASAVAPT SLEKAYQFGL
     TRNSHMTFAF DDTKVRERLI LEFELRTKEL SGLVLYMARI NHADFVSIQI KEGQACLGFD
     LGHGNISDCV PFSINDGNWH KIRVQRTKQR GVLVVEGRYM KQMFSPKTAD LLDVVGKVYV
     GGLPQNYTTK RIGPILYSIN GCIRNFTMGG SPLDMAAPTS SYMVGRCFVS TETGTYFDGT
     GYLKAVSSYR VGLDVSIAFE FRTSKTSGVL LAVSNQANDG LGLEIVDGKL LFHVDNGAGR
     ITAKHVPEGR SFCDGQWHNI TANKLRHRLE LVVDGVKSQA QSPNARSNTC DTNDPIYVGG
     YPAGVRQAAL STRSSFRGCM KNLKITKASK TMDVQFNKAL EIKGVQPLSC PARAAQHYPN
     PIN
//
DBGET integrated database retrieval system