ID A0A096LYV1_POEFO Unreviewed; 534 AA.
AC A0A096LYV1;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 39.
DE RecName: Full=AT-rich interactive domain-containing protein 3 {ECO:0000256|RuleBase:RU369100};
DE Short=ARID domain-containing protein {ECO:0000256|RuleBase:RU369100};
OS Poecilia formosa (Amazon molly) (Limia formosa).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC Poecilia.
OX NCBI_TaxID=48698 {ECO:0000313|Ensembl:ENSPFOP00000024342.1, ECO:0000313|Proteomes:UP000028760};
RN [1] {ECO:0000313|Proteomes:UP000028760}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=female {ECO:0000313|Proteomes:UP000028760};
RA Schartl M., Warren W.;
RL Submitted (OCT-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSPFOP00000024342.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- FUNCTION: Transcription factor. {ECO:0000256|RuleBase:RU369100}.
CC -!- SUBUNIT: Heterodimer with ARID3A. Interacts with unphosphorylated RB1.
CC {ECO:0000256|RuleBase:RU369100}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|RuleBase:RU369100}.
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DR EMBL; AYCK01012906; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; A0A096LYV1; -.
DR Ensembl; ENSPFOT00000028692.1; ENSPFOP00000024342.1; ENSPFOG00000015407.2.
DR GeneTree; ENSGT00940000156052; -.
DR Proteomes; UP000028760; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IEA:InterPro.
DR CDD; cd16867; ARID_ARID3; 1.
DR Gene3D; 1.10.150.60; ARID DNA-binding domain; 1.
DR InterPro; IPR045147; ARI3A/B/C.
DR InterPro; IPR001606; ARID_dom.
DR InterPro; IPR036431; ARID_dom_sf.
DR InterPro; IPR023334; REKLES_domain.
DR PANTHER; PTHR15348:SF30; AT-RICH INTERACTIVE DOMAIN-CONTAINING PROTEIN 3B ISOFORM X1; 1.
DR PANTHER; PTHR15348; AT-RICH INTERACTIVE DOMAIN-CONTAINING PROTEIN ARID DOMAIN- CONTAINING PROTEIN DEAD RINGER PROTEIN B-CELL REGULATOR OF IGH TRANSCRIPTION BRIGHT; 1.
DR Pfam; PF01388; ARID; 1.
DR SMART; SM01014; ARID; 1.
DR SMART; SM00501; BRIGHT; 1.
DR SUPFAM; SSF46774; ARID-like; 1.
DR PROSITE; PS51011; ARID; 1.
DR PROSITE; PS51486; REKLES; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|RuleBase:RU369100};
KW Nucleus {ECO:0000256|RuleBase:RU369100};
KW Reference proteome {ECO:0000313|Proteomes:UP000028760};
KW Transcription {ECO:0000256|RuleBase:RU369100};
KW Transcription regulation {ECO:0000256|RuleBase:RU369100}.
FT DOMAIN 192..284
FT /note="ARID"
FT /evidence="ECO:0000259|PROSITE:PS51011"
FT DOMAIN 394..494
FT /note="REKLES"
FT /evidence="ECO:0000259|PROSITE:PS51486"
FT REGION 23..94
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 109..177
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 297..321
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 493..534
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 57..82
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 305..321
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 504..534
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 534 AA; 57043 MW; 1668BAE9FEBB3B71 CRC64;
MYAQQVAAQQ AILAAARASG ASFMGKGMAG GVPAAGLPPR VSNQSSVDSE REEDEDRGRD
SGDEDDDNEM MEGDEGSDED EGNPSGLEFL RKQTLALQQN ASRIPARPFA GYSMSAPQRA
ASPPVRVKQE PDEGMSPAGP NSSASPNGQA DWGFEDHFRQ NGSAGWTDEA DSNRGRGEAS
RDFAKLYELD NDPKRKEFLD DLFTFMQKRG TPVNRIPIMA KQVLDLYMLY KLVTEKGGLV
EVINKKIWRE ITKGLNLPTS ITSAAFTLRT QYMKYLYPYE CERKGLSSPG ELQAAIDSNR
REGRRPSYSS SLFRFSPSPS TAPHILSPPK MHLAGLGAGT SVALNGLQAS PGPSLKKVNN
LEDLTPAIMA ARPPLALSLG QQQVAGLARA ATLEQLREKL ETSGGGEGPE RKMARLAEEQ
QRLMQQAFQH NLLAMASQMP MNLRLGAPTI TTRDEKQQDM SLSISTNGNA SITVSVEVNG
TIYSGTLFAQ KSGGAPGPVV AASAASAQTL SPTPSSTSSS KGSGSAELAP SSSP
//
