ID A0A096M0Q7_POEFO Unreviewed; 774 AA.
AC A0A096M0Q7;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE SubName: Full=G protein-coupled receptor 156 {ECO:0000313|Ensembl:ENSPFOP00000024998.1};
GN Name=GPR156 {ECO:0000313|Ensembl:ENSPFOP00000024998.1};
OS Poecilia formosa (Amazon molly) (Limia formosa).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC Poecilia.
OX NCBI_TaxID=48698 {ECO:0000313|Ensembl:ENSPFOP00000024998.1, ECO:0000313|Proteomes:UP000028760};
RN [1] {ECO:0000313|Proteomes:UP000028760}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=female {ECO:0000313|Proteomes:UP000028760};
RA Schartl M., Warren W.;
RL Submitted (OCT-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSPFOP00000024998.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the G-protein coupled receptor 3 family. GABA-B
CC receptor subfamily. {ECO:0000256|ARBA:ARBA00008991}.
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DR EMBL; AYCK01020923; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; A0A096M0Q7; -.
DR Ensembl; ENSPFOT00000031993.1; ENSPFOP00000024998.1; ENSPFOG00000007604.2.
DR GeneTree; ENSGT00940000159755; -.
DR Proteomes; UP000028760; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0004965; F:G protein-coupled GABA receptor activity; IEA:InterPro.
DR CDD; cd15292; 7tmC_GPR156; 1.
DR InterPro; IPR002455; GPCR3_GABA-B.
DR InterPro; IPR017978; GPCR_3_C.
DR InterPro; IPR041946; GPR156_7TM.
DR PANTHER; PTHR10519:SF63; G-PROTEIN COUPLED RECEPTOR 156-RELATED; 1.
DR PANTHER; PTHR10519; GABA-B RECEPTOR; 1.
DR Pfam; PF00003; 7tm_3; 1.
DR PRINTS; PR01176; GABABRECEPTR.
DR PROSITE; PS50259; G_PROTEIN_RECEP_F3_4; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW G-protein coupled receptor {ECO:0000256|ARBA:ARBA00023040};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Receptor {ECO:0000256|ARBA:ARBA00023170};
KW Reference proteome {ECO:0000313|Proteomes:UP000028760};
KW Transducer {ECO:0000256|ARBA:ARBA00023224};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 55..78
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 90..108
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 128..147
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 167..187
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 263..285
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 291..313
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 53..316
FT /note="G-protein coupled receptors family 3 profile"
FT /evidence="ECO:0000259|PROSITE:PS50259"
FT REGION 410..514
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 741..762
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 359..393
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 410..437
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 455..510
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 774 AA; 86154 MW; 329C1EAA92349B88 CRC64;
MEPELNCSSV CDSPLCLIQA GLSRQEGQDV LRRLCILNSL AAEVPRRSLS PALRAVVWTM
LSSGILLAFC FLVFTLRFKN NRIVKMSSPN LNVLTLLGSV LTYISGFLFA MDERAHAQAE
FSLLQARMWM LCVGSTLVFG PILGKTWRLY RVFTQRVPDK RVIIRDIQLI GMVVLLILLE
ILILTTWNLT DPVRCSQSVR AVAKATERDT SYSLSQLDSC SSEYSNIWLI IIAVQKGCLL
LYGTYLAGLT SNVSHPPVNQ SPTIITAVTL VTFSSAVAFP VFFFLHAWPN LVYSTVAGAI
FICTLATNCM LFVPQLTQWR QFEEDQNNPS QMAKYFSSPS KSQPSVYSQD EIYFLLGENS
SMKKLLNEKN AAIDSLQEQV NNAKDKLLRL MTASQPLGDQ DVDSSAAYLN SSSTQTTELP
SEGSSSSCLS QGDTKSRRLP PPSPHNLTLP PDPSNVLRIP SSQNSMDLHP ASSPFTDDIL
SGSRKDVPNS ATRETAQSTV RGNAKQPLSP TFPGRTAEEA VHFVTSLHSE KLQEIIQELS
MDAVLETALR FPGQASKTSS QPRLNTLSPL SLCSSHSLFQ YPSVSPHAVR KRRPPFHPSR
RALSSSCFYT GSDVPICELK RDTCEHQNPD ETHFRADCSV TDLDKSVEEK EGDKEEEEEA
KNCQRHASRS HNCPLWRCAR QNCSPEHGAE EDDSGKQRHR CIRDSSGYWD SDSSSSTDYC
YYHRPYCDSC LQRGSFLSSD SSSDSSDSEY EDYTNLCRPP RPVVFKDDLK PTLV
//
