ID A0A096M0V0_POEFO Unreviewed; 1762 AA.
AC A0A096M0V0;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 44.
DE SubName: Full=Fer-1 like family member 6 {ECO:0000313|Ensembl:ENSPFOP00000025041.1};
GN Name=FER1L6 {ECO:0000313|Ensembl:ENSPFOP00000025041.1};
OS Poecilia formosa (Amazon molly) (Limia formosa).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC Poecilia.
OX NCBI_TaxID=48698 {ECO:0000313|Ensembl:ENSPFOP00000025041.1, ECO:0000313|Proteomes:UP000028760};
RN [1] {ECO:0000313|Proteomes:UP000028760}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=female {ECO:0000313|Proteomes:UP000028760};
RA Schartl M., Warren W.;
RL Submitted (OCT-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSPFOP00000025041.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR EMBL; AYCK01012947; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR Ensembl; ENSPFOT00000026566.1; ENSPFOP00000025041.1; ENSPFOG00000018519.2.
DR GeneTree; ENSGT00940000159069; -.
DR OMA; SPNEDMM; -.
DR Proteomes; UP000028760; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd04011; C2B_Ferlin; 1.
DR CDD; cd04018; C2C_Ferlin; 1.
DR CDD; cd04017; C2D_Ferlin; 1.
DR CDD; cd04037; C2E_Ferlin; 1.
DR CDD; cd08374; C2F_Ferlin; 1.
DR Gene3D; 2.60.40.150; C2 domain; 5.
DR InterPro; IPR000008; C2_dom.
DR InterPro; IPR035892; C2_domain_sf.
DR InterPro; IPR037720; C2B_Ferlin.
DR InterPro; IPR037722; C2C_Ferlin.
DR InterPro; IPR037723; C2D_Ferlin.
DR InterPro; IPR037724; C2E_Ferlin.
DR InterPro; IPR037725; C2F_Ferlin.
DR InterPro; IPR012968; FerIin_dom.
DR InterPro; IPR037721; Ferlin.
DR InterPro; IPR012561; Ferlin_B-domain.
DR InterPro; IPR032362; Ferlin_C.
DR PANTHER; PTHR12546; FER-1-LIKE; 1.
DR PANTHER; PTHR12546:SF37; FER-1-LIKE 6 (C. ELEGANS); 1.
DR Pfam; PF00168; C2; 5.
DR Pfam; PF08150; FerB; 1.
DR Pfam; PF08151; FerI; 1.
DR Pfam; PF16165; Ferlin_C; 1.
DR SMART; SM00239; C2; 6.
DR SMART; SM01201; FerB; 1.
DR SMART; SM01202; FerI; 1.
DR SUPFAM; SSF49562; C2 domain (Calcium/lipid-binding domain, CaLB); 6.
DR PROSITE; PS50004; C2; 5.
PE 4: Predicted;
KW Calcium {ECO:0000256|ARBA:ARBA00022837};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000028760};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 1730..1751
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 1..119
FT /note="C2"
FT /evidence="ECO:0000259|PROSITE:PS50004"
FT DOMAIN 160..291
FT /note="C2"
FT /evidence="ECO:0000259|PROSITE:PS50004"
FT DOMAIN 761..887
FT /note="C2"
FT /evidence="ECO:0000259|PROSITE:PS50004"
FT DOMAIN 923..1046
FT /note="C2"
FT /evidence="ECO:0000259|PROSITE:PS50004"
FT DOMAIN 1249..1368
FT /note="C2"
FT /evidence="ECO:0000259|PROSITE:PS50004"
FT REGION 362..406
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 480..510
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1042..1070
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1082..1120
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1100..1115
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1762 AA; 197172 MW; D5A1F81F55622D45 CRC64;
RAKLQTRIQD SEGKPESFQI GINITEARQL VGENIDPSVV IEIGDEKKQT SVKEGTNAPF
YNEYFVFDFF AHKEIFLDKV IKLTVVHSKM LKTFCVGSFK LDVWTVYKQP GHQFVNKWAM
LTNPGDISTG VKGYVKCDIS VSAKGDAVQP GQKASDAEEQ IEKNLLIPEG LPSERPWARF
CVKVYRAEGL PRNNSSIMAN VTKAFIGDNT ALIDPYVVVS FFKQVGRTST QKSSADPVWN
EQIVFTEMFP PLCQRLKIQV WDEGSMNDVA IGTHYFDLRR ISNEQDGDKG FLPTFGPAWI
NLYGSARNFS LGDDTGELNE GIGEGVSFRG RVYLELTVEI LSGGTGSDSK LSRMIKPVKD
AKAGKAGGKD AKSSAGGGAG GGAGAADDDK GKAGAAEVLP VDPPPVVPAE DDETFLLFGA
LFEATMIDRK IGDKPISFEF SLGNHGNVLE SSVQPSAASP AVTRRRKVLD LPDSSDIFGS
SLTVPSSPLL PRDPSDSCGA SKSATPPEKP LIVEGNRHYM YLPLEKKKPC ASVVSSWEDR
TYRLYNSNML ENIAVLFEEG VCVAADLHKK LDPAAEAALR AALRDFCLDA RNFIATAEAK
LKAELKSSYL TILDKKRLTM CKQELESMVG EAEMLGERKT AARGVKEMLE EATKLAQKLR
FLVEEPQHTV PDMFVWLLSN NKRVAYARLR TRDLLYSSNR EARGILCGKI VTLFLKPPGK
RPAALSVQAK LDVYLWFGAC SDSSHMLDDL PAGYSRATEG ADTNSPPSYL LCMEQHKFQL
RCHMYQARGL IAADNTGLSD PFARVTFLSH SQTTNIISQT LSPTWNHCLP MSSVLLSGDL
QHIQEEPPHV VVEVYDDDAL GKAEYLGATV AVPEVRLASE PYTPPLLQYS PLHCGSQSGG
DLLAAFELLQ SGQMSLPELE EQEGGIYTVP ANIRPVLSTY RLEVLFWGLR ELKKVQLLSV
DRPQVFIECA GKTLRSSVIQ KYKSNPNFTT LLDAIELELP ENEHLHPPLS ITVVDWRAFG
RSTLVGNHII NNLKAFKYTP PPTPPHTVQL HKPPEVTHTP RPEAMETRST VTLTNQDFLI
TVEDEAPLPA PPTPRPQPKK KKERSSKSIH RSTKRRRRTI ADESAESVID WWSKYYASVD
KQAKQKDSFQ LPSVFDKDGD KKKKQKGKET LELSYVLPTK IAKLQLYSKE LEAEFGPFDD
WVSTYELFRG KANEDEGTSD ERFVGKFKGR FCLYKLSDED EEDGEDVVDT GHYRVNRGIP
PNTSVQVLIR VYIVSASNLH PADPDGKADP YIFLRLGKNE IKDRDNYIPK QLNPVFGRSF
EMQATFPQES LLSLLIYDYD LVGGDDLIGE TRIDLENRFY SRHRATCGLP SEYSLGGYNA
WRDSLKPSEL LAKMCRDNGV DGPHFSPGRI TVADKVFTGK TLYMHDDEPV ESYEHLSLKV
LHRWAEIPAV GCKLVPEHIE TRTLYNKARP GMDQQGQVQM WVDMFPMDLP HPGPPVDISP
RKPKGYELRI IIWNTEDVIL EDTNFLTGQQ SSDIYIKGWL KGLEDDRQET DVHYNSLTGE
GNFNWRFVFP FSYLPAEKVV VVKKREHIFS LDKTEQKLPA ILILQVWDFE TLSSLELDLH
AFPRGAKTAK SCKADMLTEV TDRISIFQQK RARGWWPFSK SGELTVPPPG KVEAEFHLVT
AEEAEKNPVG KARKEPEPLP KPNRPDTSFS WFVNPFKCFF HLVWRNYKKY IIIALVLLIT
VLFLALLFYT LPGAISQKII NG
//
