ID A0A096M0W4_POEFO Unreviewed; 923 AA.
AC A0A096M0W4;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE SubName: Full=SLIT and NTRK-like protein 3 {ECO:0000313|Ensembl:ENSPFOP00000025055.1};
GN Name=SLITRK3 {ECO:0000313|Ensembl:ENSPFOP00000025055.1};
OS Poecilia formosa (Amazon molly) (Limia formosa).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC Poecilia.
OX NCBI_TaxID=48698 {ECO:0000313|Ensembl:ENSPFOP00000025055.1, ECO:0000313|Proteomes:UP000028760};
RN [1] {ECO:0000313|Proteomes:UP000028760}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=female {ECO:0000313|Proteomes:UP000028760};
RA Schartl M., Warren W.;
RL Submitted (OCT-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSPFOP00000025055.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the SLITRK family.
CC {ECO:0000256|ARBA:ARBA00010439}.
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DR EMBL; AYCK01019250; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; A0A096M0W4; -.
DR Ensembl; ENSPFOT00000025496.1; ENSPFOP00000025055.1; ENSPFOG00000000811.2.
DR GeneTree; ENSGT00940000158681; -.
DR Proteomes; UP000028760; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0007409; P:axonogenesis; IEA:InterPro.
DR GO; GO:1905606; P:regulation of presynapse assembly; IEA:InterPro.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 2.
DR InterPro; IPR000483; Cys-rich_flank_reg_C.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR043326; Slitrk.
DR PANTHER; PTHR45773:SF9; SLIT AND NTRK-LIKE FAMILY, MEMBER 3B; 1.
DR PANTHER; PTHR45773; SLIT AND NTRK-LIKE PROTEIN 4-RELATED; 1.
DR Pfam; PF13855; LRR_8; 2.
DR SMART; SM00369; LRR_TYP; 10.
DR SMART; SM00082; LRRCT; 2.
DR SUPFAM; SSF52058; L domain-like; 2.
DR PROSITE; PS51450; LRR; 2.
PE 3: Inferred from homology;
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000028760};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..18
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 19..923
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5001919704"
FT TRANSMEM 670..694
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 221..271
FT /note="LRRCT"
FT /evidence="ECO:0000259|SMART:SM00082"
FT DOMAIN 573..623
FT /note="LRRCT"
FT /evidence="ECO:0000259|SMART:SM00082"
FT REGION 276..374
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 850..923
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 314..333
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 334..348
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 350..373
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 873..893
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 899..915
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 923 AA; 102700 MW; D30AD3547057BF74 CRC64;
MQWVTLVVAL GCARLSQASP LVDNSEEEVD EPCFEPCTCE VKEGVLHVHC DGRGFTNASQ
VSQSWIRPFK LNLQRNSFRR LYSNGFQHLG NAVSMNLGNN ALQDIRVGAF NGLAKLKRLY
LHENKLEVFR NDTFAGLEAL EYLQADYNVI KRIDSGALRF LYKLRVLILN DNLIPVLPAH
LFRSVSLTHL DLRGNRLKSL AKDGTLQYIG RSLMELQLEE NPWNCSCEAV ELLQWLGQIP
YTAVVGDVTC EYPFHLHGKD LREIPRKELC ADLPDKEHQG ERGAPSAGSQ PQPLPPNSKH
NSHPGRARPT RPSSMVHGSR QNTLASSTSS PYTSAERKER EKQLKPTKRP RSSNRTPPTA
RSLMPNQNPP VAGYQTRPPI PIICPIRCTC NLHIADLGQT LNCKENGFRN MSQLIPRPLN
GRKLFLGGNF IQKLVRSDFW NFSSLDLIHF GNNRISFIQE GAFSSLVNLR TLHLNENELD
RLSPHMFLGL QNLRFLYLEN NKIGVVDPGT FDSMPSLELL FLNYNALRSL PVGVFSGVKL
SRLNLRNNVF QHLPVEGVLE HLRGLVQVDL QQNPWECNCE AAALKRWLEG LSTMILMGEA
VCKSPEKTQG VALRSLSMEL LCPELEPQEA RELEEQMANS TDAGGNVSVY PTPGLGPLAP
PWIDSIPLSV LVLSLLVLFV SAFFAAAALI AYALRVREKL PFRRQGEVDL AGIQMECGIF
TEQPEKPPLP LAEHNHVYDT ILPREAAAKG ADPAASHMCS NPMFKDQQDV DVFAASKECK
GGYCPTPEKE KEWTLEVSSS PINTITGAMG ALAGLHGNGI LCPTVIDSQG PTPKVELVDC
LFQLPTPEFR DLPDRYGRPP PCYPRTQDSK QEVRPDQTLV VTTASSSAGG GHGGQSEQGD
GEQRPRLRTK PDYMEVLDRS YQF
//
