ID A0A096M4F3_POEFO Unreviewed; 612 AA.
AC A0A096M4F3;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 24-JAN-2024, entry version 33.
DE SubName: Full=GRAM domain containing 4 {ECO:0000313|Ensembl:ENSPFOP00000026294.1};
GN Name=GRAMD4 {ECO:0000313|Ensembl:ENSPFOP00000026294.1};
OS Poecilia formosa (Amazon molly) (Limia formosa).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC Poecilia.
OX NCBI_TaxID=48698 {ECO:0000313|Ensembl:ENSPFOP00000026294.1, ECO:0000313|Proteomes:UP000028760};
RN [1] {ECO:0000313|Proteomes:UP000028760}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=female {ECO:0000313|Proteomes:UP000028760};
RA Schartl M., Warren W.;
RL Submitted (OCT-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSPFOP00000026294.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR EMBL; AYCK01001424; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AYCK01001425; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AYCK01001426; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AYCK01001427; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; A0A096M4F3; -.
DR STRING; 48698.ENSPFOP00000026294; -.
DR Ensembl; ENSPFOT00000026760.1; ENSPFOP00000026294.1; ENSPFOG00000009239.2.
DR eggNOG; ENOG502QPMR; Eukaryota.
DR GeneTree; ENSGT00390000010968; -.
DR OMA; XYLCFES; -.
DR Proteomes; UP000028760; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0006915; P:apoptotic process; IEA:InterPro.
DR CDD; cd13221; PH-GRAM_GRAMDC4; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR004182; GRAM.
DR InterPro; IPR037847; GRAMDC4.
DR InterPro; IPR037845; GRAMDC4_PH-GRAM.
DR InterPro; IPR011993; PH-like_dom_sf.
DR PANTHER; PTHR37402; GRAM DOMAIN-CONTAINING PROTEIN 4; 1.
DR PANTHER; PTHR37402:SF1; GRAM DOMAIN-CONTAINING PROTEIN 4; 1.
DR Pfam; PF02893; GRAM; 1.
DR SMART; SM00568; GRAM; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils}; Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000028760};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 278..298
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 368..384
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 475..555
FT /note="GRAM"
FT /evidence="ECO:0000259|SMART:SM00568"
FT REGION 39..97
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 161..189
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 452..473
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 111..161
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 61..79
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 612 AA; 70335 MW; 1F8264D277E28C6D CRC64;
MKLCYDLRAG VAVRHVKVKP RCAVLTMLKR LDKIRFRGPR SRDDFPDLGE SPPASDTECN
DDVPPKPRAA PRDTEDVLRD PAGSGSPTMA AAVQDFQRSE SERLSEVKGH LEIALLEKHF
LQEELRKLRE ETNVDSLRQE LERERSKRLD LEQKMNEVLR TRLEDSPPQP PRKQQSPSNN
GTAEKRQQKE VWSSRLQKWL YERFGVYIED FRFQPEESTV ETEEPLSAKR LTENMRRLKR
GARPVTNFLR NLSALSNWHS VYTSAIAFII YMNAAWHGWA IPMFLFLAIL RLSLNYLIAR
GWRIQWSIVP EVSEPMEPPK EDLTVSEKFQ LVLDVAQKAQ NIFGKMADVL EKIKNLFMWV
QPDSTRKLYI CLWVAFIFSC VLPYKLMGFM MGVYAGIKFF IIDFLFKSCP KLRDKYDTPY
IVWNSLPTDP QLKERTNATV SRRVQPVVSR SSLATVPSGM SREDDAGRSH STKKGPFHEI
FNLPETERPL AVCENGWRCC LINRDRKMPT DYIRNGVLYV TENYLCFESS SSKSSASKKN
KVIKLVDITD IQKYKVLSVL PGSGMGISIA TPSTQKPLVF GAMIHRDEAF ETIFTQYMKI
VTTSKPPSST EL
//
