ID   A0A096M4T5_POEFO        Unreviewed;       623 AA.
AC   A0A096M4T5;
DT   26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT   26-NOV-2014, sequence version 1.
DT   27-MAR-2024, entry version 33.
DE   RecName: Full=HECT domain-containing protein {ECO:0000259|Pfam:PF00632};
OS   Poecilia formosa (Amazon molly) (Limia formosa).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC   Poecilia.
OX   NCBI_TaxID=48698 {ECO:0000313|Ensembl:ENSPFOP00000026426.1, ECO:0000313|Proteomes:UP000028760};
RN   [1] {ECO:0000313|Proteomes:UP000028760}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=female {ECO:0000313|Proteomes:UP000028760};
RA   Schartl M., Warren W.;
RL   Submitted (OCT-2013) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSPFOP00000026426.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
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DR   EMBL; AYCK01007831; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   AlphaFoldDB; A0A096M4T5; -.
DR   Ensembl; ENSPFOT00000023727.1; ENSPFOP00000026426.1; ENSPFOG00000022067.1.
DR   eggNOG; ENOG502RXSA; Eukaryota.
DR   GeneTree; ENSGT00770000121698; -.
DR   OMA; DNRAQTQ; -.
DR   Proteomes; UP000028760; Unassembled WGS sequence.
DR   GO; GO:0004842; F:ubiquitin-protein transferase activity; IEA:InterPro.
DR   Gene3D; 3.30.2410.10; Hect, E3 ligase catalytic domain; 1.
DR   Gene3D; 3.90.1750.10; Hect, E3 ligase catalytic domains; 1.
DR   InterPro; IPR000569; HECT_dom.
DR   InterPro; IPR035983; Hect_E3_ubiquitin_ligase.
DR   Pfam; PF00632; HECT; 1.
DR   SUPFAM; SSF56204; Hect, E3 ligase catalytic domain; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000028760};
KW   Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786}.
FT   DOMAIN          362..620
FT                   /note="HECT"
FT                   /evidence="ECO:0000259|Pfam:PF00632"
FT   REGION          265..285
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   623 AA;  70701 MW;  0AE5AEA7E8C7CD4B CRC64;
     TPLLRFLRNR GVPEECLSRM EEEHIDATVI DCMDDGTLSE YIPTYGDRIA ARRFWRKMGL
     ESSDENLDQA DTSTTTRTRT NAQSNKCALK KTRRIDLGWI HDGKQVRTRK GGGTRTIDVP
     KDTKKSDLIN YSKELFFPNG KCRFGSLETL NYDILDFQEE AVLDESITVG ELYSLVRLGR
     LRFYFSTTSK INLQGEESEG NDVQTIDLDE NDQESEPLFN LSSDLDESEV TFGPVSNAEP
     IPGELDDTII YQFEGDEQDF ISLEIPNTNT SGNRLSPASN DEGSTSAASN EIVCITIKLH
     RSNLLEEMIT QFKDKILLRQ TLKFCFIDEK GADADGVSRD VYTTFWTEFM EHIGEGEEVR
     VPSLPNRWQK QEWKSIGRIL LKGFKDHGYF PCRLAPAFTV ALIFGESEVS EEMLFESLLL
     YITQSDRDLV SNVLKSGCPD EDRDELVDLL DRLNVTALPT QDNLKGLLLS AAHKHLIQKP
     RYAAEQMSST ASHILKESFC SPQALLQMYQ EKKPTTKRFL KLLEASPTTQ AESQSFRFLQ
     QYIRGLDDPG LRRMLRFVTG SDMICVNKVE VIFTPLEGLA RRPIAHTCGP ALELPWTYGS
     YPELCCEMDS ILLNQNSFEF SIV
//