ID A0A096M5S6_POEFO Unreviewed; 891 AA.
AC A0A096M5S6;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 24-JAN-2024, entry version 46.
DE SubName: Full=Seizure related 6 homolog like 2 {ECO:0000313|Ensembl:ENSPFOP00000026767.1};
GN Name=SEZ6L2 {ECO:0000313|Ensembl:ENSPFOP00000026767.1};
OS Poecilia formosa (Amazon molly) (Limia formosa).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC Poecilia.
OX NCBI_TaxID=48698 {ECO:0000313|Ensembl:ENSPFOP00000026767.1, ECO:0000313|Proteomes:UP000028760};
RN [1] {ECO:0000313|Proteomes:UP000028760}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=female {ECO:0000313|Proteomes:UP000028760};
RA Schartl M., Warren W.;
RL Submitted (OCT-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSPFOP00000026767.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00302}.
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DR EMBL; AYCK01009482; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; A0A096M5S6; -.
DR Ensembl; ENSPFOT00000028003.1; ENSPFOP00000026767.1; ENSPFOG00000009065.2.
DR GeneTree; ENSGT00940000160492; -.
DR OMA; DPGFQIR; -.
DR Proteomes; UP000028760; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd00033; CCP; 5.
DR CDD; cd00041; CUB; 2.
DR Gene3D; 2.10.70.10; Complement Module, domain 1; 5.
DR Gene3D; 2.60.120.290; Spermadhesin, CUB domain; 3.
DR InterPro; IPR000859; CUB_dom.
DR InterPro; IPR035914; Sperma_CUB_dom_sf.
DR InterPro; IPR035976; Sushi/SCR/CCP_sf.
DR InterPro; IPR000436; Sushi_SCR_CCP_dom.
DR PANTHER; PTHR45656; PROTEIN CBR-CLEC-78; 1.
DR PANTHER; PTHR45656:SF2; SEIZURE 6-LIKE PROTEIN 2; 1.
DR Pfam; PF00431; CUB; 1.
DR Pfam; PF00084; Sushi; 5.
DR SMART; SM00032; CCP; 5.
DR SMART; SM00042; CUB; 3.
DR SUPFAM; SSF57535; Complement control module/SCR domain; 5.
DR SUPFAM; SSF49854; Spermadhesin, CUB domain; 3.
DR PROSITE; PS01180; CUB; 2.
DR PROSITE; PS50923; SUSHI; 5.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00302}; Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000028760};
KW Signal {ECO:0000256|SAM:SignalP};
KW Sushi {ECO:0000256|PROSITE-ProRule:PRU00302};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..20
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 21..891
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5001919900"
FT TRANSMEM 821..843
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 247..306
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 309..423
FT /note="CUB"
FT /evidence="ECO:0000259|PROSITE:PS01180"
FT DOMAIN 426..487
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 489..600
FT /note="CUB"
FT /evidence="ECO:0000259|PROSITE:PS01180"
FT DOMAIN 604..663
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 665..729
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 732..793
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT REGION 95..116
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT DISULFID 634..661
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00302"
FT DISULFID 667..710
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00302"
SQ SEQUENCE 891 AA; 97665 MW; 631FF9EF5DA72BAD CRC64;
MGFAHLAVMF SVTMMHMVSG MTFMTPESDT SPTSAPDSYP PGELIHAALQ SKEYLGQVSG
GSGTTTNPTQ AVPGLGMAES TATAISPGLL TTALGSSSAA GKTGSRSPMS SFPLEEETTT
TLITTTTITT MHMPVQCNAT MSAMEDFVES PDPGSSSSFS TLECTYSITV YPGYGVEIQV
RKTNLSKEES LVIMGHGGVG PELLANETLM KEGQVIRSTT NQVSIHYRSL RQSNHGTFSL
HYQAFLLSCP FPTSPEGGGV TVTDIHPGGQ AHFHCDPGFQ IRGHEVATCV NTTQPHWSTH
EPQCVVVSCG GWVRNATVGR ILSPPPPPVS NHSNGNNLSC HWLIEAKEGH RLHLHFERIA
LDEDDDRLLV RSGNSSLSHL LFDSDLDDVP ERGLLSEGST LYLELIADSS SIPLLLALRY
EAFDDEHCWE PYMPHGNFSS SDISYQLGTI VTFSCSPGFV MEQGSGTIEC VDPSNPHWND
SEPVCRALCG GELTEPSGTI LSPDWPQSYS KGLDCIWQIH GNEEKRIELE VQILNIRHTD
VLTVFDGHDV MSHVIGQYMG SKERFQIVSG GSEVTIQFQS DPDDSSFILS QGFLIHYREI
SKTNYCPTLP QIEFGWISSS HSSPVRGSVL TYQCQPGYDI SGSDIITCQW DLSWSSAPPT
CVKVQQCPDP GEVVNGARSV RPEAGFALGT VVRFSCNQGY QLEGPSQISC YGRDTGTPKW
SDRSPKCVLK YDPCPNPGVP DNGYQTLYKH SYQAGETLRF FCYEGYELIG EVIITCVPGH
PSQWNSPPPF CKVAYEELLD DHKSEVSQSF EPSRQILSEN IALAIILPII LVILLIGGIY
MYYTNICRLE WKPLFWKSLS HTHSYSPITV ESDFNNPLYE AGDTREYEVS I
//
