ID   A0A096M9D8_POEFO        Unreviewed;       790 AA.
AC   A0A096M9D8;
DT   26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT   26-NOV-2014, sequence version 1.
DT   27-MAR-2024, entry version 35.
DE   SubName: Full=HHIP-like protein 1 {ECO:0000313|Ensembl:ENSPFOP00000028029.1};
OS   Poecilia formosa (Amazon molly) (Limia formosa).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC   Poecilia.
OX   NCBI_TaxID=48698 {ECO:0000313|Ensembl:ENSPFOP00000028029.1, ECO:0000313|Proteomes:UP000028760};
RN   [1] {ECO:0000313|Proteomes:UP000028760}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=female {ECO:0000313|Proteomes:UP000028760};
RA   Schartl M., Warren W.;
RL   Submitted (OCT-2013) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSPFOP00000028029.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
CC   -!- SIMILARITY: Belongs to the HHIP family.
CC       {ECO:0000256|ARBA:ARBA00010658}.
CC   -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC       feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00196}.
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DR   EMBL; AYCK01009603; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   AlphaFoldDB; A0A096M9D8; -.
DR   Ensembl; ENSPFOT00000021818.1; ENSPFOP00000028029.1; ENSPFOG00000003253.2.
DR   GeneTree; ENSGT00940000164056; -.
DR   Proteomes; UP000028760; Unassembled WGS sequence.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0016020; C:membrane; IEA:InterPro.
DR   Gene3D; 3.10.250.10; SRCR-like domain; 1.
DR   Gene3D; 2.120.10.30; TolB, C-terminal domain; 1.
DR   InterPro; IPR011042; 6-blade_b-propeller_TolB-like.
DR   InterPro; IPR018143; Folate_rcpt-like.
DR   InterPro; IPR012938; Glc/Sorbosone_DH.
DR   InterPro; IPR011041; Quinoprot_gluc/sorb_DH.
DR   InterPro; IPR001190; SRCR.
DR   InterPro; IPR017448; SRCR-like_dom.
DR   InterPro; IPR036772; SRCR-like_dom_sf.
DR   PANTHER; PTHR19328; HEDGEHOG-INTERACTING PROTEIN; 1.
DR   PANTHER; PTHR19328:SF58; HHIP-LIKE PROTEIN 1; 1.
DR   Pfam; PF03024; Folate_rec; 1.
DR   Pfam; PF07995; GSDH; 1.
DR   Pfam; PF00530; SRCR; 1.
DR   PRINTS; PR00258; SPERACTRCPTR.
DR   SMART; SM00202; SR; 1.
DR   SUPFAM; SSF50952; Soluble quinoprotein glucose dehydrogenase; 1.
DR   SUPFAM; SSF56487; SRCR-like; 1.
DR   PROSITE; PS50287; SRCR_2; 1.
PE   3: Inferred from homology;
KW   Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW   ProRule:PRU00196}; Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW   Reference proteome {ECO:0000313|Proteomes:UP000028760};
KW   Secreted {ECO:0000256|ARBA:ARBA00022525};
KW   Signal {ECO:0000256|ARBA:ARBA00022729}.
FT   DOMAIN          687..790
FT                   /note="SRCR"
FT                   /evidence="ECO:0000259|PROSITE:PS50287"
FT   REGION          652..686
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        652..666
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   DISULFID        759..769
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
SQ   SEQUENCE   790 AA;  88923 MW;  21C661A961AE5452 CRC64;
     YLFTFWVWRG SCHPQCLDYK PPFGPQQPLV FCTDYTKFGC CDLQKDEEIS RKYDLIMENF
     DTLGSARCGK YISSILCQEC SPYAAHLYDA EDANTQMRVL PGLCGDYCSD YWRDCRYTLS
     LLLEDKGNLQ QFANLTAAIE EDRRRFCDFL ELKDKQYCYP NVLTDAELNA NLGLVREDST
     GCLEVCLQEV ANGLRNPVAM IHADDGSHRF FVAEQLGYVW VYLANGSRID HPFLNLTKAV
     LTSRWTGDER GFLCIALHPR FTTVRKAYVY YSVSVKKEER IRISEFTLSD HDDNQLDHSS
     ERMILEVVEP ASNHNGGQLL FGHDGYLYIF IGDGGRAGDP FGKFGNSQNK SALLGKVLRI
     DIDNIDESTP YTIPSDNPFV GEQGARPEIY AYGVRNMWRC SIDRGDPATG AGRGRMFCGD
     VGQNKYEEID LIVKGGNYGW RAKEGFSCYD RKLCQNSSLD DILPIFDYPH KLGKSVTGGY
     VYRGCEMPNL NGLYIFGDFM SGRLMSLKEN EATGEWQYNE ICMGRDQTCK FPKLINSYYR
     YIISFAEDEA GELYFLSTGV PSATARSGVI YKIVDPSRLC RRAPPGKCSI KPRPVKIKGK
     LIHFYPREGL IGFYLVSYQA VQIVNGKPLI LTLKAQFKVI IDTTQSKSLT TTWAPYTSQT
     ANKPPETPRG RGNKRGKGGR RLPSGSVRLV SADGMPDRGR VEIFIRGEWG TVCDDLFTRK
     AGTVVCRQLG FTTALTVMKR AALGEASSRV RILLDDVECE GEERSLLECK RSKVGKHNCS
     HEEDVGVICG
//