ID   A0A096MCV1_POEFO        Unreviewed;      1098 AA.
AC   A0A096MCV1;
DT   26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT   26-NOV-2014, sequence version 1.
DT   27-MAR-2024, entry version 37.
DE   SubName: Full=Leptin receptor {ECO:0000313|Ensembl:ENSPFOP00000029242.1};
OS   Poecilia formosa (Amazon molly) (Limia formosa).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC   Poecilia.
OX   NCBI_TaxID=48698 {ECO:0000313|Ensembl:ENSPFOP00000029242.1, ECO:0000313|Proteomes:UP000028760};
RN   [1] {ECO:0000313|Proteomes:UP000028760}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=female {ECO:0000313|Proteomes:UP000028760};
RA   Schartl M., Warren W.;
RL   Submitted (OCT-2013) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSPFOP00000029242.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
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DR   EMBL; AYCK01004136; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AYCK01004137; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   AlphaFoldDB; A0A096MCV1; -.
DR   Ensembl; ENSPFOT00000030894.1; ENSPFOP00000029242.1; ENSPFOG00000010242.2.
DR   GeneTree; ENSGT00730000111209; -.
DR   OMA; FPPHCLF; -.
DR   Proteomes; UP000028760; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   CDD; cd00063; FN3; 1.
DR   Gene3D; 2.60.40.10; Immunoglobulins; 4.
DR   InterPro; IPR003961; FN3_dom.
DR   InterPro; IPR036116; FN3_sf.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR041182; LEP-R_IGD.
DR   PANTHER; PTHR23037; CYTOKINE RECEPTOR; 1.
DR   PANTHER; PTHR23037:SF41; CYTOKINE RECEPTOR-LIKE FACTOR 2-RELATED; 1.
DR   Pfam; PF00041; fn3; 1.
DR   Pfam; PF18589; ObR_Ig; 1.
DR   SMART; SM00060; FN3; 2.
DR   SUPFAM; SSF49265; Fibronectin type III; 1.
DR   PROSITE; PS50853; FN3; 2.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000028760};
KW   Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   SIGNAL          1..21
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           22..1098
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5001920346"
FT   TRANSMEM        800..821
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          202..298
FT                   /note="Fibronectin type-III"
FT                   /evidence="ECO:0000259|PROSITE:PS50853"
FT   DOMAIN          502..595
FT                   /note="Fibronectin type-III"
FT                   /evidence="ECO:0000259|PROSITE:PS50853"
FT   REGION          940..1021
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        945..961
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        962..980
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        990..1006
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1098 AA;  124301 MW;  3AB1B8F5C0FF5BE9 CRC64;
     TWSVMLTVLV HVLLMLLAVQ CLRPGAPVHS VALDVPWQDE VCCDSPTAYT YIEEGTSQSD
     LNLPQSPRCK FRSSSGLFNT KPTSEEIGRF STCLDVLCGF DESWSNLTCD LKSSGLSSGM
     MKPIRMAVSL QQISPENDTD YHASEHQVVC DAEDSLMCSI HLNSTRISAV RLTVNVSNVL
     APPVLLRISP RSGNLYWVKP SPPFNLSHVQ TVEGDLIVSW KEPLDFSDDL LAYEIRYSHE
     NTNKNTHKNW QVVSALEKPN VSVDLKPLLK YAIQVRCTTQ TQLWSDWSDP YYITLNKVSY
     IPQMVVARAG DNVTVYCVLN GQSANANTAM WSLNRRVPLD PSLYHPVNQR VSQITFTASE
     TGLSDLLTCT QEWNIPYKCN IFSYHFSKIY VEGGFISITC VTNGDIDTMT CRWENKEWEI
     VKFRSKSAEM SCDEMEERVR GGEDVGEMGH ECMPIKTTEK VCTFHPLKMN CYKLWLELHT
     RLGVIRCKPV YVSPINHVKP HPPTDVTAVS RSGGILRVTW KQPSLPVEGL QCQFRYYLLD
     VLEKWKFEKP VWVPWAEVEV PDMCQIYVVQ VRCMHTSGIG YWSEWSESVH STAQNSRAPE
     RGPDFWRIRQ DDPDRNQSNI TLLFESFSAN WNTYCVDGFI VQHQASNGSV LRRQIDMVSS
     YSFEWNQELH IVTVEAYNSL GSSVNNVNMT LEKQPKRRCL HSFHVLVINS TCVSLSWSLL
     HISSVPLFMV VQWFPRKQQD FEDFGLSKKT WAKLSYSEPP TQLRGDFFSS EEYAFHLYPV
     FADGEGEPVV TIVKTGNPPA YMMLMFISLL CIAVFVTLVL SQNQMKKFVW KDVPNPNKCS
     WAKGVDFKTI DGFEYLFRPP EGLQASPLPP EKISKVTVVN KTLTKAFVQT PTLLAPPSVV
     ASTNSFLPCL NPRTANALVE QSSATTNSSA QSSVTYSKVL HTDTNPDHPP LHLHYKEGSR
     SSYSDEGNFS ANNSDTSETF PGGLWEVDSY HGTESDDPRR SYSYNSEKEL SEVSEQEDDL
     DVGQKKALHY LDIGHPPEDE ENEEEESQTE LLKSAHLIRE DCSAELYPLL NPDDSTDPKT
     LVQVSTCSFS SLYMPQYR
//