ID A0A096MHK5_POEFO Unreviewed; 406 AA.
AC A0A096MHK5;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE RecName: Full=Nucleoporin NUP42 {ECO:0000256|ARBA:ARBA00039886};
DE AltName: Full=Nucleoporin-like protein 2 {ECO:0000256|ARBA:ARBA00042384};
OS Poecilia formosa (Amazon molly) (Limia formosa).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC Poecilia.
OX NCBI_TaxID=48698 {ECO:0000313|Ensembl:ENSPFOP00000030896.1, ECO:0000313|Proteomes:UP000028760};
RN [1] {ECO:0000313|Proteomes:UP000028760}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=female {ECO:0000313|Proteomes:UP000028760};
RA Schartl M., Warren W.;
RL Submitted (OCT-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSPFOP00000030896.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- FUNCTION: Required for the export of mRNAs containing poly(A) tails
CC from the nucleus into the cytoplasm. {ECO:0000256|ARBA:ARBA00037262}.
CC -!- SUBCELLULAR LOCATION: Nucleus membrane {ECO:0000256|ARBA:ARBA00004335};
CC Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004335};
CC Cytoplasmic side {ECO:0000256|ARBA:ARBA00004335}. Nucleus, nuclear pore
CC complex {ECO:0000256|ARBA:ARBA00004567}.
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DR EMBL; AYCK01011352; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; A0A096MHK5; -.
DR Ensembl; ENSPFOT00000025670.1; ENSPFOP00000030896.1; ENSPFOG00000003642.2.
DR GeneTree; ENSGT00390000001338; -.
DR Proteomes; UP000028760; Unassembled WGS sequence.
DR GO; GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005643; C:nuclear pore; IEA:UniProtKB-SubCell.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR Gene3D; 4.10.1000.10; Zinc finger, CCCH-type; 2.
DR InterPro; IPR000571; Znf_CCCH.
DR InterPro; IPR036855; Znf_CCCH_sf.
DR PANTHER; PTHR46527:SF1; NUCLEOPORIN NUP42; 1.
DR PANTHER; PTHR46527; NUCLEOPORIN-LIKE PROTEIN 2; 1.
DR Pfam; PF00642; zf-CCCH; 1.
DR Pfam; PF14608; zf-CCCH_2; 1.
DR SMART; SM00356; ZnF_C3H1; 2.
DR SUPFAM; SSF90229; CCCH zinc finger; 2.
DR PROSITE; PS50103; ZF_C3H1; 2.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723, ECO:0000256|PROSITE-
KW ProRule:PRU00723}; Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000028760};
KW Zinc {ECO:0000256|ARBA:ARBA00022833, ECO:0000256|PROSITE-ProRule:PRU00723};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00723}.
FT DOMAIN 18..46
FT /note="C3H1-type"
FT /evidence="ECO:0000259|PROSITE:PS50103"
FT DOMAIN 91..118
FT /note="C3H1-type"
FT /evidence="ECO:0000259|PROSITE:PS50103"
FT ZN_FING 18..46
FT /note="C3H1-type"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00723"
FT ZN_FING 91..118
FT /note="C3H1-type"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00723"
FT REGION 50..88
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 116..147
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 315..356
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 59..76
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 328..356
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 406 AA; 46470 MW; 32F72962C7A5A848 CRC64;
MENEGEVKTE EEKAESFPQT QQLCRFFSQG RHCHFGKRCR FLHVREDEKD HEKKSFESPS
QPDFTPSNSQ DGGQLEGDNS ALAHNPKFVP GSAHRPCRYF LSGHCTMEDR CRFWHPPQLP
PLDDPSVTAI RSKSTPRHPP EPHPGGLQEV KLCEMTEDTA KQLRDTEIRQ LKKRFPKDQL
IIQEKDGKLT YYRASVEATD PDWPFDLKEV DIMVSFPDNY PLEIFTLEIP LDQNLPSVMA
KHVQEASLEW LQAKHATNQL LGKVELLFRP FLRWLDRSLE RLFTEGARQL KKDIDLEKAG
LQFITYQELQ ISVTETSDPA SGVAGDEDAR NSTEKTEDVD SEEEEHQKPI QSDEGQLLEE
DASHLVENIR ISDPRRGTEV KLLGLRLGEN TATVTAQRIT VCLQCN
//
