ID A0A096MXM5_PAPAN Unreviewed; 702 AA.
AC A0A096MXM5;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 25-MAY-2022, sequence version 3.
DT 27-MAR-2024, entry version 41.
DE SubName: Full=GRAM domain containing 1B {ECO:0000313|Ensembl:ENSPANP00000004647.3};
GN Name=GRAMD1B {ECO:0000313|Ensembl:ENSPANP00000004647.3};
OS Papio anubis (Olive baboon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Papio.
OX NCBI_TaxID=9555 {ECO:0000313|Ensembl:ENSPANP00000004647.3, ECO:0000313|Proteomes:UP000028761};
RN [1] {ECO:0000313|Ensembl:ENSPANP00000004647.3, ECO:0000313|Proteomes:UP000028761}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Liu Y.L., Abraham K.A., Akbar H.A., Ali S.A., Anosike U.A., Aqrawi P.A.,
RA Arias F.A., Attaway T.A., Awwad R.A., Babu C.B., Bandaranaike D.B.,
RA Battles P.B., Bell A.B., Beltran B.B., Berhane-Mersha D.B., Bess C.B.,
RA Bickham C.B., Bolden T.B., Carter K.C., Chau D.C., Chavez A.C.,
RA Clerc-Blankenburg K.C., Coyle M.C., Dao M.D., Davila M.L.D.,
RA Davy-Carroll L.D., Denson S.D., Dinh H.D., Fernandez S.F., Fernando P.F.,
RA Forbes L.F., Francis C.F., Francisco L.F., Fu Q.F., Garcia-Iii R.G.,
RA Garrett T.G., Gross S.G., Gubbala S.G., Hirani K.H., Hogues M.H.,
RA Hollins B.H., Jackson L.J., Javaid M.J., Jhangiani S.J., Johnson A.J.,
RA Johnson B.J., Jones J.J., Joshi V.J., Kalu J.K., Khan N.K., Korchina V.K.,
RA Kovar C.K., Lago L.L., Lara F.L., Le T.-K.L., Lee S.L., Legall-Iii F.L.,
RA Lemon S.L., Liu J.L., Liu Y.-S.L., Liyanage D.L., Lopez J.L.,
RA Lorensuhewa L.L., Mata R.M., Mathew T.M., Mercado C.M., Mercado I.M.,
RA Morales K.M., Morgan M.M., Munidasa M.M., Ngo D.N., Nguyen L.N.,
RA Nguyen T.N., Nguyen N.N., Obregon M.O., Okwuonu G.O., Ongeri F.O.,
RA Onwere C.O., Osifeso I.O., Parra A.P., Patil S.P., Perez A.P., Perez Y.P.,
RA Pham C.P., Pu L.-L.P., Puazo M.P., Quiroz J.Q., Rouhana J.R., Ruiz M.R.,
RA Ruiz S.-J.R., Saada N.S., Santibanez J.S., Scheel M.S., Schneider B.S.,
RA Simmons D.S., Sisson I.S., Tang L.-Y.T., Thornton R.T., Tisius J.T.,
RA Toledanes G.T., Trejos Z.T., Usmani K.U., Varghese R.V., Vattathil S.V.,
RA Vee V.V., Walker D.W., Weissenberger G.W., White C.W., Williams A.W.,
RA Woodworth J.W., Wright R.W., Zhu Y.Z., Han Y.H., Newsham I.N.,
RA Nazareth L.N., Worley K.W., Muzny D.M., Rogers J.R., Gibbs R.G.;
RT "Whole Genome Assembly of Papio anubis.";
RL Submitted (MAR-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSPANP00000004647.3}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004162};
CC Single-pass membrane protein {ECO:0000256|ARBA:ARBA00004162}.
CC Endoplasmic reticulum membrane {ECO:0000256|ARBA:ARBA00004389}; Single-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004389}. Membrane
CC {ECO:0000256|ARBA:ARBA00004167}; Single-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004167}.
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DR AlphaFoldDB; A0A096MXM5; -.
DR Ensembl; ENSPANT00000010578.4; ENSPANP00000004647.3; ENSPANG00000018864.4.
DR GeneTree; ENSGT00940000156649; -.
DR HOGENOM; CLU_015189_1_0_1; -.
DR Proteomes; UP000028761; Chromosome 12.
DR Bgee; ENSPANG00000018864; Expressed in adrenal medulla and 66 other cell types or tissues.
DR ExpressionAtlas; A0A096MXM5; baseline.
DR GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0044232; C:organelle membrane contact site; IEA:UniProt.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR CDD; cd13220; PH-GRAM_GRAMDC; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR004182; GRAM.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR031968; VASt.
DR PANTHER; PTHR23319:SF3; PROTEIN ASTER-B; 1.
DR PANTHER; PTHR23319; UNCHARACTERIZED; 1.
DR Pfam; PF02893; GRAM; 1.
DR Pfam; PF16016; VASt; 1.
DR SMART; SM00568; GRAM; 1.
DR PROSITE; PS51778; VAST; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000028761};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 587..611
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 336..507
FT /note="VASt"
FT /evidence="ECO:0000259|PROSITE:PS51778"
FT REGION 218..265
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 508..530
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 222..260
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 702 AA; 81802 MW; 605FB3EA226B3E08 CRC64;
MESLTESGVL WSLLLEQESQ LLQWYLKQLG HAPAAAEHHC WHGSEEIPAV LSPTYKQRNE
DFRKLFKQLP DTERLIVDYS CALQRDILLQ GRLYLSENWI CFYSNIFRWE TLLTVRLKDI
CSMTKEKTAR LIPNAIQVCT DSEKHFFTSF GARDRTYMMM FRLWQNALLE KPLCPKELWH
FVHQCYGNEL GLTSDDEDYV PPDDDFNTMG YCEEIPVEEN EVNDSSSKSS IETKPDASPQ
LPKKSITNST LTSTGSSEAP VSFDGLPLEE EALEGDGSLE KELAIDNIMG EKIEMIAPVN
SPSLDFNDNE DIPTELSDSS DTHDEGEVQA FYEDLSGRQY VNEVFNFSVD KLYDLLFTNS
PFQRDFMEQR RFSDIIFHPW KKEENGNQSR VILYTITLTN PLAPKTATVR ETQTMYKASQ
ESECYVIDAE VLTHDVPYHD YFYTINRYTL TRVARNKSRL RVSTELRYRK QPWGLVKTFI
EKNFWSGLED YFRHLESELA KTESTYLAEM HRQSPKEKAS KTTTVRRRKR PHAHLRVPHL
EEVMSPVTTP TDEDVGHRIK HVAGSTQTRH IPEDTPNGFH LQSVSKLLLV ISCVICFSLV
LLVILNMMLF YKLWMLEYTT QTLTAWQGLR LQERLPQSQT EWAQLLESQQ KYHDTELQKW
REIIKSSVML LDQMKDSLIN LQNGIRSRDY TSESEEKRNR YH
//
